Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Ranjit, Vijayan"'
Autor:
Latifa Alderei, Nouf Alshkeili, Dana Alnaqbi, Omar Abdulla Shehab, Ranjit Vijayan, Abdul-Kader Souid
Publikováno v:
Thalassemia Reports, Vol 14, Iss 2, Pp 44-48 (2024)
The mutation HBA2:c.*94A>G (AATAAA>AATAAG; rs63751269) is a 3′-UTR (3 prime untranslated region) single-nucleotide substitution in the polyadenylation (PA) signal of HBA2 (αPA:A→G). This pathogenic (CADD score, 14.92) variant is sporadic in the
Externí odkaz:
https://doaj.org/article/844d627203114d0ca9b9b8a7bd2b25fe
Autor:
Amie Jobe, Ranjit Vijayan
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
G protein-coupled receptors (GPCRs) make up the largest receptor superfamily, accounting for 4% of protein-coding genes. Despite the prevalence of such transmembrane receptors, a significant number remain orphans, lacking identified endogenous ligand
Externí odkaz:
https://doaj.org/article/5e0f40e4e0b84c3c94eb1f966f3ff330
Autor:
Mughair Abdul Aziz, Miloofer Sabeem, M. Sangeeta Kutty, Shafeeq Rahman, Maitha Khalfan Alneyadi, Alia Binghushoom Alkaabi, Eiman Saeed Almeqbali, Faical Brini, Ranjit Vijayan, Khaled Masmoudi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract In date palm, the LEA2 genes are of abundance with sixty-two members that are nearly all ubiquitous. However, their functions and interactions with potential target molecules are largely unexplored. In this study, five date palm LEA2 genes,
Externí odkaz:
https://doaj.org/article/b5f4e203ba034b089419588dea7f537c
Autor:
Shamsa Husain Ahmed Alhammadi, Bincy Baby, Priya Antony, Amie Jobe, Raghad Salman Mohammed Humaid, Fatema Jumaa Ahmed Alhammadi, Ranjit Vijayan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6529 (2024)
Mcl-1 (myeloid cell leukemia 1), a member of the Bcl-2 family, is upregulated in various types of cancer. Peptides representing the BH3 (Bcl-2 homology 3) region of pro-apoptotic proteins have been demonstrated to bind the hydrophobic groove of anti-
Externí odkaz:
https://doaj.org/article/87de8818e71b4420b6d53230f711ec12
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Hemorphins, short bioactive peptides produced by enzymatic cleavage of β-hemoglobin, exhibit antihypertensive properties by inhibiting angiotensin-1 converting enzyme (ACE1). ACE1 is a key player in the renin–angiotensin system (RAS) and
Externí odkaz:
https://doaj.org/article/3dcf70ae5cb34bcf81bd9f33863e446c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3059 (2024)
Type 2 diabetes is a chronic metabolic disorder characterized by high blood glucose levels due to either insufficient insulin production or ineffective utilization of insulin by the body. The enzyme dipeptidyl peptidase IV (DPP IV) plays a crucial ro
Externí odkaz:
https://doaj.org/article/56d229249f6643168902de8b7feb9d96
Autor:
Bincy Baby, Dhanya Vijay, Pretty S. Philip, Afra A. Alnuaimi, Hessa M. Almansoori, Sarah O. Areidat, Gulfaraz Khan, Ranjit Vijayan, M. Kalim Akhtar
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Vibrio is a genus of gram-negative, rod-shaped, motile bacteria commonly found in saltwater. One species in particular, Vibrio gazogenes PB1, sourced from an estuarine environment, is known to produce the secondary metabolite, prodigiosin. This high-
Externí odkaz:
https://doaj.org/article/fd9154418e804a68b82d9558d56f1543
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3217 (2023)
Methylmalonic aciduria and homocystinuria type C protein (MMACHC) is required by the body to metabolize cobalamin (Cbl). Due to its complex structure and cofactor forms, Cbl passes through an extensive series of absorptive and processing steps before
Externí odkaz:
https://doaj.org/article/efb193cde7d946cbaba58774f63f566e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Hemoglobin is one of the most widely studied proteins genetically, biochemically, and structurally. It is an oxygen carrying tetrameric protein that imparts the characteristic red color to blood. Each chain of hemoglobin harbors a heme group
Externí odkaz:
https://doaj.org/article/6f39e77497504ab5bc72c2528ed6caf6
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-9 (2022)
Abstract Background Hyalomma anatolicum is a widely distributed tick species that acts as a vector transmitting tick-borne pathogens (TBPs) in livestock. Such pathogens affect the health of livestock and consequently reduce their productivity. Knowle
Externí odkaz:
https://doaj.org/article/7c7eae89116742e4abc71a7368144721