Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ranjini Sundaram"'
Autor:
Rana Gbyli, Yuanbin Song, Wei Liu, Yimeng Gao, Giulia Biancon, Namrata S. Chandhok, Xiaman Wang, Xiaoying Fu, Amisha Patel, Ranjini Sundaram, Toma Tebaldi, Padmavathi Mamillapalli, Amer M. Zeidan, Richard A. Flavell, Thomas Prebet, Ranjit S. Bindra, Stephanie Halene
Publikováno v:
Leukemia. 36:1313-1323
Treatment options for patients with relapsed/refractory acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are scarce. Recurring mutations, such as mutations in isocitrate dehydrogenase-1 and -2 (IDH1/2) are found in subsets of AML and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f1f38a604d623f8f5eacc383216360
https://doi.org/10.1038/s41375-022-01536-x
https://doi.org/10.1038/s41375-022-01536-x
Autor:
Eric D. Huseman, Anna Lo, Olga Fedorova, Kingson Lin, Susan Gueble, Ranjini Sundaram, Anna M. Pyle, Ranjit S. Bindra, Seth Herzon
Publikováno v:
Cancer Research. 83:1568-1568
The DNA damage repair protein O6-methylguanine methyl transferase (MGMT) reverses O6-alkylguanine lesions via SN2 transfer of the alkyl lesion to an active site cysteine which restores DNA to its native state. MGMT is ubiquitously expressed in health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98b5c0e4d43c92c63598186dff779af0
https://doi.org/10.1158/1538-7445.am2023-1568
https://doi.org/10.1158/1538-7445.am2023-1568
Autor:
Daiki Ueno, Juan C. Vasquez, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Sam Friedman, Randy Caliliw, Shinji Ohtake, Xun Bao, Jing Li, Huihui Ye, Karla Boyd, Rong Rong Huang, Jack Dodson, Paul Boutros, Ranjit S. Bindra, Brian Shuch
Publikováno v:
Oncotarget, vol 13, iss 1
Loss-of-function mutations in genes encoding the Krebs cycle enzymes Fumarate Hydratase (FH) and Succinate Dehydrogenase (SDH) induce accumulation of fumarate and succinate, respectively and predispose patients to hereditary cancer syndromes includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bdace8f551663a705132bbe1be851c
https://escholarship.org/uc/item/3nj6b2ht
https://escholarship.org/uc/item/3nj6b2ht
Publikováno v:
Molecular Cancer Therapeutics. 20:P059-P059
Diffuse Intrinsic Pontine Glioma (DIPG) is a leading cause of death in pediatric cancer, with an abysmal Citation Format: Matthew A. Murray, Yazhe Wang, Ranjini Sundaram, Jason Beckta, Mark Saltzman, Ranjit Bindra. Exploiting mutant PPM1D-induced met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f52ba2e927bcfa26e39c722e3c379305
https://doi.org/10.1158/1535-7163.targ-21-p059
https://doi.org/10.1158/1535-7163.targ-21-p059
Autor:
Daiki Ueno, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Randy Caliliw, Huihui Ye, Rong Rong Huang, Jing Li, Karla Boyd, Ranjit S. Bindra, Juan C. Vasquez, Brian M. Shuch
Publikováno v:
Molecular Cancer Therapeutics. 20:P055-P055
Loss-of-function mutations in genes encoding the Krebs cycle enzymes fumarate hydratase (FH) and succinate dehydrogenase (SDH) lead to excess accumulation of fumarate and succinate, respectively. Germline mutations in FH lead to a genetic predisposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c564a9f8e91cfe714d857aea04856665
https://doi.org/10.1158/1535-7163.targ-21-p055
https://doi.org/10.1158/1535-7163.targ-21-p055
Autor:
Sophia Gayle, Juan Vasquez, Timothy Paradis, Kelli Jones, Ranjini Sundaram, Jinny van Doorn, Viswanathan Muthusamy, Ranjit S. Bindra, Robert J. Aiello, Vishwas Paralkar
Publikováno v:
Molecular Cancer Therapeutics. 20:P258-P258
Immune checkpoint blockade (ICB) in combination with chemotherapy is standard of care for several solid tumors. However, potent chemotherapies such as topoisomerase inhibitors can result in severe dose-limiting toxicities requiring dose reduction, li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11d668abff5a921bd243de2196e997ab
https://doi.org/10.1158/1535-7163.targ-21-p258
https://doi.org/10.1158/1535-7163.targ-21-p258
Publikováno v:
Thrombosis and Haemostasis. 82:88-92
SummaryTissue factor (TF) is a transmembrane glycoprotein that complexes with factor VIIa to initiate blood coagulation. It was reported in an earlier study that expression of high levels of TF in a human melanoma cell line promotes metastasis, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43edcae9873eb828931be67d965ed6d9
https://doi.org/10.1055/s-0037-1614634
https://doi.org/10.1055/s-0037-1614634
Publikováno v:
Molecular Neuroscience. 1:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92261512bd2416ed6dd8e5e44355aac2
https://doi.org/10.14259/mn.v1i1.106
https://doi.org/10.14259/mn.v1i1.106