Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ranjana Chakravarthy"'
Publikováno v:
Therapeutic Innovation & Regulatory Science. 50:759-768
With available funding from the public sector decreasing while medical needs and scientific complexity increase, private-sector collaborations with academia and government have become increasingly key in furthering medical innovation. Nonetheless, so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9e2426972c9eb19dbeeb3265d4067e
https://doi.org/10.1177/2168479016648730
https://doi.org/10.1177/2168479016648730
Autor:
Joseph A. DiMasi, Ranjana Chakravarthy
Publikováno v:
Clinical Pharmacology & Therapeutics. 100:754-760
We examined data on the entry rates of second and later entrants in 43 pharmacologic classes, as well as the timing of patent filings and development milestones for 79 later-in-class drugs. The median time to when a second entrant was approved was 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ca58c27b11ca8799c606bf28d25715
https://doi.org/10.1002/cpt.502
https://doi.org/10.1002/cpt.502
Publikováno v:
Personalized Medicine. 13:337-345
Four challenges to the adoption of personalized medicine were identified in the mid-2000s – adherence to the blockbuster model, the lack of a supportive regulatory environment, the dysfunctional payment system and physician barriers. In this articl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbfed9dc39625df4ab6e972d7c3088a
https://doi.org/10.2217/pme-2016-0011
https://doi.org/10.2217/pme-2016-0011
Publikováno v:
Clinical Therapeutics. 37:1852-1858
Purpose Meeting marketplace demands for proving the value of new products requires more data than the industry has routinely produced. These data include evidence from comparative effectiveness research (CER), including randomized, controlled trials;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d74e44c15a5e53587239276b396b91
https://doi.org/10.1016/j.clinthera.2015.05.514
https://doi.org/10.1016/j.clinthera.2015.05.514
Publikováno v:
Nature reviews. Drug discovery. 16(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d54b94b656559e211759e6c1173d4263
https://pubmed.ncbi.nlm.nih.gov/28473728
https://pubmed.ncbi.nlm.nih.gov/28473728
Publikováno v:
Nature reviews. Drug discovery. 15(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af95d7868d2a3c64413d82f48a60568d
https://pubmed.ncbi.nlm.nih.gov/27765941
https://pubmed.ncbi.nlm.nih.gov/27765941
Publikováno v:
Nature reviews. Drug discovery. 14(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d5ae9a37213995e75091b68a7bf3c1a
https://pubmed.ncbi.nlm.nih.gov/26471367
https://pubmed.ncbi.nlm.nih.gov/26471367
Publikováno v:
BMJ (Clinical research ed.). 351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8db7e4f06f536a33fe6ec572c5658973
https://pubmed.ncbi.nlm.nih.gov/26141315
https://pubmed.ncbi.nlm.nih.gov/26141315
Publikováno v:
Nature Reviews Drug Discovery. 15:739-740
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::116c790a111a8b90859c74ee4d373e58
https://doi.org/10.1038/nrd.2016.200
https://doi.org/10.1038/nrd.2016.200
Publikováno v:
Nature Reviews Drug Discovery. 16:448-448
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2697948012e328f230d289847ee81b3f
https://doi.org/10.1038/nrd.2017.80
https://doi.org/10.1038/nrd.2017.80