Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Rangnath Mishra"'
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Innate lymphoid cells have the capability to communicate with other immune cell types to coordinate the immune system functioning during homeostasis and inflammation. However, these cells behave differently at the functional level, unlike T cells, th
Externí odkaz:
https://doaj.org/article/0a64b0754e9a4921b3babef3e92b256d
Autor:
Yoko Ito, Reem Al Mubarak, Nicole Roberts, Kelly Correll, William Janssen, James Finigan, Rangnath Mishra, Hong Wei Chu
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196256 (2018)
Alveolar epithelial cells are critical to the pathogenesis of pulmonary inflammation and fibrosis, which are associated with overexpression of type 2 cytokine IL-13. IL-13 is known to induce the production of profibrotic (e.g., periostin) and pro-inf
Externí odkaz:
https://doaj.org/article/80ab5ac4114c49a39ddf3b98a6498f42
Publikováno v:
Current Stem Cell Research & Therapy. 18
Abstract: Diabetes mellitus (DM) is a multifaceted pathological condition, which at present is being considered an epidemic disease keeping the rampant rate of its increase in almost all population groups of the world in consideration. Out of the two
Publikováno v:
Current Pharmaceutical Design. 26:4815-4821
Background: Normal skin pigmentation pattern is an extremely important component of the appearance of a person, as it can be a significant factor in the social context of any person. A condition known as vitiligo is caused by the death of melanocytes
Publikováno v:
Stem cells international. 2022
Innate lymphoid cells have the capability to communicate with other immune cell types to coordinate the immune system functioning during homeostasis and inflammation. However, these cells behave differently at the functional level, unlike T cells, th
Publikováno v:
Biochem Biophys Res Commun
A clear understanding of the mechanisms that regulate the alveolar epithelium's barrier is critical to develop new therapeutic strategies to mitigate lung injury. The HER2/HER3 receptor tyrosine kinase complex plays a central role in maintaining the
Autor:
James H. Finigan, Afshin Dowlati, Eric E. Gardner, Charles M. Rudin, Christopher J. Rivard, Rangnath Mishra, Hui Yu, John T. Poirier, Jihye Kim, Daniel G. Foster, Jeffrey A. Kern, Aik Choon Tan
Publikováno v:
J Thorac Oncol
SCLC represents 15% of all lung cancer diagnoses in the United States and has a particularly poor prognosis. We hypothesized that kinases regulating SCLC survival pathways represent therapeutically targetable vulnerabilities whose inhibition may impr
Autor:
Robert W. Mason, Vihas T. Vasu, Beata Kosmider, Moumita Ghosh, Rangnath Mishra, Jay Finigan, Sonia M. Leach, Jeffrey A. Kern, Daniel G. Foster, Eveline Farias Hesson
Publikováno v:
Am J Respir Cell Mol Biol
The discovery of mutant tyrosine kinases as oncogenic drivers of lung adenocarcinomas has changed the basic understanding of lung cancer development and therapy. Yet, expressed kinases (kinome) in lung cancer progenitor cells, as well as whether kina
Autor:
Hiteshree P, Neel Khokhani, Rangnath Mishra, Anjum Mahmood, Divyang Patel, Shivangi Srivastava, Anjani Srivastava
Publikováno v:
Journal of Stem Cell Research & Therapeutics. 2
Immunotherapies hold the potential for cancer treatment since their mode of action is distinct to chemo and radiation therapy and largely depends on harnessing body rsquo s own immune system The major advantage associated with cancer immunotherapy is
Autor:
Sonia M. Leach, Robert J. Mason, Jeffrey A. Kern, Eveline Farias-Hesson, Vihas T. Vasu, Jihye Kim, Jaewoo Kang, Rangnath Mishra, James H. Finigan, Lynn E. Heasley, Preveen Ramamoorthy, Aik Choon Tan, Minjae Yoo, Katherine R. Singleton
Publikováno v:
Bioinformatics. 30:2393-2398
Motivation: Non–small-cell lung cancer (NSCLC) is the leading cause of cancer death in the United States. Targeted tyrosine kinase inhibitors (TKIs) directed against the epidermal growth factor receptor (EGFR) have been widely and successfully used