Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ranjit Chauhan"'
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194612 (2018)
Protein myristoylation is a key protein modification carried out by N-Myristoyltransferase (NMT) after Methionine aminopeptidase 2 (MetAP2) removes methionine from the amino-terminus of the target protein. Protein myristoylation by NMT augments sever
Externí odkaz:
https://doaj.org/article/afc99b060c0a4ce8949a3bdee75ea91d
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004332 (2014)
Hepadnavirus at very low doses establishes in woodchucks asymptomatic, serologically undetectable but molecularly evident persistent infection. This primary occult infection (POI) preferentially engages the immune system and initiates virus-specific
Externí odkaz:
https://doaj.org/article/745ebdb7070d424e9af1b959f13d0984
Autor:
Annie Y Chen, Marija Zeremski, Ranjit Chauhan, Ira M Jacobson, Andrew H Talal, Tomasz I Michalak
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80078 (2013)
Resolution of chronic hepatitis C is considered when serum HCV RNA becomes repeatedly undetectable and liver enzymes normalize. However, long-term persistence of HCV following therapy with pegylated interferon-α/ribavirin (PegIFN/R) was reported whe
Externí odkaz:
https://doaj.org/article/d0108bd589ea4793a57961d877fc82a3
Publikováno v:
Antimicrob Agents Chemother
The hepatitis B virus (HBV) ribonuclease H (RNase H) is an attractive but unexploited drug target. Here, we addressed three limitations to the current state of RNase H inhibitor development: (a) Efficacy has been assessed only in transfected cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c6ed9e1ab4a4c6e65da497e5b8d9b3
https://pubmed.ncbi.nlm.nih.gov/34516242
https://pubmed.ncbi.nlm.nih.gov/34516242
Autor:
Yoshimi Shimizu, Takaji Wakita, Ranjit Chauhan, Koichi Watashi, Masayoshi Fukasawa, Tomasz I. Michalak
Publikováno v:
Cancer Genetics. :39-56
Integration of hepatitis B virus (HBV) DNA into host's genome is evident in all stages and models of HBV infection. Investigations of the initial virus-host junctions have been just recently initiated since their nature may promote liver oncogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a0ce3e9423949fdef969feb6293d36
https://doi.org/10.1016/j.cancergen.2019.04.060
https://doi.org/10.1016/j.cancergen.2019.04.060
Autor:
Ranjit Chauhan, Tomasz I. Michalak
Publikováno v:
Hepatoma Research. 2021
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435b263fdf128f4d85d8160ef6f9dffc
https://doi.org/10.20517/2394-5079.2020.136
https://doi.org/10.20517/2394-5079.2020.136
Autor:
Ashish Goyal, Ranjit Chauhan
Publikováno v:
Journal of Theoretical Biology. 455:269-280
Background Out of several phases of HBV infection, the least understood phase is occult hepatitis B virus infection. The paucity of data due to non-availability of biological tissues and the prerequisite of ultra-sensitive assays for the detection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b98c94e4c5c86f6bd0f90b9c0a6f14
https://doi.org/10.1016/j.jtbi.2018.06.020
https://doi.org/10.1016/j.jtbi.2018.06.020
Autor:
Tomasz I. Michalak, Sanjaya K. Satapathy, Jian Wu, Smruti R. Mohanty, Chiranjeevi Gadiparthi, Ranjit Chauhan, Nivedita Lahiri, Shilpa Lingala
Publikováno v:
World Journal of Hepatology
Chronic hepatitis B (CHB) is a major global health problem affecting an estimated 350 million people with more than 786000 individuals dying annually due to complications, such as cirrhosis, liver failure and hepatocellular carcinoma (HCC). Liver tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84e3cd3bf5476957ff5dd7a6740efe2
https://doi.org/10.4254/wjh.v10.i3.352
https://doi.org/10.4254/wjh.v10.i3.352
Autor:
John E. Tavis, Ranjit Chauhan
Publikováno v:
Gut. 71:233-234
Chronic hepatitis B virus (HBV) infection is maintained by the viral nuclear covalently closed circular DNA (cccDNA) that is the transcriptional template for HBV’s mRNAs. The cccDNA is durable during current therapies, but a functional cure for HBV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad51d89da1e373f48319fe629e293484
https://doi.org/10.1136/gutjnl-2021-324144
https://doi.org/10.1136/gutjnl-2021-324144
Autor:
Ranjit Chauhan, Tomasz I. Michalak
Publikováno v:
Cancer genetics. 244
Mechanism of initial hepatitis B virus (HBV) integrations and kinetics of DNA repair immediately after infection remain essentially unknown impairing understanding of hepadnaviral oncogenesis. WCM260 hepatocytes susceptible to HBV-compatible woodchuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64df4b87b63ec7a3135779283a95c493
https://pubmed.ncbi.nlm.nih.gov/32062411
https://pubmed.ncbi.nlm.nih.gov/32062411