Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ranu S. Sinniah"'
Autor:
Colleen M. Connelly, Tomoyuki Numata, Robert E. Boer, Michelle H. Moon, Ranu S. Sinniah, Joseph J. Barchi, Adrian R. Ferré-D’Amaré, John S. Schneekloth
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
RNA sensors—Riboswitches—respond to the binding of small molecules ligands through structure modification. Here the authors identify synthetic small molecules that bind and regulate the activity of PreQ1 Riboswitches despite having no obvious che
Externí odkaz:
https://doaj.org/article/8034f2bb7b9a4f67ba723ce0a274264d
Publikováno v:
Expert Opinion on Investigational Drugs. 30:1047-1056
The development of novel biomarkers for cancer has exploded over the last decade with advances in novel technologies. Cholangiocarcinoma (CCA), a cancer of the bile ducts, has a dearth of strong disease and pathophysiology biomarkers, making early de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3cee33c0cc549eaaf10815c591e72cb
https://doi.org/10.1080/13543784.2021.1985461
https://doi.org/10.1080/13543784.2021.1985461
Autor:
Hsien-Chao Chou, Anna M. Chiarella, Jiji Chen, Javed Khan, Sukriti Bagchi, Xinyu Wen, Ranu S Sinniah, Ashley Walton, Nathaniel A. Hathaway, Silvia Pomella, Young Min Song, Jack F. Shern, Xiaoli S. Wu, Christopher R. Vakoc, Benjamin Z. Stanton, Berkley E. Gryder, Keji Zhao, Rossella Rota, Carly M. Sayers
Publikováno v:
Nature genetics
Core regulatory transcription factors (CR TFs) orchestrate the placement of super-enhancers (SEs) to activate transcription of cell-identity specifying gene networks, and are critical in promoting cancer. Here, we define the core regulatory circuitry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003017e0b7efbc5cd501cf8f53fed6b3
http://europepmc.org/articles/PMC6886578
http://europepmc.org/articles/PMC6886578
Autor:
Ranu S. Sinniah, Adrian R. Ferré-D'Amaré, Joseph J. Barchi, Michelle H. Moon, Colleen M. Connelly, Robert E. Boer, John S. Schneekloth, Tomoyuki Numata
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Riboswitches are naturally occurring RNA aptamers that regulate gene expression by binding to specific small molecules. Riboswitches control the expression of essential bacterial genes and are important models for RNA-small molecule recognition. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ac141f7122e2c41b118709718d9083
https://doaj.org/article/8034f2bb7b9a4f67ba723ce0a274264d
https://doaj.org/article/8034f2bb7b9a4f67ba723ce0a274264d
Autor:
Ranu S Sinniah, Josh Kowalczyk, Berkley E. Gryder, Robert Hawley, Yong Yean Kim, Young Song, Silvia Pomella, Javed Khan
Publikováno v:
Cancer Research. 80:4175-4175
Background: PAX3/7-FOXO1 fusion gene is the major oncogenic driver in fusion positive rhabdomyosarcoma (FP-RMS), a highly aggressive soft tissue sarcoma of childhood. The chimeric gene results from either t(2;13) or t(1;13) translocation and has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8631e24ca5a18b1f9e95079bc5b976ee
https://doi.org/10.1158/1538-7445.am2020-4175
https://doi.org/10.1158/1538-7445.am2020-4175
Autor:
Colleen M, Connelly, Tomoyuki, Numata, Robert E, Boer, Michelle H, Moon, Ranu S, Sinniah, Joseph J, Barchi, Adrian R, Ferré-D'Amaré, John S, Schneekloth
Publikováno v:
Nature Communications
Riboswitches are naturally occurring RNA aptamers that regulate gene expression by binding to specific small molecules. Riboswitches control the expression of essential bacterial genes and are important models for RNA-small molecule recognition. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95419e1ad44bf64641f50c19b0720795
https://pubmed.ncbi.nlm.nih.gov/30940810
https://pubmed.ncbi.nlm.nih.gov/30940810