Heterotypic interactions can drive selective co-condensation of prion-like low-complexity domains of FET proteins and mammalian SWI/SNF complex.

Autor: Davis RB; Department of Physics, University at Buffalo, Buffalo, NY, 14260, USA., Supakar A; Department of Biological Sciences, University at Buffalo, Buffalo, NY, 14260, USA., Ranganath AK; Department of Chemical and Biological Engineering, University at Buffalo, Buffalo, NY, 14260, USA., Moosa MM; Department of Physics, University at Buffalo, Buffalo, NY, 14260, USA., Banerjee PR; Department of Physics, University at Buffalo, Buffalo, NY, 14260, USA. prbanerj@buffalo.edu.; Department of Biological Sciences, University at Buffalo, Buffalo, NY, 14260, USA. prbanerj@buffalo.edu.; Department of Chemical and Biological Engineering, University at Buffalo, Buffalo, NY, 14260, USA. prbanerj@buffalo.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Feb 07; Vol. 15 (1), pp. 1168. Date of Electronic Publication: 2024 Feb 07.

Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior.

Autor: Schuster BS; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.; Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, NJ 08854., Dignon GL; Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA 18015.; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY 11794., Tang WS; Department of Physics, Brown University, Providence, RI 02912., Kelley FM; Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, NJ 08854., Ranganath AK; Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, NJ 08854., Jahnke CN; Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA 19104., Simpkins AG; Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA 19104., Regy RM; Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA 18015., Hammer DA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.; Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA 19104., Good MC; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104., Mittal J; Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA 18015; jeetain@lehigh.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 May 26; Vol. 117 (21), pp. 11421-11431. Date of Electronic Publication: 2020 May 11.