Shift of microRNA profile upon orthotopic xenografting of glioblastoma spheroid cultures

Autor: Morten Meyer, Mia D. Sørensen, Eric G. Marcusson, Stine Skov Jensen, Sune Munthe, Mette Katrine Schulz, Torben A Kruse, Jan Mollenhauer, Bo Halle, Mads Thomassen, Ranga Venkatesan, Bjarne Winther Kristensen, Vivek Kaimal, Steffen J. Schmidt, Helle Christiansen, Charlotte Aaberg-Jessen, Claus Andersen

Publikováno v: Halle, B, Thomassen, M, Venkatesan, R, Kaimal, V, Marcusson, E G, Munthe, S, Sørensen, M D, Aaberg-Jessen, C, Jensen, S S, Meyer, M, Kruse, T A, Christiansen, H, Schmidt, S, Mollenhauer, J, Schulz, M K, Andersen, C & Kristensen, B W 2016, ' Shift of microRNA profile upon orthotopic xenografting of glioblastoma spheroid cultures ', Journal of Neuro-Oncology, vol. 128, no. 3, pp. 395–404 . https://doi.org/10.1007/s11060-016-2125-x

Glioblastomas always recur despite surgery, radiotherapy and chemotherapy. A key player in the therapeutic resistance may be immature tumor cells with stem-like properties (TSCs) escaping conventional treatment. A group of promising molecular targets

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e50aba8cfa9c60411b10566ae407fd
https://doi.org/10.1007/s11060-016-2125-x