Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ranyia Matta"'
Autor:
Yusen Liu, Ranyia Matta, Jing Yan, Jianjing Xue, Jessica L. Grieves, W. Joshua Frazier, Andrew C.B. Cato, Leif D. Nelin, John Barnard, Lyn M. Wancket
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G1322-G1335
Il-10-deficient mice develop colitis associated with exaggerated Th1/Th17 responses and are a valuable model of inflammatory bowel disease. Mkp-1 is a major negative regulator of MAPKs, and its expression is enhanced by IL-10. To understand the role
Autor:
Xiaomei Meng, Yusen Liu, Chang-Gong Liu, Qun Zhao, Leif D. Nelin, Ranyia Matta, Xiuping Liu, Xianxi Wang
Publikováno v:
Journal of Biological Chemistry. 284:27123-27134
Inducible nitric-oxide (NO) synthase (iNOS) plays a critical role in the eradication of intracellular pathogens. However, the excessive production of NO by iNOS has also been implicated in the pathogenesis of septic shock syndrome. Previously, we hav
Autor:
Myung Ja Kwon, Yongxue Yao, Soon Choel Hong, Yusen Liu, Ranyia Matta, Qi Xu, Cheong Hee Chang
Publikováno v:
The Journal of Immunology. 177:70-76
The CIITA is a master regulator for MHC class II expression, but the signaling events that control CIITA expression remain poorly understood. In this study, we report that both constitutive and IFN-γ-inducible expression of CIITA in mouse bone marro
Publikováno v:
Journal of Molecular Medicine. 84:405-415
Triptolide is a compound extracted from the Chinese herb Tripterygium wilfordii Hook. f. Triptolide has potent anticancer activity. However, the mechanisms by which triptolide exerts its anticancer activities remain unclear. To explore the molecular
Publikováno v:
American journal of translational research. 1(3)
Tripterygium wilfordii Hook F. has been used for centuries in traditional Chinese medicine to treat rheumatoid arthritis, an autoimmune disease associated with increased production of the pro-inflammatory cytokine, tumor necrosis factor (TNF)-alpha.
Autor:
Reshma S. Baliga, Qun Zhao, Yusen Liu, Ranyia Matta, Xianxi Wang, Mary E. Manson, Yongxue Yao, Xiaomei Meng, Leif D. Nelin, Cheong Hee Chang, John Anthony Bauer, Charles V. Smith
Publikováno v:
The Journal of Experimental Medicine
Septic shock is a leading cause of morbidity and mortality. However, genetic factors predisposing to septic shock are not fully understood. Excessive production of proinflammatory cytokines, particularly tumor necrosis factor (TNF)-α, and the result
Autor:
Yusen Liu, Ranyia Matta, John Barnard, Lyn Wancket, Jing Yan, Jessica Grieves, W. Joshua Frazier, Leif Nelin, Andrew Cato
Publikováno v:
The Journal of Immunology. 188:120.21-120.21
Il-10-/- mice develop colitis associated with exaggerated Th1/Th17 responses. Mkp-1 is a negative regulator of MAPKs, and its expression is enhanced by IL-10. To understand the role of Mkp-1 in the regulation of mucosal immune responses, we studied t
Publikováno v:
The Journal of Immunology. 184:47.7-47.7
IBD is a chronic intestinal inflammatory disease that often has extra-intestinal manifestations. We examined the role of the MAPK phosphatase Mkp-1 in a mouse model of IBD. Mkp-1+/+/Il-10+/+, Mkp-1-/-/Il-10+/+, Mkp-1+/+/Il-10-/-, and Mkp-1-/-/Il-10-/