E-NTPDase1/CD39 modulates renin release from heart mast cells during ischemia/reperfusion: a novel cardioprotective role

Autor: Ranjini Anand, Aaron J. Marcus, Alice Marino, Kengo Tomita, Silvia Aldi, Roberto Levi, Kim E. Olson, Federico Corti

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, no.1, p. 61-9 (2015)

Ischemia/reperfusion (I/R) elicits renin release from cardiac mast cells (MC), thus activating a local renin-angiotensin system (RAS), culminating in ventricular fibrillation. We hypothesized that in I/R, neurogenic ATP could degranulate juxtaposed M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d50057a009c5b1ac9154bcd2c6b80c2
https://pubmed.ncbi.nlm.nih.gov/25318477