Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Rania Soudy"'
Autor:
Rania Soudy, Ryoichi Kimura, Aarti Patel, Wen Fu, Kamaljit Kaur, David Westaway, Jing Yang, Jack Jhamandas
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/3654b8933c2a4e488728abfc7f4098ef
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Extracellular vesicles (EVs) are double membrane structures released by all cell types with identified roles in the generation, transportation, and degradation of amyloid-β protein (Aβ) oligomers in Alzheimer’s disease (AD). EVs are thus increasi
Externí odkaz:
https://doaj.org/article/c8e10a580cea4e278ea7bc37b0f8690f
Autor:
Wen Fu, Vlatka Vukojevic, Aarti Patel, Rania Soudy, David MacTavish, David Westaway, Kamaljit Kaur, Valeri Goncharuk, Jack Jhamandas
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-12 (2017)
Abstract Background Neuroinflammation in the brain consequent to activation of microglia is viewed as an important component of Alzheimer’s disease (AD) pathology. Amyloid beta (Aβ) protein is known to activate microglia and unleash an inflammator
Externí odkaz:
https://doaj.org/article/9a9fa02c523c4fa99cf9b49d41312e22
Autor:
Waleed Mohammed-Saeid, Rania Soudy, Richa Tikoo, Kamaljit Kaur, Ronald E Verrall, Ildiko Badea
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
Purpose Achieving successful gene therapy requires delivery of a gene vector specifically to the targeted tissue with efficient expression and a good safety profile. The objective of this work was to develop, characterize and determine if a novel gem
Externí odkaz:
https://doaj.org/article/00b3c5f6be054d2d97e5c23064ca9143
Autor:
Hanna Trzeciakiewicz, Jose Esteves-Villanueva, Rania Soudy, Kamaljit Kaur, Sanela Martic-Milne
Publikováno v:
Sensors, Vol 15, Iss 8, Pp 19429-19442 (2015)
The adsorption of the proteins CD13, mucin and bovine serum albumin on VLGXE-Au and YNGRT-Au interfaces was monitored by electrochemical impedance spectroscopy in the presence of [Fe(CN)6]3−/4−. The hydrophobicity of the Au surface was tailored u
Externí odkaz:
https://doaj.org/article/8509a0626ed94080b74331585a5143a8
Autor:
Hoda Soleymani Abyaneh, Amir Hassan Soleimani, Mohammad Reza Vakili, Rania Soudy, Kamaljit Kaur, Francesco Cuda, Ali Tavassoli, Afsaneh Lavasanifar
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 196 (2018)
Hypoxia can induce chemoresistance, which is a significant clinical obstacle in cancer therapy. Here, we assessed development of hypoxia-induced chemoresistance (HICR) against free versus polymeric cisplatin micelles in a triple negative breast cance
Externí odkaz:
https://doaj.org/article/e9afad8d0ea84580a99590b31667717d
Short amylin receptor antagonist peptides improve memory deficits in Alzheimer’s disease mouse model
Autor:
Aarti Patel, Jack H. Jhamandas, Ryoichi Kimura, Wen Fu, Rania Soudy, Kamaljit Kaur, David Westaway, Jing Yang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Recent evidence supports involvement of amylin and the amylin receptor in the pathogenesis of Alzheimer’s disease (AD). We have previously shown that amylin receptor antagonist, AC253, improves spatial memory in AD mouse models. Herein, we generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1e85264f3bbf1d6c26febbc9e56711
http://link.springer.com/article/10.1038/s41598-019-47255-9
http://link.springer.com/article/10.1038/s41598-019-47255-9
Autor:
Wen Fu, Jack H. Jhamandas, Rania Soudy, Rachel A Davey, Jing Yang, Ryoichi Kimura, Jeffrey D Zajac, Aarti Patel, David Westaway, David MacTavish
Publikováno v:
Molecular Neurobiology
Based upon its interactions with amyloid β peptide (Aβ), the amylin receptor, a class B G protein-coupled receptor (GPCR), is a potential modulator of Alzheimer’s disease (AD) pathogenesis. However, past pharmacological approaches have failed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6440906649361b0bae4fb8ede6397c
https://doi.org/10.21203/rs.3.rs-515476/v1
https://doi.org/10.21203/rs.3.rs-515476/v1
Autor:
Ronald E. Verrall, Richa Tikoo, Waleed Mohammed-Saeid, Kamaljit Kaur, Rania Soudy, Ildiko Badea
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
Purpose Achieving successful gene therapy requires delivery of a gene vector specifically to the targeted tissue with efficient expression and a good safety profile. The objective of this work was to develop, characterize and determine if a novel gem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fafcf41b069f3148c644ac3fa51d6d65
https://doi.org/10.18433/jpps30010
https://doi.org/10.18433/jpps30010
Publikováno v:
Trends in Molecular Medicine. 23:709-720
Alzheimer'sdisease (AD) is a progressive neurodegenerative disorder, characterized by senile plaques constituting extracellular deposits of β-amyloid (Aβ) fibrils. Since Aβ accumulation in the brain is considered an early event preceding, by decad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b580439c8ddffbdff96dae54ae0565f
https://doi.org/10.1016/j.molmed.2017.06.003
https://doi.org/10.1016/j.molmed.2017.06.003