Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ranjan Jagath Rajapakse"'
Autor:
Wesley K. M. Chong, Steele Rebecca, Francesca Benedini, Alessandro Cecchi, Ranjan Jagath Rajapakse, Stefano Biondi, Claudia Temperini, Daniela Miglietta, Claudiu T. Supuran, Laura Carzaniga, Valentina Borghi, Francesco Impagnatiello
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6565-6570
Novel bi-functional compounds with a nitric oxide (NO)-releasing moiety bound to a dorzolamide scaffold were investigated. Several compounds were synthesized and their activity as selective carbonic anhydrase inhibitors (CAI) evaluated in vitro on re
Autor:
Jennifer Lafontaine, Ping Chen, Quyen-Quyen T. Do, Karen Siegel, Lilian Y. Li, Paul S. Humphries, David M. Wilhite, Tianlun Wang, Charles S. Agree, David Alexander, Sergei Timofeevski, Ranjan Jagath Rajapakse, Elizabeth A. Lunney
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(8)
The development of a series of novel 4-substituted-2-aminopyrimidines as inhibitors of c-Jun N-terminal kinases is described. The synthesis, in vitro inhibitory values for JNK1, and the in vitro inhibitory value for a c-Jun cellular assay are discuss
Autor:
Ved P. Pathak, Christie Lance Christopher, Mark C. Guzman, Mark B. Anderson, Haitao Li, Ranjan Jagath Rajapakse, Alex K. Rabinovich, Stella Tsank, Wayne D. Kornreich, Thomas Goetzen, Larry K. Truesdale, Haresh N. Vazir, Scott A. Shackelford, Martha A. Hananel
Publikováno v:
The Journal of Organic Chemistry. 68:2986-2986
A new one-pot nitration employing tetramethylammonium nitrate and trifluoromethanesulfonic anhydride in dichloromethane to provide a ready source of the nitronium triflate nitrating agent is presented. Rapid and selective nitration with a variety of