Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rangeetha J. Naik"'
Autor:
Jessica F. Almine, Craig A. J. O’Hare, Gillian Dunphy, Ismar R. Haga, Rangeetha J. Naik, Abdelmadjid Atrih, Dympna J. Connolly, Jordan Taylor, Ian R. Kelsall, Andrew G. Bowie, Philippa M. Beard, Leonie Unterholzner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The role of IFI16 as a DNA sensor is highly controversial. With support from aNature Communications back-to-back publication from Jønsson et al., the authors here provide functional evidence that IFI16 is involved in DNA sensing via the cGAS-STING p
Externí odkaz:
https://doaj.org/article/eb5ed45912da4959a911474e177edfb0
Autor:
Moneesha Fernandes, Amit K. Yadav, Manika Vij, Kiran M. Patil, Munia Ganguli, Rangeetha J. Naik, Vaijayanti A. Kumar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:4198-4202
The syntheses of novel N -aminoalkyl proline-derived spacers (X′) in polycationic (R–X′–R)-motif cell-penetrating α–ω–α-peptides are described as improved molecular transporters and their structural features studied by CD. FACS analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed14812a7165e4fd57c3b52bb30f4e4
https://doi.org/10.1016/j.bmcl.2014.07.040
https://doi.org/10.1016/j.bmcl.2014.07.040
Autor:
Munia Ganguli, Vaijayanti A. Kumar, Moneesha Fernandes, Rangeetha J. Naik, Kiran M. Patil, Rajpal
Publikováno v:
Journal of the American Chemical Society. 134:7196-7199
The (R-X-R) motif-containing arginine-rich peptides are among the most effective cell-penetrating peptides. The replacement of amide linkages in the (R-X-R) motif by carbamate linkages as in (r-ahx-r)(4) or (r-ahx-r-r-apr-r)(2) increases the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd311dd2b1f11fd206147f27cf9b99e9
https://doi.org/10.1021/ja210026m
https://doi.org/10.1021/ja210026m
Publikováno v:
Biochimica et biophysica acta. 1848(4)
Arginine-rich peptides have been used extensively as efficient cellular transporters. However, gene delivery with such peptides requires development of strategies to improve their efficiency. We had earlier demonstrated that addition of small amounts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfbdbf7425c9e744b66760980377bfc
https://pubmed.ncbi.nlm.nih.gov/25637297
https://pubmed.ncbi.nlm.nih.gov/25637297
Publikováno v:
Drug discovery today. 14(5-6)
For more than two decades, gene therapy has sought to treat diseases with a genetic component. The eye is a promising target organ for gene therapy because of its unique features like easy accessibility and convenient methods of direct assessment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3aadf697ae12869223f9d81fb7ee88f
https://pubmed.ncbi.nlm.nih.gov/18973824
https://pubmed.ncbi.nlm.nih.gov/18973824
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (6):1484-1493
The role of cell surface and exogenous glycosaminoglycans (GAGs) in DNA delivery by cationic peptides is controlled to a large extent by the peptide chemistry and the nature of its complex with DNA. We have previously shown that complexes formed by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53db5de1a7ed3e6da82d82ba0502c39f