Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rao H. Prabhala"'
Autor:
Srikanth Talluri, Mehmet K. Samur, Leutz Buon, Subodh Kumar, Lakshmi B. Potluri, Jialan Shi, Rao H. Prabhala, Masood A. Shammas, Nikhil C. Munshi
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 10, Pp 1-11 (2021)
Abstract Multiple myeloma (MM) is a heterogeneous disease characterized by significant genomic instability. Recently, a causal role for the AID/APOBEC deaminases in inducing somatic mutations in myeloma has been reported. We have identified APOBEC/AI
Externí odkaz:
https://doaj.org/article/d13895ee298b46c692921d6655cf5d13
Autor:
Kenneth C. Anderson, Nikhil C. Munshi, Ruben D. Carrasco, Tomasz Sewastianik, Dharminder Chauhan, Paul G. Richardson, Yu-Tzu Tai, Kenneth Wen, Srikanth Talluri, Rao H. Prabhala, Stefano Malvestiti, Mariateresa Fulciniti, Giada Bianchi, Teru Hideshima, Cirino Botta, Mehmet K. Samur, Eugenio Morelli, Annamaria Gulla
The proteasome inhibitor bortezomib induces apoptosis in multiple myeloma cells and has transformed patient outcome. Using in vitro as well as in vivo immunodeficient and immunocompetent murine multiple myeloma models, we here show that bortezomib al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e138169ee058e491ce199859459794f
https://doi.org/10.1158/2643-3230.c.6550306.v1
https://doi.org/10.1158/2643-3230.c.6550306.v1
Autor:
Kenneth C. Anderson, Nikhil C. Munshi, Ruben D. Carrasco, Tomasz Sewastianik, Dharminder Chauhan, Paul G. Richardson, Yu-Tzu Tai, Kenneth Wen, Srikanth Talluri, Rao H. Prabhala, Stefano Malvestiti, Mariateresa Fulciniti, Giada Bianchi, Teru Hideshima, Cirino Botta, Mehmet K. Samur, Eugenio Morelli, Annamaria Gulla
Supp. table S1 shows immune genes regulated after treatment with bortezomib in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ff9f2514cea565acc4e55d70918a38
https://doi.org/10.1158/2643-3230.22543531
https://doi.org/10.1158/2643-3230.22543531
Autor:
Kenneth C. Anderson, Nikhil C. Munshi, Ruben D. Carrasco, Tomasz Sewastianik, Dharminder Chauhan, Paul G. Richardson, Yu-Tzu Tai, Kenneth Wen, Srikanth Talluri, Rao H. Prabhala, Stefano Malvestiti, Mariateresa Fulciniti, Giada Bianchi, Teru Hideshima, Cirino Botta, Mehmet K. Samur, Eugenio Morelli, Annamaria Gulla
Supp. Fig. 1 shows that bortezomib induces ICD in vitro. Suppl. Fig.2 shows that bortezomib treatment of co-culture of dendritic and T cells does not induce T cell maturation. Suppl. Fig. 3 shows that bortezomib-induced MM cell death promotes prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533b49d502717094d623e99c61698ded
https://doi.org/10.1158/2643-3230.22543534.v1
https://doi.org/10.1158/2643-3230.22543534.v1
Autor:
Noopur S Raje, Elias Anaissie, Shaji K Kumar, Sagar Lonial, Thomas Martin, Morie A Gertz, Amrita Krishnan, Parameswaran Hari, Heinz Ludwig, Elizabeth O'Donnell, Andrew Yee, Jonathan L Kaufman, Adam D Cohen, Laurent Garderet, Ashutosh F Wechalekar, Evangelos Terpos, Navin Khatry, Ruben Niesvizky, Qing Yi, Douglas E Joshua, Tapan Saikia, Nelson Leung, Monika Engelhardt, Mohamad Mothy, Andrew Branagan, Ajai Chari, Anthony J Reiman, Brea Lipe, Joshua Richter, S Vincent Rajkumar, Jesús San Miguel, Kenneth C Anderson, Edward A Stadtmauer, Rao H Prabhala, Phillip L McCarthy, Nikhil C Munshi
Publikováno v:
The Lancet Haematology. 9:e143-e161
Infection remains the leading cause of morbidity and mortality in patients with multiple myeloma because of the cumulative effect of disease, treatment, and host-related factors. Given that infectious risk is cumulative through the course of the dise
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97566 (2014)
Interactions between the inflammatory chemokine CCL20 and its receptor CCR6 have been associated with colorectal cancer growth and metastasis, however, a causal role for CCL20 signaling through CCR6 in promoting intestinal carcinogenesis has not been
Externí odkaz:
https://doaj.org/article/ef768ab287c140febdb1d4f1c8523c72
Publikováno v:
The Journal of Immunology. 204:144.6-144.6
We previously found that NLRP3 inflammasome activity is a critical mechanism regulating sleep and slow-waves. Microglia and astrocytes play a major role in sleep regulation and altering slow-waves. We investigated the contribution of NLRP3 inflammaso
Autor:
Rao H, Prabhala, Nikhil C, Munshi
Publikováno v:
Hematology/Oncology Clinics of North America. 21:1217-1230
Incidents of cancer, particularly in elderly patients living in developing countries, are predicted to raise significantly as the general population rises to an estimated 8.9 billion by the year 2050. Immune cells with specific functions and abilitie
Autor:
Angela Aidala, Ana Maria Rampeloti Almeida, Giovanni Nardin Alves, Aranka Anema, Jose Luis Agud Aparicio, Katelyn Baron, Sarah Beadle, Annie Bello, Elizabeth Blanchard, Tom Bonderenko, Marc Bulterys, Tomás Campbell, Rana Chakraborty, Ubilina Maria da Conceição Maia, Erika Aparecida da Silveira, Marianne de Oliveira Falco, Ana Celia Oliveira dos Santos, Alastair Duncan, Walter L. Ellis, Logan Paolo L. Felix, Vani Gandhi, Concepción García-Lacalle, Nils Grede, Allen T. Griffin, Nazisa Hejazi, Deborah Hinde, Christine Hughes, Muhammed Zafar Iqbal Hydrie, Miguel Cervero Jiménez, Magid Kagimu, Mohammad Ehsanul Karim, Thomas Kerr, Maria Irany Knackfuss, Athena P. Kourtis, Lauren E. Lawson, Victoria Alcazar Lázaro, Sonill Sooknunan Maharaj, Lawrence C. McCandless, Chelsea N. McMahon, Divya Mehra, M-J Milloy, Jacqueline Pontes Monteiro, Robert Kelechi Obi, Tim O’Keeffe, Gaurav Paul, Karen Pearl, Neelima D. Prabhala, Rao H. Prabhala, George Psevdos, Roslee Rajikan, Poul Rohleder, Roberta Garcia Salomão, Katherine Samaras, Fabiana Schuelter-Trevisol, Richard Ferreira Sene, Jamila Sheikh, Vijay Singh, Themis Cristina Mesquita Soares, Katarzyna Szarlej-Wcislo, Srikanth Talluri, Daisson José Trevisol, Helena Siqueira Vassimon, Nicholas Vogenthaler, Sunita Vohra, Alissa Wassung, David Waters, Ronald Ross Watson, Gabriel Wcislo, Sheri Weiser, Kevin Winge, Evan Wood, Bridget A. Wynn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961d3395f9b28002577f081ca1aecf19
https://doi.org/10.1016/b978-0-12-800769-3.00038-x
https://doi.org/10.1016/b978-0-12-800769-3.00038-x