Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Rangarajan, D"'
Autor:
Jeffrey D. Steimle, Chul Kim, Megan Rowton, Rangarajan D. Nadadur, Zhezhen Wang, Matthew Stocker, Andrew D. Hoffmann, Erika Hanson, Junghun Kweon, Tanvi Sinha, Kyunghee Choi, Brian L. Black, John M. Cunningham, Ivan P. Moskowitz, Kohta Ikegami
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112665- (2023)
Summary: Mechanisms underlying distinct specification, commitment, and differentiation phases of cell fate determination remain undefined due to difficulties capturing these processes. Here, we interrogate the activity of ETV2, a transcription factor
Externí odkaz:
https://doaj.org/article/a4f6e11b99da453fa7f6cb62c465d663
Publikováno v:
In Journal of Computational Physics 1 September 2022 464
Akademický článek
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Autor:
Steimle, Jeffrey D., Rankin, Scott A., Slagle, Christopher E., Bekeny, Jenna, Rydeen, Ariel B., Chan, Sunny Sun-Kin, Kweon, Junghun, Yang, Xinan H., Ikegami, Kohta, Nadadur, Rangarajan D., Rowton, Megan, Hoffmann, Andrew D., Lazarevic, Sonja, Thomas, William, Anderson, Erin A. T. Boyle, Horb, Marko E., Luna-Zurita, Luis, Ho, Robert K., Kyba, Michael, Jensen, Bjarke, Zorn, Aaron M., Conlon, Frank L., Moskowitz, Ivan P.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Nov 01. 115(45), E10615-E10624.
Externí odkaz:
https://www.jstor.org/stable/26563210
Autor:
Catherine E. Lipovsky, Jesus Jimenez, Qiusha Guo, Gang Li, Tiankai Yin, Stephanie C. Hicks, Somya Bhatnagar, Kentaro Takahashi, David M. Zhang, Brittany D. Brumback, Uri Goldsztejn, Rangarajan D. Nadadur, Carlos Perez-Cervantez, Ivan P. Moskowitz, Shaopeng Liu, Bo Zhang, Stacey L. Rentschler
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Atrial fibrillation (AF) is the most common cardiac arrhythmia, yet the molecular signature of the vulnerable atrial substrate is not well understood. Here, we delineated a distinct transcriptional signature in right versus left atrial cardiomyocytes
Externí odkaz:
https://doaj.org/article/47324dd7c833416f9a9884ad95536924
Autor:
Andrea Iorga, Soban Umar, Gregoire Ruffenach, Laila Aryan, Jingyuan Li, Salil Sharma, Negar Motayagheni, Rangarajan D. Nadadur, Jean C. Bopassa, Mansoureh Eghbali
Publikováno v:
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-11 (2018)
Abstract Background Recently, we showed that exogenous treatment with estrogen (E2) rescues pre-existing advanced heart failure (HF) in mice. Since most of the biological actions of E2 are mediated through the classical estrogen receptors alpha (ERα
Externí odkaz:
https://doaj.org/article/22e35acfd0794347847aa8595074ace5
Akademický článek
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Publikováno v:
International Journal of Research and Review. 9:398-402
Aims and objectives: To estimate the proportion of Hyperuricemia in patients with type 2 Diabetes Mellitus and Hypertension patients and to assess the correlation of serum uric acid and urine uric acid. To assess the relationship between Urine Uric a
Autor:
Wenli Dai, Brigitte Laforest, Leonid Tyan, Kaitlyn M Shen, Rangarajan D Nadadur, Francisco J Alvarado, Stefan R Mazurek, Sonja Lazarevic, Margaret Gadek, Yitang Wang, Ye Li, Hector H Valdivia, Le Shen, Michael T Broman, Ivan P Moskowitz, Christopher R Weber
Publikováno v:
eLife, Vol 8 (2019)
Risk for Atrial Fibrillation (AF), the most common human arrhythmia, has a major genetic component. The T-box transcription factor TBX5 influences human AF risk, and adult-specific Tbx5-mutant mice demonstrate spontaneous AF. We report that TBX5 is c
Externí odkaz:
https://doaj.org/article/5542066897174d2fb4a630960edaea63
Autor:
Xinan H Yang, Rangarajan D Nadadur, Catharina RE Hilvering, Valerio Bianchi, Michael Werner, Stefan R Mazurek, Margaret Gadek, Kaitlyn M Shen, Joseph Aaron Goldman, Leonid Tyan, Jenna Bekeny, Johnathon M Hall, Nutishia Lee, Carlos Perez-Cervantes, Ozanna Burnicka-Turek, Kenneth D Poss, Christopher R Weber, Wouter de Laat, Alexander J Ruthenburg, Ivan P Moskowitz
Publikováno v:
eLife, Vol 6 (2017)
The noncoding genome is pervasively transcribed. Noncoding RNAs (ncRNAs) generated from enhancers have been proposed as a general facet of enhancer function and some have been shown to be required for enhancer activity. Here we examine the transcript
Externí odkaz:
https://doaj.org/article/483cf25f032e4eb3bd37b9b1b0cee643