Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ranjit, Bindra"'
Autor:
Jessica Nouws, Feng Wan, Eric Finnemore, Willy Roque, So-Jin Kim, Isabel Bazan, Chuan-xing Li, C. Magnus Skold, Qile Dai, Xiting Yan, Maurizio Chioccioli, Veronique Neumeister, Clemente J. Britto, Joann Sweasy, Ranjit Bindra, Åsa M. Wheelock, Jose L. Gomez, Naftali Kaminski, Patty J. Lee, Maor Sauler
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
The pathogenesis of chronic obstructive pulmonary disease (COPD) involves aberrant responses to cellular stress caused by chronic cigarette smoke (CS) exposure. However, not all smokers develop COPD and the critical mechanisms that regulate cellular
Externí odkaz:
https://doaj.org/article/6a424a974a7f439b9d1f5917c6975014
Autor:
Suzanne Xu, Allison Campbell, Veronica Chiang, Ranjit Bindra, Juan Vasquez, Farzana Pashankar
Publikováno v:
Pediatric Blood & Cancer. 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97731e3d967bc509abf59b1f5694d41e
https://doi.org/10.1002/pbc.30303
https://doi.org/10.1002/pbc.30303
Autor:
Julie J Miller, L Nicolas Gonzalez Castro, Samuel McBrayer, Michael Weller, Timothy Cloughesy, Jana Portnow, Ovidiu Andronesi, Jill S Barnholtz-Sloan, Brigitta G Baumert, Mitchell S Berger, Wenya Linda Bi, Ranjit Bindra, Daniel P Cahill, Susan M Chang, Joseph F Costello, Craig Horbinski, Raymond Y Huang, Robert B Jenkins, Keith L Ligon, Ingo K Mellinghoff, L Burt Nabors, Michael Platten, David A Reardon, Diana D Shi, David Schiff, Wolfgang Wick, Hai Yan, Andreas von Deimling, Martin van den Bent, William G Kaelin, Patrick Y Wen
Publikováno v:
Neuro-Oncology, 25(1), 4-25. Oxford University Press
Isocitrate dehydrogenase (IDH) mutant gliomas are the most common adult, malignant primary brain tumors diagnosed in patients younger than 50, constituting an important cause of morbidity and mortality. In recent years, there has been significant pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7888e20bfb658ca64d596b23bad01a7a
https://pure.eur.nl/en/publications/fbf82a24-927c-437d-a863-4c29db0953f1
https://pure.eur.nl/en/publications/fbf82a24-927c-437d-a863-4c29db0953f1
Publikováno v:
Biomed Chromatogr
Pamiparib (BGB-290) is an orally bioavailable, small molecule inhibitor of poly (ADP-ribose) polymerase 1 (PARP1) and PARP2. A reversed-phase LC with tandem mass spectrometry method was developed and fully validated for determining total and unbound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fdfe7fb2e3293e561b198337f34892
https://doi.org/10.1002/bmc.5478
https://doi.org/10.1002/bmc.5478
Pediatric GIST (gastrointestinal stromal tumors) are mostly KIT/ PDGFRA-WT and harbor mutations in SDH (succinate dehydrogenase), making them TKI (tyrosine kinase inhibitor) resistant due to the absence of gain-of-function tyrosine kinase mutations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a85d8b736d0d9180cf984b5b186ad43
https://doi.org/10.22541/au.165544424.41884113/v1
https://doi.org/10.22541/au.165544424.41884113/v1
Autor:
Joseph P, Eder, Deborah B, Doroshow, Khanh T, Do, Vicki L, Keedy, Jeffrey S, Sklar, Peter, Glazer, Ranjit, Bindra, Geoffrey I, Shapiro
Publikováno v:
JCO precision oncology. 5
Tumors with neomorphic mutations in IDH1/2 have defective homologous recombination repair, resulting in sensitivity to poly (ADP-ribose) polymerase (PARP) inhibition. The Olaparib Combination trial is a phase II, open-label study in which patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::177ac35c3f2f6ef8561450493e8b755e
https://pubmed.ncbi.nlm.nih.gov/35675574
https://pubmed.ncbi.nlm.nih.gov/35675574
Autor:
Elias Quijano, Diana Martinez Saucedo, Minsoo Khang, Yanfeng Liu, Dale Ludwig, Bruce C. Turner, Stephen Squinto, Ranjit Bindra, W. Mark Saltzman, Luisa Escobar-Hoyos, Peter M. Glazer
Publikováno v:
Cancer Research. 82:663-663
There is intense interest in the development of nucleic acid ligands for immune stimulation of the tumor microenvironment via pattern recognition receptors (PRRs), particularly for the treatment of “cold” tumors. However, delivery of these ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c7cc815ead759c3b78678595c9b4f9a
https://doi.org/10.1158/1538-7445.am2022-663
https://doi.org/10.1158/1538-7445.am2022-663
Autor:
Kristina Fanucci, Mary Josephine Paula Pilat, Ritu Shah, Scott Anthony Boerner, Jing Li, Diane E. Durecki, Jan Drappatz, Frances A. Collichio, Vinay K. Puduvalli, Frank S. Lieberman, Javier Gonzalez, Pierre Giglio, Xun Bao, S. Percy Ivy, Ranjit Bindra, Antonio Marcilio Padula Omuro, Patricia LoRusso
Publikováno v:
Journal of Clinical Oncology. 40:2035-2035
2035 Background: Isocitrate dehydrogenase ( IDH) 1 and IDH2 mutations ( IDH1/2mt) are the most common mutations in gliomas, occurring in over 70% of low grade and 20% of higher grade gliomas. IDH1/2mts are associated with improved prognosis, although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3d9fb6b27204f72d35c1991bf7cd36
https://doi.org/10.1200/jco.2022.40.16_suppl.2035
https://doi.org/10.1200/jco.2022.40.16_suppl.2035
Autor:
Jeffrey S. Sklar, Deborah B. Doroshow, Peter M. Glazer, Vicki L. Keedy, Khanh T. Do, Joseph Paul Eder, Geoffrey I. Shapiro, Ranjit Bindra
Publikováno v:
JCO Precis Oncol
PURPOSE Tumors with neomorphic mutations in IDH1/2 have defective homologous recombination repair, resulting in sensitivity to poly (ADP-ribose) polymerase (PARP) inhibition. The Olaparib Combination trial is a phase II, open-label study in which pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d691a50672162c42b9e5c237c257c7
https://europepmc.org/articles/PMC9848565/
https://europepmc.org/articles/PMC9848565/
Autor:
Jessica Nouws, Feng Wan, Eric Finnemore, Willy Roque, Sojin Kim, Isabel Bazan, Chuan-xing Li, C. Magnus Skold, Xiting Yan, Veronique Neumeister, Clemente J. Britto, Joann Sweasy, Ranjit Bindra, Åsa M. Wheelock, Jose Gomez-Villalobos, Naftali Kaminski, Patty J. Lee, Maor Sauler
Activation of the DNA damage response (DDR) due to chronic exposure to cigarette smoke (CS) is implicated in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). However, not all smokers develop COPD and the pathologic consequences of CS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c722d826fa9c8cbbe6124cca02bec300
https://doi.org/10.1101/2020.05.22.108688
https://doi.org/10.1101/2020.05.22.108688