Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Ranganath, Muniyappa"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
We address a problem with the Bergman-Cobelli Minimal Model, which has been used for 40 years to estimate SI during an intravenous glucose tolerance test (IVGTT). During the IVGTT blood glucose and insulin concentrations are measured in response to a
Externí odkaz:
https://doaj.org/article/1202fc6ac37b4639a0fab231f2da749f
Autor:
Marissa Lightbourne, Megan Startzell, Kimberley D. Bruce, Brianna Brite, Ranganath Muniyappa, Monica Skarulis, Robert Shamburek, Ahmed M. Gharib, Ronald Ouwerkerk, Mary Walter, Robert H. Eckel, Rebecca J. Brown
Publikováno v:
Journal of Clinical Lipidology. 16:850-862
Partial lipodystrophy (PL) syndromes involve deficiency of adipose tissue, causing severe insulin resistance and hypertriglyceridemia. Apolipoprotein C-III (apoC-III) is elevated in PL and is thought to contribute to hypertriglyceridemia by inhibitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f7fc729587191e7377087d23c5b6f3
https://doi.org/10.1016/j.jacl.2022.06.011
https://doi.org/10.1016/j.jacl.2022.06.011
Autor:
Mary T Korytkowski, Ranganath Muniyappa, Kellie Antinori-Lent, Amy C Donihi, Andjela T Drincic, Irl B Hirsch, Anton Luger, Marie E McDonnell, M Hassan Murad, Craig Nielsen, Claire Pegg, Robert J Rushakoff, Nancy Santesso, Guillermo E Umpierrez
Publikováno v:
J Clin Endocrinol Metab
BackgroundAdult patients with diabetes or newly recognized hyperglycemia account for over 30% of noncritically ill hospitalized patients. These patients are at increased risk for adverse clinical outcomes in the absence of defined approaches to glyce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2412f1c870706e9c06769cb91de4c1f3
https://doi.org/10.1210/clinem/dgac278
https://doi.org/10.1210/clinem/dgac278
Autor:
Christopher R McCartney, Maureen D Corrigan, Matthew T Drake, Ghada El-Hajj Fuleihan, Mary T Korytkowski, Robert W Lash, David C Lieb, Anthony L McCall, Ranganath Muniyappa, Thomas Piggott, Nancy Santesso, Holger J Schünemann, Wojtek Wiercioch, Marie E McDonnell, M Hassan Murad
Publikováno v:
J Clin Endocrinol Metab
In an effort to enhance the trustworthiness of its clinical practice guidelines, the Endocrine Society has recently adopted new policies and more rigorous methodologies for its guideline program. In this Clinical Practice Guideline Communication, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2f5d2fb5caf8897f14ac88bc24fe27
https://doi.org/10.1210/clinem/dgac290
https://doi.org/10.1210/clinem/dgac290
Autor:
Ranganath Muniyappa, Rasimcan Meral, Noemi Malandrino, Elif A. Oral, Rebecca J. Brown, Mary Walter, Adam H. Neidert
Publikováno v:
J Clin Endocrinol Metab
Context Leptin replacement with metreleptin improves glycemia and hypertriglyceridemia in severely hypoleptinemic patients with generalized lipodystrophy (GLD), but its effects are variable in partially leptin-deficient patients with partial lipodyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fda882f4d71d61ea7f18f3f3666cdf
https://doi.org/10.1210/clinem/dgab760
https://doi.org/10.1210/clinem/dgab760
Autor:
Andin Fosam, Rashika Bansal, Amrita Ramanathan, Camila Sarcone, Indiresha Iyer, Meena Murthy, Alan T Remaley, Ranganath Muniyappa
Publikováno v:
J Endocr Soc
Context Identification of insulin resistance (IR) in South Asians, who are at a higher risk for type 2 diabetes, is important. Lack of standardization of insulin assays limits the clinical use of insulin-based surrogate indices. The lipoprotein insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce29317a390b24141786cc825b3aa873
https://europepmc.org/articles/PMC9830979/
https://europepmc.org/articles/PMC9830979/
Autor:
Ranganath Muniyappa, Shannon D. Sullivan, Sri Harsha Tella, Brent S. Abel, S. Mitchell Harman, Marc R. Blackman
Publikováno v:
Physiological Reports, Vol 5, Iss 23, Pp n/a-n/a (2017)
Abstract The known interactions between the somatotropic and hypothalamic‐pituitary‐gonadal (HPG) axes have not been well delineated in older individuals. Aging‐associated decline in insulin like growth factor‐1 (IGF‐1) levels has been prop
Externí odkaz:
https://doaj.org/article/d821165fa76444eaa335e4260539933d
Autor:
Ranganath Muniyappa, Shivraj Grewal, Andin Fosam, Susan Yuditskaya, Camila Sarcone, Hubert Fan
Publikováno v:
Diabetes Care
OBJECTIVE To examine the ethnic differences in insulin sensitivity (SI) as measured by the minimal model approach (SI-MM) and the reference method, the euglycemic-hyperinsulinemic clamp (EHC). RESEARCH DESIGN AND METHODS In a prospective study design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854d6fb4210c4a48ff793607834387f9
https://doi.org/10.2337/dc21-0490
https://doi.org/10.2337/dc21-0490
Autor:
Shivraj Grewal, Sriram Gubbi, Ranganath Muniyappa, Raven McGlotten, Lynnette K. Nieman, Susmeeta T. Sharma
Publikováno v:
J Clin Endocrinol Metab
Background Increased tissue cortisol availability has been implicated in abnormal glucose and fat metabolism in patients with obesity, metabolic syndrome, and type 2 diabetes (T2DM). Our objective was to evaluate whether blockade of glucocorticoid re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c72cacd5ef02db56a47c7f047c7ec06
https://doi.org/10.1210/clinem/dgab046
https://doi.org/10.1210/clinem/dgab046
Publikováno v:
Am J Physiol Endocrinol Metab
Previously, we have used mathematical modeling to gain mechanistic insights into insulin-stimulated glucose uptake. Phosphatidylinositol 3-kinase (PI3K)-dependent insulin signaling required for metabolic actions of insulin also regulates endothelium-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107c3d12371135575c2b5d91bf1753a5
https://doi.org/10.1152/ajpendo.00247.2020
https://doi.org/10.1152/ajpendo.00247.2020