Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma

Autor: Sun, Yunfan ^{1, 14, ∗}, Wu, Pin ^{2, 3, 4, 11, 14}, Zhang, Zefan ^{1, 14}, Wang, Zejian ^{2, 3, 4, 14}, Zhou, Kaiqian ^{1, 14}, Song, Minfang ^{5, 14}, Ji, Yuan ^{6, 14}, Zang, Fenglin ^{7, 14}, Lou, Limu ^{2, 3}, Rao, Keqiang ¹, Wang, Pengxiang ¹, Gu, Yutong ⁸, Gu, Jie ⁹, Lu, Binbin ¹⁰, Chen, Limeng ¹⁰, Pan, Xiuqi ^{2, 3}, Zhao, Xiaojing ^{2, 3}, Peng, Lihua ^{11, 12}, Liu, Dongbing ^{11, 12}, Chen, Xiaofang ^{11, 12}, Wu, Kui ^{11, 12}, Lin, Penghui ^{11, 12}, Wu, Liang ¹¹, Su, Yulin ^{2, 3}, Du, Min ¹³, Hou, Yingyong ⁶, Yang, Xinrong ¹, Qiu, Shuangjian ¹, Shi, Yinghong ¹, Sun, Huichuan ¹, Zhou, Jian ¹, Huang, Xingxu ⁵, Peng, David H. ^{10, ∗∗}, Zhang, Liye ^{2, 3, ∗∗∗}, Fan, Jia ^{1, 15, ∗∗∗∗}

Publikováno v: In Cancer Cell 8 January 2024 42(1):135-156

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Deficiency of TET2-mediated KMT2D self-transcription confers a targetable vulnerability in hepatocellular carcinoma.

Autor: Jin Y; Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China., Rao K; Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China., Zheng J; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China., Zhang X; Department of Pathology, College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Luo Y; Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China., He J; Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China.

Publikováno v: PNAS nexus [PNAS Nexus] 2024 Nov 11; Vol. 3 (11), pp. pgae504. Date of Electronic Publication: 2024 Nov 11 (Print Publication: 2024).