Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ranveer Singh Jayani"'
Autor:
Kaivalya Walavalkar, Bharath Saravanan, Anurag Kumar Singh, Ranveer Singh Jayani, Ashwin Nair, Umer Farooq, Zubairul Islam, Deepanshu Soota, Rajat Mann, Padubidri V. Shivaprasad, Matthew L. Freedman, Radhakrishnan Sabarinathan, Christopher A. Haiman, Dimple Notani
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Genetic variants on chromosome 8q24 are associated with prostate cancer risk in men of African ancestry. Here the authors show that one of these variants, rs72725854 alters the enhancer activity in its region, which upon androgen stimulation, activat
Externí odkaz:
https://doaj.org/article/93438dabdd644b0eb1657d432722a153
Autor:
Umer Farooq, Bharath Saravanan, Zubairul Islam, Kaivalya Walavalkar, Anurag Kumar Singh, Ranveer Singh Jayani, Sweety Meel, Sudha Swaminathan, Dimple Notani
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108898- (2021)
Summary: The INK4a/ARF locus encodes important cell-cycle regulators p14ARF, p15INK4b, and p16INK4a. The neighboring gene desert to this locus is the most reproducible GWAS hotspot that harbors one of the densest enhancer clusters in the genome. Howe
Externí odkaz:
https://doaj.org/article/2bada0eb90ae4d498daae0534e9a6823
Autor:
Qi Ma, Feng Yang, Carlos Mackintosh, Ranveer Singh Jayani, Soohwan Oh, Chunyu Jin, Sreejith Janardhanan Nair, Daria Merkurjev, Wubin Ma, Stephanie Allen, Dong Wang, Angels Almenar-Queralt, Ivan Garcia-Bassets
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Cisplatin is an antineoplastic drug administered at suboptimal and intermittent doses to avoid life-threatening effects. Although this regimen shortly improves symptoms in the short term, it also leads to more malignant disease in the long t
Externí odkaz:
https://doaj.org/article/50ac903137cb4210b15ac40955ec50f1
Autor:
Radhakrishnan Sabarinathan, Umer Farooq, Anurag Kumar Singh, Kaivalya Walavalkar, Matthew L. Freedman, Ashwin Nair, Ranveer Singh Jayani, Rajat Mann, Bharath Saravanan, Padubidri V. Shivaprasad, Zubairul Islam, Dimple Notani, Deepanshu Soota, Christopher A. Haiman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Genetic variation at the 8q24 locus is linked with the greater susceptibility to prostate cancer in men of African ancestry. One such African ancestry specific rare variant, rs72725854 (A>G/T) (~6% allele frequency) has been associated with a ~2-fold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75882c73359408c698530a8914473e7
http://link.springer.com/article/10.1038/s41467-020-17325-y
http://link.springer.com/article/10.1038/s41467-020-17325-y
Autor:
Qi Ma, Kenneth A. Ohgi, Tom Suter, Soohwan Oh, Priya R. Banerjee, Lu Yang, Jie Zhang, Meyer J. Friedman, Amir Gamliel, Yiren Hu, Aneel K. Aggarwal, Feng Yang, Dario Meluzzi, Susan Wang, Ranveer Singh Jayani, Yuliang Tan, Ibraheem Alshareedah, Sreejith J Nair, Michael G. Rosenfeld
Publikováno v:
Nature structural & molecular biology, vol 26, iss 3
A crucial feature of differentiated cells is the rapid activation of enhancer-driven transcriptional programs in response to signals. The potential contributions of physicochemical properties of enhancer assembly in signaling events remain poorly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60dbddbe4124804483d8e658b8c8b6ba
https://doi.org/10.1038/s41594-019-0190-5
https://doi.org/10.1038/s41594-019-0190-5
Autor:
Ranveer Singh Jayani, Sudha Swaminathan, Dimple Notani, Umer Farooq, Zubairul Islam, Kaivalya Walavalkar, Sweety Meel, Anurag Kumar Singh, Bharath Saravanan
Publikováno v:
Cell reports
Cell Reports, Vol 34, Iss 12, Pp 108898-(2021)
Cell Reports, Vol 34, Iss 12, Pp 108898-(2021)
Summary The INK4a/ARF locus encodes important cell-cycle regulators p14ARF, p15INK4b, and p16INK4a. The neighboring gene desert to this locus is the most reproducible GWAS hotspot that harbors one of the densest enhancer clusters in the genome. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928b82555962141fc04318066800b558
https://pubmed.ncbi.nlm.nih.gov/33761351
https://pubmed.ncbi.nlm.nih.gov/33761351
Autor:
Soohwan Oh, Feng Yang, Ranveer Singh Jayani, Daria Merkurjev, Wubin Ma, Chunyu Jin, Qi Ma, Ivan Garcia-Bassets, Stephanie Allen, Dong Wang, Carlos Mackintosh, Sreejith J Nair, Angels Almenar-Queralt
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp-(2020)
Summary: Cisplatin is an antineoplastic drug administered at suboptimal and intermittent doses to avoid life-threatening effects. Although this regimen shortly improves symptoms in the short term, it also leads to more malignant disease in the long t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530b2688bed2b4e04e395c2f421b296c
http://www.sciencedirect.com/science/article/pii/S2211124720304320
http://www.sciencedirect.com/science/article/pii/S2211124720304320
Autor:
Angels Almenar-Queralt, Daria Merkurjev, Stephanie Allen-Soltero, Carlos Mackintosh, Sreejith J Nair, Ranveer Singh Jayani, Wubin Ma, Qi Ma, Feng Yang, Ivan Garcia-Bassets, Dong Wang
Publikováno v:
SSRN Electronic Journal.
Anticancer drugs with narrow therapeutic window, such as cisplatin, are administrated at suboptimal and intermittent doses to limit their adverse effects in patients. This regimen may allow survival of cancer cells that problematically also gain mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d10fb2d234b2662f1256539791a2524
https://doi.org/10.2139/ssrn.3413899
https://doi.org/10.2139/ssrn.3413899
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1543
Noncoding RNAs, being at the center stage of the organismal development and homeostasis, warrant a detailed analysis to utilize their full therapeutic potential. They form complexes with various proteins that enable the noncoding RNAs to acquire spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1a436a4dbd2eec2c2c255f7eba736da
https://pubmed.ncbi.nlm.nih.gov/28349427
https://pubmed.ncbi.nlm.nih.gov/28349427
Publikováno v:
Methods in Molecular Biology ISBN: 9781493967148
Noncoding RNAs, being at the center stage of the organismal development and homeostasis, warrant a detailed analysis to utilize their full therapeutic potential. They form complexes with various proteins that enable the noncoding RNAs to acquire spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fa6d01af180e54bcefef92d9516fdbe
https://doi.org/10.1007/978-1-4939-6716-2_9
https://doi.org/10.1007/978-1-4939-6716-2_9
