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Ex Vivo Venetoclax Sensitivity Testing Predicts Response and Overall Survival in De Novo and s/R/R AML Patients Treated with Azacitidine and Venetoclax

Autor: Kytölä, Sari ^*, Vänttinen, Ida ^*, Ruokoranta, Tanja ^*, Holopainen, Annasofia ^*, Partanen, Anu ^*, Kuusisto, Milla E.L. ^*, Koskela, Sirpa ^*, Räty, Riikka ^*, Itälä-Remes, Maija ^*, Ranta, Amanda ^*, Suvela, Minna ^*, Parsons, Alun ^*, Västrik, Imre ^*, Siitonen, Sanna M., Porkka, Kimmo ^*, Wennerberg, Krister ^*, Heckman, Caroline A., Ettala, Pia ^*, Rimpiläinen, Johanna ^*, Siitonen, Timo ^*, Pyörälä, Marja ^*, Kuusanmäki, Heikki, Kontro, Mika ^*

Publikováno v: In Blood 15 November 2022 140 Supplement 1:2020-2022

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Ex VivoDrug Sensitivity Testing to Predict Response to Venetoclax + Azacitidine in Acute Myeloid Leukemia: Interim Results of the Prospective Multicenter Phase II Venex Trial

Autor: Kuusanmäki, Heikki, Kytölä, Sari, Vänttinen, Ida, Ranta, Amanda, Ruokoranta, Tanja, Holopainen, Annasofia, Koskela, Sirpa, Kuusisto, Milla E.L., Porkka, Kimmo, Räty, Riikka, Västrik, Imre, Wennerberg, Krister, Heckman, Caroline A., Ettala, Pia, Pyörälä, Marja, Rimpiläinen, Johanna, Siitonen, Timo, Kontro, Mika

Publikováno v: Blood; November 2021, Vol. 138 Issue: 1, Number 1 Supplement 1 p228-228, 1p

A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes.

Autor: Saliba-Gustafsson P; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; CardioMetabolic Unit at the Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.; Stanford Diabetes Research Center, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA., Justesen JM; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark., Ranta A; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA., Sharma D; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA., Bielczyk-Maczynska E; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA.; The Hormel Institute, University of Minnesota, MN, USA., Li J; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA., Najmi LA; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA., Apodaka M; University of the Basque Country (UPV/EHU), Faculty of Medicine and Nursing, Department of Physiology, Leioa, Spain., Aspichueta P; University of the Basque Country (UPV/EHU), Faculty of Medicine and Nursing, Department of Physiology, Leioa, Spain.; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, Instituto de Salud Carlos III)., Björck HM; Division of Cardiovascular Medicine, Centre for Molecular Medicine, Department of Medicine, Solna, Karolinska Inistitutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Eriksson P; Division of Cardiovascular Medicine, Centre for Molecular Medicine, Department of Medicine, Solna, Karolinska Inistitutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Franco-Cereceda A; Department of Molecular Medicine and Surgery, Karolinska Inistitutet, Stockholm, Sweden., Gloudemans M; Department of Pathology, Stanford University School of Medicine, CA, USA., Mujica E; Department of Immunology, Genetics and Pathology, Uppsala University, Sweden., den Hoed M; Department of Immunology, Genetics and Pathology, Uppsala University, Sweden., Assimes TL; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; VA Palo Alto Health Care System, Palo Alto CA, USA., Quertermous T; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark., Carcamo-Orive I; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain., Park CY; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA., Knowles JW; Department of Medicine, Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, CA, USA.; Stanford Prevention Research Center, Stanford, CA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Feb 04. Date of Electronic Publication: 2024 Feb 04.