Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rao V. Mantri"'
Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preform
Autor:
Yusuf O. Oni, Jason Franck, Christina Evans, Daniel Paniagua, Ankur Kulshrestha, Rao V. Mantri
Publikováno v:
PDA journal of pharmaceutical science and technology.
As the complexities of pharmaceuticals needed to prevail over serious diseases continue to grow, the need for technologies to enable their efficient storage and delivery are as essential as ever. Lately, drugs such as vaccines, proteins, and stem cel
Autor:
Jason Franck, Roger Asselta, Yusuf Oni, Matthew Schrader, Carolina Flores-Crespo, Rao V. Mantri, Ankur Kulshrestha, Xu Song
Publikováno v:
PDA journal of pharmaceutical science and technology. 73(6)
Container closure integrity (CCI) is one of the requirements for a sterile packaging system. For vial-based systems, the capping process is a critical step in creating and ensuring an adequate seal with acceptable CCI. Container closure integrity tes
Publikováno v:
Journal of Pharmaceutical Innovation. 11:200-213
Modeling approaches play a valuable role at various stages of development and life-cycle management of biopharmaceutical products. In Quality-by-Design (QbD) paradigm, quality needs to be designed into the product rather than merely confirming it thr
Autor:
Rao V. Mantri, Alexej Jerschow, Dolapo Olusanmi, Daniel McNamara, Andrew J. Ilott, David Good, Murphy Denette K, Anuji Abraham
Publikováno v:
Journal of Pharmaceutical Sciences. 105:1907-1913
Understanding the behavior of tablet disintegrants is valuable in the development of pharmaceutical solid dosage formulations. In this study, high-resolution magnetic resonance imaging has been used to understand the hydration behavior of a series of
Publikováno v:
AAPS PharmSciTech. 18:42-48
This study aimed in understanding the degradation behaviors of an IgG 1 subtype therapeutic monoclonal antibody A (mAb-A) associated with pH and buffer species. The information obtained in this study can augment conventional, stability-based screenin
Publikováno v:
AAPS PharmSciTech. 16:1317-1326
Lyophilization is an approach commonly undertaken to formulate drugs that are unstable to be commercialized as ready to use (RTU) solutions. One of the important aspects of commercializing a lyophilized product is to transfer the process parameters t
Excipient selection is based on their functionality, compatibility, and variability of critical material attributes within an acceptable range for a given drug product. Drug-excipient compatibility studies are usually used as a screening tool to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d767cddf239661a379c2822f65d905
https://doi.org/10.1016/b978-0-12-802447-8.00006-6
https://doi.org/10.1016/b978-0-12-802447-8.00006-6
Publikováno v:
Journal of pharmaceutical sciences. 105(3)
To support dose reduction, low dose of a monoclonal antibody (mAb) was required to be administered via IV infusion at a concentration of 0.1 mg/mL. To achieve the target protein concentration, the infusion solution was prepared by diluting the drug p
Autor:
Levons Jaquan Kalani, Rao V. Mantri, Ajit S. Narang, Yongmei Wu, Krishnaswamy Srinivas Raghavan
Publikováno v:
Excipient Applications in Formulation Design and Drug Delivery ISBN: 9783319202051
Reactive impurities in pharmaceutical excipients can affect drug product instability, leading to decreased product performance, loss in potency, and/or formation of potentially toxic degradants. The levels of reactive impurities in excipients may var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bbd8887e5024bf8c958a27f3ad4f8e2
https://doi.org/10.1007/978-3-319-20206-8_3
https://doi.org/10.1007/978-3-319-20206-8_3