Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rania Abu El‐Asrar"'
Autor:
Michiel Vanmeert, Hannu Myllykallio, Rania Abu El‐Asrar, Jiahong Li, Eveline Lescrinier, Anastasia Parchina, Lia Margamuljana, Hubert F. Becker, Shrinivas Dumbre, Jakub Modranka, Hoai Nguyen, Roeland Vanhoutte, Mayla Salman, Jef Rozenski, Steven De Jonghe, Piet André Maurits Maria Herdewijn
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2019, 14 (6), pp.645-662. ⟨10.1002/cmdc.201800739⟩
ChemMedChem, Wiley-VCH Verlag, 2019, 14 (6), pp.645-662. ⟨10.1002/cmdc.201800739⟩
Since the discovery of a flavin‐dependent thymidylate synthase (ThyX or FDTS) that is absent in humans but crucial for DNA biosynthesis in a diverse group of pathogens, the enzyme has been pursued for the development of new antibacterial agents aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bad860f52246e3df6dbc18d33e50352
https://doi.org/10.1002/cmdc.201800739
https://doi.org/10.1002/cmdc.201800739
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:1778-1785
As part of a selection strategy for artificial nucleic acids (XNA) (to be considered as potential new information systems in vivo), we have carried out a modelling study on cyclohexanyl nucleic acids (CNA) duplexes and hairpins. CNA may form a duplex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56c087263a06bf8d1cfe43123186ef9
https://doi.org/10.1016/j.bmc.2016.03.007
https://doi.org/10.1016/j.bmc.2016.03.007
Autor:
Mikhail Abramov, Rania Abu el Asrar, Omprakash Bande, Stefano Agnello, Lia Margamuljana, Piet Herdewijn, Mi-Yeon Jang
Publikováno v:
Chembiochem : a European journal of chemical biology. 18(24)
A series of nucleotide analogues, with a hypoxanthine base moiety (8-aminohypoxanthine, 1-methyl-8-aminohypoxanthine, and 8-oxohypoxanthine), together with 5-methylisocytosine were tested as potential pairing partners of N8-glyco sylated nucleotides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70603e5345b9ee44ae5e3e9b4b0cb4b1
https://pubmed.ncbi.nlm.nih.gov/29024251
https://pubmed.ncbi.nlm.nih.gov/29024251
Autor:
Sergey N. Kochetkov, L. A. Alexandrova, Rania Abu El-asrar, Vladimir O. Chekhov, Piet Herdewijn, Eduard R. Shmalenyuk
Publikováno v:
Bioorganicmedicinal chemistry. 23(22)
A series of 5'-monophosphates of 5-substituted 2'-deoxyuridine analogs, which recently demonstrated in vitro substantial suppression of two strains of Mycobacterium tuberculosis growth (virulent laboratory H37Rv and multiple resistant MS-115), has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d926a93ea5256f2f5d2cff806a68dd
https://pubmed.ncbi.nlm.nih.gov/26482569
https://pubmed.ncbi.nlm.nih.gov/26482569
Publikováno v:
ChemBioChem
ChemBioChem, 2012, 13 (16), pp.2439-2444. ⟨10.1002/cbic.201200413⟩
ChemBioChem, Wiley-VCH Verlag, 2012, 13 (16), pp.2439-2444. ⟨10.1002/cbic.201200413⟩
ChemBioChem, 2012, 13 (16), pp.2439-2444. ⟨10.1002/cbic.201200413⟩
ChemBioChem, Wiley-VCH Verlag, 2012, 13 (16), pp.2439-2444. ⟨10.1002/cbic.201200413⟩
Thermostable bacterial polymerases like Taq, Therminator and Vent exo(-) are able to perform DNA synthesis by using modified DNA precursors, a property that is exploited in several therapeutic and biotechnological applications. Viral polymerases are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa12d36f442f582c9acaad20494933f
https://hal-pasteur.archives-ouvertes.fr/pasteur-02174665
https://hal-pasteur.archives-ouvertes.fr/pasteur-02174665
