Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rania Dayoub"'
Autor:
Katharina Schilcher, Rania Dayoub, Marion Kubitza, Jakob Riepl, Kathrin Klein, Christa Buechler, Michael Melter, Thomas S. Weiss
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13222 (2023)
Metabolic dysfunction-associated steatotic liver disease (MASLD) comprises a spectrum of liver diseases, ranging from liver steatosis to metabolic dysfunction-associated steatohepatitis (MASH), increasing the risk of developing cirrhosis and hepatoce
Externí odkaz:
https://doaj.org/article/f66b909cda2343778909fc110ea49559
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8107 (2023)
Inflammasomes and innate immune cells have been shown to contribute to liver injury, thereby activating Kupffer cells, which release several cytokines, including IL-6, IL-1ß, and TNFα. Augmenter of liver regeneration (ALR) is a hepatotropic co-mito
Externí odkaz:
https://doaj.org/article/4d3bf5e31d12455790ab2c3cb3ef28f3
Autor:
Thomas S. Weiss, Madeleine Lupke, Rania Dayoub, Edward K. Geissler, Hans J. Schlitt, Michael Melter, Elke Eggenhofer
Publikováno v:
Cells, Vol 8, Iss 11, p 1421 (2019)
Hepatic ischemia reperfusion injury (IRI) is a major complication in liver resection and transplantation. Here, we analyzed the impact of recombinant human augmenter of liver regeneration (rALR), an anti-oxidative and anti-apoptotic protein, on the d
Externí odkaz:
https://doaj.org/article/dde49258cd05424985df59eddbd45c90
Autor:
Thomas Klag, Maria Thomas, Dirk Ehmann, Lioba Courth, Daniela Mailänder-Sanchez, Thomas S. Weiss, Rania Dayoub, Kerstin Abshagen, Brigitte Vollmar, Wolfgang E. Thasler, Eduard F. Stange, Christoph P. Berg, Nisar P. Malek, Ulrich M. Zanger, Jan Wehkamp
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background & aimsKnowledge about innate antimicrobial defense of the liver is limited. We investigated hepatic expression and regulation of antimicrobial peptides with focus on the human beta defensin-1 (hBD-1).MethodsRadial diffusion assay was used
Externí odkaz:
https://doaj.org/article/758afb4f1b044c01a3cc3e8ddec592b7
Autor:
Thomas S Weiss, Madeleine Lupke, Sara Ibrahim, Christa Buechler, Julia Lorenz, Petra Ruemmele, Ute Hofmann, Michael Melter, Rania Dayoub
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184282 (2017)
Nonalcoholic fatty liver disease (NAFLD) covers a spectrum from simple steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis. Free fatty acids (FFA) induce steatosis and lipo-toxicity and correlate with severity of NAFLD. In this study we ai
Externí odkaz:
https://doaj.org/article/bbfc633ae3f54655902577ae874dff0c
Autor:
Savneet Kaur, Preety Rawal, Hamda Siddiqui, Sumati Rohilla, Shvetank Sharma, Dinesh M Tripathi, Sukriti Baweja, Mohsin Hassan, Sebastian Vlaic, Reinhard Guthke, Maria Thomas, Rania Dayoub, Chaggan Bihari, Shiv K. Sarin, Thomas S. Weiss
Publikováno v:
Cells, Vol 8, Iss 10, p 1277 (2019)
Given the important role of angiogenesis in liver pathology, the current study investigated the role of Runt-related transcription factor 1 (RUNX1), a regulator of developmental angiogenesis, in the pathogenesis of non-alcoholic steatohepatitis (NASH
Externí odkaz:
https://doaj.org/article/cf2ced4ce6784c1e853a3a3eedbd69a9
Autor:
Rania Dayoub, Arndt Vogel, Jutta Schuett, Madeleine Lupke, Susannah M. Spieker, Nadja Kettern, Eberhard Hildt, Michael Melter, Thomas S. Weiss
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 237-244 (2013)
Abstract Liver regeneration can be impaired by permanent oxidative stress and activation of nuclear factor erythroid 2-related factor 2 (Nrf2), known to regulate the cellular antioxidant response, and has been shown to improve the process of liver re
Externí odkaz:
https://doaj.org/article/bc96681355344ea08af8bdf850d1242e
Publikováno v:
Zeitschrift für Gastroenterologie.
Publikováno v:
Zeitschrift für Gastroenterologie.
Autor:
Thomas S, Weiss, Rania, Dayoub
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1506
In response to liver injury, hepatic cells, especially hepatocytes, can rapidly proliferate to repair liver damage. Additionally, it was shown that under certain circumstances liver resident cells with progenitor capabilities are involved in liver ce