Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rania M. Salama"'
Autor:
Rania M. Salama, Nermin Eissa, Ahmed S. Doghish, Ahmed I. Abulsoud, Nourhan M. Abdelmaksoud, Osama A. Mohammed, Sherif S. Abdel Mageed, Samar F. Darwish
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
MicroRNAs (miRNAs) are short RNA molecules that are not involved in coding for proteins. They have a significant function in regulating gene expression after the process of transcription. Their participation in several biological processes has render
Externí odkaz:
https://doaj.org/article/e4390667e2024f2e89ac89c4c73c8d22
Autor:
Samar F. Darwish, Abdullah M. M. Elbadry, Amir S. Elbokhomy, Ghidaa A. Salama, Rania M. Salama
Publikováno v:
Frontiers in Aging, Vol 4 (2023)
The pathophysiology of different neurodegenerative illnesses is significantly influenced by the polarization regulation of microglia and macrophages. Traditional classifications of macrophage phenotypes include the pro-inflammatory M1 and the anti-in
Externí odkaz:
https://doaj.org/article/7092816bc26a44028869dea3e8ff6ddd
Autor:
Azza H. Abdelwahab, Amira M. Negm, Eman S. Mahmoud, Rania M. Salama, Mona F. Schaalan, Azza A. K. El-Sheikh, Basma K. Ramadan
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Fast food is a major risk factor for atherosclerosis, a leading cause of morbidity and mortality in the Western world. Apelin, the endogenous adipokine, can protect against cardiovascular disease via activating its receptor, APJ. Concur
Externí odkaz:
https://doaj.org/article/d58db3d7c4604ae9bf2b53880cf2d1f1
Autor:
Rania M. Salama, Samah S. Abbas, Samar F. Darwish, Al Aliaa Sallam, Noura F. Elmongy, Sara A. El Wakeel
Publikováno v:
Archives of Pharmacal Research. 46:323-338
Alcoholic liver disease (ALD) refers to hepatic ailments induced by excessive alcohol intake. The pathogenesis of ALD comprises a complex interplay between various mechanistic pathways, among which inflammation and oxidative stress are key players. B
Autor:
Nada S Hamed, Abdelkader M Mohamed, Rania M. Salama, Amira S NourelDeen, Raneem M Ata, Mohamed A Hassan
Publikováno v:
Toxicol Res (Camb)
Cyclophosphamide (CP) is one of the most potent alkylating agents and is widely used in the treatment of numerous neoplastic conditions, autoimmune diseases and following organ transplantation. Due to its ability to induce oxidative stress and subseq
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 111, Iss, Pp 714-723 (2019)
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases in which the phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/protein kinase B (PKB or Akt) pathway is deregulated in response to phosphatase and tensin homolog (PTEN)
Autor:
Rania M. Salama, Samar F. Darwish, Ismail El Shaffei, Noura F. Elmongy, Nouran M. Fahmy, Manal S. Afifi, Ghada A. Abdel-Latif
Publikováno v:
Food and Chemical Toxicology. 165:113146
Nod-like receptor pyrin domain-1 containing 3 (NLRP3) inflammasome/tumor necrosis factor alpha (TNFα)/nuclear factor kappa B (NFκB) inflammatory pathway is known to be involved in the pathogenesis of ulcerative colitis (UC). Inversely, miRNA-223 ca
Autor:
Doaa Boshra Farag, Mona F. Schaalan, Ghada A. Abdel-Latif, Ismail El Shaffei, Rania M. Salama
Publikováno v:
Journal of biochemical and molecular toxicologyREFERENCES. 35(6)
The anticancer agent, cisplatin (CIS), is associated with hepatotoxic effects related to activation of oxidative stress and inflammation pathways. CIS-induced oxidative DNA damage reduces sirtuin 1 (SIRT1) activity, which in turn, modulates the activ
Tumor necrosis factor receptor (TNFR) activation and nuclear factor kappa B (NFκB) expression play a significant role in the activation of nod-like receptor pyrin domain-1 containing 3 (NLRP3) inflammasome inflammatory pathway, which is involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b0b614ea76f6d39eb1c4fa977a65cd
https://doi.org/10.1101/2020.12.22.423927
https://doi.org/10.1101/2020.12.22.423927
Autor:
Rania M. Salama, Merihane M Nasr, Jannatullah I Abdelhakeem, Mohamed A ElGamal, Omar K Roshdy
Publikováno v:
Drug and chemical toxicology. 45(3)
Cyclophosphamide (CP) is widely used as a chemotherapy against various types of cancers. However, CP is accompanied with multiple organ toxicity due to production of reactive oxygen species (ROS), induction of inflammation and consequently apoptosis.