Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rania M. El Sayed"'
Autor:
Ayman Saad, Mohey Eldin M. El Shikh, Eglal A. Ghoneimy, Rania M. El Sayed, Hussin H. El Shikh, Ahmed M. Hashem, Hanaa Y. Ahmed, Ahmed M. Ragab
Publikováno v:
Current Cancer Therapy Reviews. 6:222-228
Autor:
Daniel H. Conrad, Rania M. El Sayed, Howard C. Crawford, Peter J. Dempsey, Mohey Eldin M. El Shikh, David R. Gibb, Joanna Cichy, Hideo Yagita, Dae Joong Kang, John G. Tew, Warren J. Rowe
Publikováno v:
The Journal of Experimental Medicine
The proteolytic activity of a disintegrin and metalloproteinase 10 (ADAM10) regulates cell-fate decisions in Drosophila and mouse embryos. However, in utero lethality of ADAM10−/− mice has prevented examination of ADAM10 cleavage events in lympho
Autor:
Mohey Eldin M. El Shikh, Al M. Best, Rania M. El Sayed, Yongzhong Wu, Andras K. Szakal, John G. Tew
Publikováno v:
International Immunology. 21:745-756
Reports that follicular dendritic cells (FDCs) produce IL-6 prompted the hypotheses that immune complexes (ICs) induce FDCs to produce IL-6 and that FDC–IL-6 promotes germinal center (GC) reactions, somatic hypermutation (SHM) and IgG production. F
Autor:
Costantino Pitzalis, Andras K. Szakal, Yaseer Majeed, Vivienne Moradi, Rania M. El Sayed, Masoud H. Manjili, Piruthivi Sukumar, Michael Burnet, Sinead Harney, Michael Seed, Anne English, Paul Emery, Jacqueline Naylor, Mohey Eldin M. El Shikh, Noel M. Caplice, Fergus Shanahan, Georg Schett, David J. Beech, Margaret Lees, Grainne Murphy, Wolfgang Albrecht, Coziana Ciurtin, Michael G. Molloy, Nasser M Malik, Maciej Kmieciak, John J. Ryan, Stefan Laufer, John G. Tew
Publikováno v:
Rheumatology. 50:iii50-iii52
Publikováno v:
Developmental Biology of Peripheral Lymphoid Organs ISBN: 9783642144288
Immunosenescence occurs after maturation and is expressed as a series of failing immunologic functions. Aging is best studied in the peripheral organs of the immune system such as lymph nodes, spleen, and isolated lymphoid tissues. The functional imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dc4d2a6887c31ea9b4336ed3634431f
https://doi.org/10.1007/978-3-642-14429-5_13
https://doi.org/10.1007/978-3-642-14429-5_13
Autor:
Rania M. El Sayed, John G. Tew, Mohey Eldin M. El Shikh, Andras K. Szakal, Selvakumar Sukumar
A need for antigen-processing and presentation to B cells is not widely appreciated. However, cross-linking of multiple B cell receptors (BCRs) by T-independent antigens delivers a potent signal that induces antibody responses. Such BCR cross-linking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230a199219dc88a56aecc71c2bfc0703
https://europepmc.org/articles/PMC2886728/
https://europepmc.org/articles/PMC2886728/
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(6)
Follicular dendritic cells (FDCs) periodically arrange membrane-bound immune complexes (ICs) of T-dependent Ags 200–500Å apart, and in addition to Ag, they provide B cells with costimulatory signals. This prompted the hypothesis that Ag in FDC-IC
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(7)
Microbial molecular patterns engage TLRs and activate dendritic cells and other accessory cells. Follicular dendritic cells (FDCs) exist in resting and activated states, but are activated in germinal centers, where they provide accessory function. We
Publikováno v:
European journal of immunology. 36(10)
Follicular dendritic cell (FDC)-FcgammaRIIB levels are up-regulated 1-3 days after challenge of actively immunized mice with Ag. This kinetics suggested that memory cells are not driving this response, prompting the hypothesis that immune complex (IC
Autor:
Pier Luigi Meroni, Costantino Pitzalis, Masoud H. Manjili, Maciej Kmieciak, Mohey Eldin M. El Shikh, Martina Biggioggero, Andras K. Szakal, Rania M. El Sayed, John G. Tew
Publikováno v:
Annals of the Rheumatic Diseases. 71:A38.1-A38
Backgroundand objectives Follicular dendritic cells (FDCs) are characteristic components of organised tertiary lymphoid structures (TLS) containing germinal centres (GCs) in chronically inflamed tissues. However, the role of FDCs in initiation, maint