Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ranjit Kumar Prajapati"'
Autor:
Jarmo Niemi, Kaisa Palmu, Keith Yamada, Mikko Metsä-Ketelä, Ranjit Kumar Prajapati, Petja Rosenqvist, Georgiy A. Belogurov, Pasi Virta
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Pseudouridimycin (PUM), a selective inhibitor of bacterial RNA polymerase has been previously detected in microbial-extracts of two strains of Streptomyces species (strain ID38640 and ID38673). Here, we isolated PUM and its deoxygenated analogue deso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc795e27ea1fb7108906b3fa37273fe
http://europepmc.org/articles/PMC6586884
http://europepmc.org/articles/PMC6586884
Publikováno v:
Journal of Biological Chemistry. 291:24029-24035
δ, a small protein found in most Gram-positive bacteria was, for a long time, thought to be a subunit of RNA polymerase (RNAP) and was shown to be involved in recycling of RNAP at the end of each round of transcription. However, how δ participates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f3e1ae6e71079dea5dd0725d731a4e
https://doi.org/10.1074/jbc.m116.746065
https://doi.org/10.1074/jbc.m116.746065
Publikováno v:
Journal of Biological Chemistry. 291:1064-1075
Most bacterial RNA polymerases (RNAP) contain five conserved subunits, viz. 2α, β, β′, and ω. However, in many Gram-positive bacteria, especially in fermicutes, RNAP is associated with an additional factor, called δ. For over three decades sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94dc75927ec61db8d02169f661d37f96
https://doi.org/10.1074/jbc.m115.686170
https://doi.org/10.1074/jbc.m115.686170
Publikováno v:
Journal of Biological Chemistry. 290:28575-28583
The transition from the formation of the RNA polymerase (RNAP)-promoter open complex step to the productive elongation complex step involves "promoter escape" of RNAP. From the structure of RNAP, a promoter escape model has been proposed that suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ded545d69c34b967f0ea644bc1e3659
https://doi.org/10.1074/jbc.m115.666008
https://doi.org/10.1074/jbc.m115.666008
Autor:
Jayanta Mukhopadhyay, Paulami Rudra, Ranjit Kumar Prajapati, Shreya Sengupta, Rajdeep Banerjee
Publikováno v:
Nucleic Acids Research
We propose a novel mechanism of gene regulation in Mycobacterium tuberculosis where the protein Rv1222 inhibits transcription by anchoring RNA polymerase (RNAP) onto DNA. In contrast to our existing knowledge that transcriptional repressors function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e6157e08fcc2804cfe68ef7b6879fe
https://pubmed.ncbi.nlm.nih.gov/25999340
https://pubmed.ncbi.nlm.nih.gov/25999340