Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ranjani, Rajapaksa"'
Autor:
Stefano Testa, Ole A. W. Haabeth, Timothy R. Blake, Trevor J. Del Castillo, Debra K. Czerwinski, Ranjani Rajapaksa, Paul A. Wender, Robert M. Waymouth, Ronald Levy
Publikováno v:
Biomacromolecules
Charge-altering releasable transporters (CARTs) are a class of oligonucleotide delivery vehicles shown to be effective for delivery of messenger RNA (mRNA) both in vitro and in vivo. Here, we exploited the chemical versatility of the CART synthesis t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca1a91d7d1e7a5448de07c5b4b68f26
https://doi.org/10.1021/acs.biomac.2c00469
https://doi.org/10.1021/acs.biomac.2c00469
Autor:
Shoshana Levy, Ronald Levy, Chiung-Chi Kuo, Aurelien Marabelle, Minu K. Srivastava, Ranjani Rajapaksa, Felipe Vences-Catalán
Supplementary Table 1: Antibodies used in this study. Supplementary Figure 1: CD81 expression on tumor cell lines. Supplementary Figure 2: Analysis of purified CD4+CD25+ Tregs for FoxP3 expression. Supplementary Figure 3: Tregs from LLC and E0771 tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e20b682aa48d30db88b6810e43833d
https://doi.org/10.1158/0008-5472.22405815.v1
https://doi.org/10.1158/0008-5472.22405815.v1
Autor:
Anderson Lee, Felipe Vences-Catalán, Caitlyn L. Miller, Ranjani Rajapaksa, Chiung-Chi Kuo, Vishnu C. Ramani, Stefanie S. Jeffrey, Shoshana Levy, Ronald Levy
Publikováno v:
Proc Natl Acad Sci U S A
Tetraspanins are an evolutionary conserved family of proteins involved in multiple aspects of cell physiology, including proliferation, migration and invasion, protein trafficking, and signal transduction; yet their detailed mechanism of action is un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb73589e06f2eee16bc9632ff49b46e
https://europepmc.org/articles/PMC8214710/
https://europepmc.org/articles/PMC8214710/
Autor:
Ranjani Rajapaksa, Shoshana Levy, Caroline Duault, Ronald Levy, Noemi Andor, Debra K. Czerwinski, Felipe Vences-Catalán, Chiung-Chi Kuo
Publikováno v:
The Journal of Experimental Medicine
The anti-CD81 mAb (5A6) eliminates lymphoma tumor cells from patient follicular biopsy specimens while sparing the imbedded normal B and T lymphocytes. It has equivalent therapeutic effects as rituximab against a xenografted human B cell lymphoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2bb364d2b5f1153d422fd123794983
http://europepmc.org/articles/PMC6605745
http://europepmc.org/articles/PMC6605745
Autor:
Caroline Duault, Ronald Levy, Felipe Vences-Catalán, Shoshana Levy, Ranjani Rajapaksa, Chiung-Chi Kuo
Publikováno v:
Biochemical Society Transactions. 45:531-535
CD81 participates in a variety of important cellular processes such as membrane organization, protein trafficking, cellular fusion and cell–cell interactions. In the immune system, CD81 regulates immune synapse, receptor clustering and signaling; i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6671b8c681035bb0e33eb316e21c346a
https://doi.org/10.1042/bst20160478
https://doi.org/10.1042/bst20160478
Publikováno v:
Immunology. 137:48-55
In B lymphocytes, the cell surface receptor CD38 is involved in apoptosis of immature B cells, proliferation and differentiation of mature B cells. Although CD38 has been establish as a receptor, its signaling has been only partially characterized. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff6a4204390520748261344e6ea580a
https://doi.org/10.1111/j.1365-2567.2012.03602.x
https://doi.org/10.1111/j.1365-2567.2012.03602.x
Autor:
Shoshana Levy, Matthew J. Goldstein, Ranjani Rajapaksa, Bindu Varghese, Debra K. Czerwinski, Joshua Brody, Ronald Levy, Holbrook E Kohrt
Publikováno v:
Blood. 117:118-127
We designed a whole tumor cell vaccine by “loading” lymphoma tumor cells with CG-enriched oligodeoxynucleotide (CpG), a ligand for the Toll-like receptor 9 (TLR9). CpG-loaded tumor cells were phagocytosed, delivering both tumor antigen(s) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bf457e0b2fe75cbe135325c96a5eb2
https://doi.org/10.1182/blood-2010-06-288456
https://doi.org/10.1182/blood-2010-06-288456
Autor:
Shoshana Levy, Felipe Vences-Catalán, Chiung-Chi Kuo, Ronald Levy, Minu K. Srivastava, Aurélien Marabelle, Ranjani Rajapaksa
Publikováno v:
Cancer research. 75(21)
Tumor cells counteract innate and adaptive antitumor immune responses by recruiting regulatory T cells (Treg) and innate myeloid-derived suppressor cells (MDSC), which facilitate immune escape and metastatic dissemination. Here we report a role in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d72795e88786cc1de02c29d2eacf749
https://pubmed.ncbi.nlm.nih.gov/26329536
https://pubmed.ncbi.nlm.nih.gov/26329536
Publikováno v:
Molecular and Cellular Biology. 26:1373-1385
The tetraspanin web is composed of a network of tetraspanins and their partner proteins that facilitate cellular interactions and fusion events by an unknown mechanism. Our aim was to unravel the web partnership between the tetraspanin CD81 and CD19,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aeae6d3363e352b3f26fa40a545f1d
https://doi.org/10.1128/mcb.26.4.1373-1385.2006
https://doi.org/10.1128/mcb.26.4.1373-1385.2006
Publikováno v:
Blood. 101:433-440
We have cloned and characterized a novel human gene,HGAL (human germinal center–associated lymphoma), which predicts outcome in patients with diffuse large B-cell lymphoma (DLBCL). The HGAL gene comprises 6 exons and encodes a cytoplasmic protein o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e564596eeea256618f6a4876ce8517d
https://doi.org/10.1182/blood-2002-06-1931
https://doi.org/10.1182/blood-2002-06-1931