Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rao Muzaffar A. Khan"'
Publikováno v:
Acta Chromatographica. 27:435-448
A rapid, accurate, and sensitive reverse phase high-performance liquid chromatographic method was developed and validated for the simultaneous determination and quantification of glibenclamide and thymoquinone in rat plasma in the presence of interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f4ee6c4be478326497c69b712523f2
https://doi.org/10.1556/achrom.27.2015.3.3
https://doi.org/10.1556/achrom.27.2015.3.3
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 36:2242-2250
The chemical compound thymoquinone (THQ) isolated from Nigella sativa seed oil has multiple therapeutic potentials. A simple and rapid reversed-phase high-performance liquid chromatography assay was developed to determine the concentration of THQ in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::310b21989ea14bdb1ea371aedb193603
https://doi.org/10.1080/10826076.2012.717062
https://doi.org/10.1080/10826076.2012.717062
Autor:
Saleh A. Al-Suwayeh, Abdullah M. Al-Mohizea, Rao Muzaffar A. Khan, Ajaz Ahmad, Khalid M. Alkharfy, Fahad I. Al-Jenoobi
Publikováno v:
Phytotherapy Research. 27:1800-1804
The present work was designed to evaluate the effect of some commonly used herbs viz. garden cress (Lepidium sativum), black seed (Nigella sativa) and fenugreek (Trigonella foenum-graceum) on the disposition of phenytoin after oral administration in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c2d5e5f293ea16bb246243d203fb065
https://doi.org/10.1002/ptr.4947
https://doi.org/10.1002/ptr.4947
Autor:
Rafiq R. Abou-Shaaban, Badraddin M.H. Al-Hadiya, Hisham S. Abou-Auda, Khalid M. Alkharfy, Rao Muzaffar A. Khan
Publikováno v:
Biopharmaceutics & Drug Disposition. 28:105-111
Abouthiouzine is a novel antithyroid agent with a profile of fewer reported adverse effects than other currently used drugs. The purpose of this current work was to explore, for the first time, the disposition of abouthiouzine following intravenous a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a63dd98abdb6452a3d4c59f872455a9
https://doi.org/10.1002/bdd.536
https://doi.org/10.1002/bdd.536
Effects of Thymoquinone on the Pharmacokinetics and Pharmacodynamics of Glibenclamide in a Rat Model
Autor:
Ajaz, Ahmad, Rao Muzaffar A, Khan, Khalid M, Alkharfy, Mohammad, Raish, Fahad I, Al-Jenoobi, Abdullah M, Al-Mohizea
Publikováno v:
Natural product communications. 10(8)
Glibenclamide and thymoquinone plasma concentrations were analysed using a sensitive RP-HPLC method, and non-compartmental model pharmacokinetic parameters were calculated. The maximum reduction in blood glucose level was observed 3 hours following g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e876138c7cb625aae8830216bcfac6fb
https://pubmed.ncbi.nlm.nih.gov/26434126
https://pubmed.ncbi.nlm.nih.gov/26434126
Publikováno v:
Veterinary Anaesthesia and Analgesia. 33:241-245
Diclofenac is an important nonsteroidal anti-inflammatory drug that is commonly used in both humans and animals. The aim of this work was to examine the pharmacokinetics of diclofenac in sheep after intravenous and intramuscular dosing. Diclofenac (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676d9112d5097541ede34c47ecf6077b
https://doi.org/10.1111/j.1467-2995.2005.00256.x
https://doi.org/10.1111/j.1467-2995.2005.00256.x
Autor:
Hisham S. Abou-Auda, Rao Muzaffar A. Khan, Badraddin M.H. Al-Hadiya, Rafiq R. Abou-Shaaban, Khalid M. Alkharfy
Publikováno v:
Journal of Chromatography B. 817:183-186
Abouthiouzine is a newly synthesized antithyroid agent with a proposed less adverse effects profile than other currently used drugs. A simple and rapid reversed phase high performance liquid chromatography assay was developed to determine the concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728ae91dbf60b229743d4abff2ff40ff
https://doi.org/10.1016/j.jchromb.2004.12.001
https://doi.org/10.1016/j.jchromb.2004.12.001
Autor:
Rao Muzaffar A. Khan, Mohammad Raish, Muzaffar Iqbal, Khalid A. Al-Rashood, Essam Ezzeldin, T Anwer, K I Al-Khamees
Publikováno v:
Drug research. 64(8)
Zafirlukast is a selective leukotriene receptor antagonist used for the prophylaxis and chronic treatment of asthma. The aim of the present study was to develop a simple sensitive ultra-performance liquid chromatography tandem mass spectroscopy metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5c640de14d256158778b2e959b46ee
https://pubmed.ncbi.nlm.nih.gov/24258705
https://pubmed.ncbi.nlm.nih.gov/24258705
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 40(3)
Thymoquinone (THQ), the active constituent of Nigella sativa seeds, has demonstrated some potential pharmacological activities. The present study was designed to investigate the pharmacokinetic behavior of THQ following intravenous (IV) and oral (PO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10f171cf7e5cbff483e802f4b135c81
https://pubmed.ncbi.nlm.nih.gov/24924310
https://pubmed.ncbi.nlm.nih.gov/24924310
Autor:
Iqbal Muzaffar, Saleh A. Al-Suwayeh, Abdullah M. Al-Mohizea, Fahad I. Al-Jenoobi, Hesham M. Korashy, Rao Muzaffar A. Khan, Mohd Aftab Alam, Khalid M. Alkharfy
Publikováno v:
Drug metabolism letters. 7(1)
Efficacy and safety profile of a drug may be affected when concomitantly used with herbal medicines. The present study was conducted to investigate the effects of some commonly used herbal products viz. Nigella sativa (Black seed) and Lepidium sativu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02c9b2d697df2ca319521598f591ab1
https://pubmed.ncbi.nlm.nih.gov/23952676
https://pubmed.ncbi.nlm.nih.gov/23952676