Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ranga N Parthasarathy"'
Autor:
Janani Ramesh, Latha K Parthasarathy, Anthony J Janckila, Farhana Begum, Ramya Murugan, Balakumar P S S Murthy, Rif S El-Mallakh, Ranga N Parthasarathy, Bhuvarahamurthy Venugopal
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230052 (2020)
Biallelic mutations in ACP5, encoding tartrate-resistant acid phosphatase (TRACP), have recently been identified to cause the inherited immuno-osseous disorder, spondyloenchondrodysplasia (SPENCD). This study was undertaken to characterize the eight
Externí odkaz:
https://doaj.org/article/a68b625c6a104f0aad25ad980565ae25
Autor:
Balakumar P. S. S. Murthy, Anthony J. Janckila, Janani Ramesh, Bhuvarahamurthy Venugopal, Ranga N. Parthasarathy, Latha K. Parthasarathy, Farhana Begum, Rif S. El-Mallakh, Ramya Murugan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0230052 (2020)
PLoS ONE, Vol 15, Iss 3, p e0230052 (2020)
Biallelic mutations in ACP5, encoding tartrate-resistant acid phosphatase (TRACP), have recently been identified to cause the inherited immuno-osseous disorder, spondyloenchondrodysplasia (SPENCD). This study was undertaken to characterize the eight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42767d9653acebfdc8d01d4c0797a3b2
http://europepmc.org/articles/PMC7098635
http://europepmc.org/articles/PMC7098635
Autor:
Rifaat Shody El-Mallakh, Ratnam S. Seelan, John I. Stagner, Muthusamy Thangavel, Jaganathan Lakshmanan, Robert Vadnal, Manuel F. Casanova, Ranga N. Parthasarathy, Latha K. Parthasarathy
Publikováno v:
Journal of Neuroscience Research. 92:927-936
Valproic acid (VPA) is commonly used to treat bipolar disorder (BD), but its therapeutic role has not been clearly elucidated. To gain insights into VPA's mechanism of action, proteomic analysis was used to identify differentially expressed proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76fd69d0849e63a7122ec3534af7e5e1
https://doi.org/10.1002/jnr.23373
https://doi.org/10.1002/jnr.23373
Autor:
Anthony J. Janckila, Ranga N. Parthasarathy, Yi-Ying Wu, Stephen P. Slone, Lung T. Yam, Tsu Yi Chao, Silvia D Potenziani Pradella
Publikováno v:
Journal of Immunological Methods. 372:162-170
Background Tartrate-resistant acid phosphatase (TRACP) is an enzyme common to cells of the mononuclear phagocyte system and a clinically relevant biomarker for osteoclasts and inflammatory macrophages. The purpose was to assess applications and perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a290bdfecdc4eb082e30f44c62b3fc
https://doi.org/10.1016/j.jim.2011.07.010
https://doi.org/10.1016/j.jim.2011.07.010
Autor:
Manuel F. Casanova, Robert M. Greene, M. Michele Pisano, Ratnam S. Seelan, Ranga N. Parthasarathy
Publikováno v:
Epigenomics. 3:111-124
Aims: Myo-inositol levels are frequently altered in several brain disorders. Myo-inositol 3-phosphate synthase, encoded by the Isyna1 gene, catalyzes the synthesis of myo-inositol in cells. Very little is known about the mechanisms regulating Isyna1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b535aff9ae643857c75984379876d5
https://doi.org/10.2217/epi.10.73
https://doi.org/10.2217/epi.10.73
Publikováno v:
Journal of Biological Chemistry. 284:9443-9457
myo-Inositol is an important constituent of membrane phospholipids and is a precursor for the phosphoinositide signaling pathway. It is synthesized from glucose 6-phosphate by myo-inositol-3-phosphate synthase (IP synthase), a homotrimer composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::355c1711eab01bb69ae88647d7145531
https://doi.org/10.1074/jbc.m900206200
https://doi.org/10.1074/jbc.m900206200
Autor:
Abdelnaby Khalyfa, Manuel F. Casanova, J. Lakshmanan, Ranga N. Parthasarathy, Ratnam S. Seelan
Publikováno v:
Neuroscience. 151:1184-1197
The mechanisms underlying lithium's therapeutic efficacy in the chronic treatment of bipolar disorder are not clearly understood. Useful insights can be obtained by identifying genes that are differentially regulated during chronic lithium treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5cda0d769bd3dcff8969e9dbe132ee
https://doi.org/10.1016/j.neuroscience.2007.10.045
https://doi.org/10.1016/j.neuroscience.2007.10.045
Autor:
Tiina Laitala-Leinonen, Tuula Tennilä, Ranga N. Parthasarathy, Elena Azhayeva, Anthony J. Janckila, Pirkko Muhonen, H. Kalervo Väänänen, Alex Azhayev
Publikováno v:
Chemistry & Biodiversity. 4:858-873
Short interfering RNA (siRNA) molecules with good gene-silencing properties are needed for drug development based on RNA interference (RNAi). An initial step in RNAi is the activation of the RNA-induced silencing complex RISC, which requires degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be618df8b8cea22b21c46c61c7c199ec
https://doi.org/10.1002/cbdv.200790073
https://doi.org/10.1002/cbdv.200790073
Autor:
Ratnam S. Seelan, Jukka P. Rissanen, Yi-Cheung Hsueh, Jussi M. Halleen, Anthony J. Janckila, Latha K. Parthasarathy, Lung T. Yam, Sari L. Alatalo, Ranga N. Parthasarathy
Publikováno v:
Journal of Leukocyte Biology. 77:209-218
Human serum tartrate-resistant acid phosphatase exists as two enzyme isoforms (TRACP 5a and 5b), derived by differential, post-translational processing of a common gene product. Serum TRACP 5b is from bone-resorbing osteoclasts (OC) and becomes eleva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af0ad60398bc89650d726a82b99fb4b
https://doi.org/10.1189/jlb.0504287
https://doi.org/10.1189/jlb.0504287
Publikováno v:
Archives of Biochemistry and Biophysics. 431:95-106
Human myo -inositol 1-phosphate synthase (IP synthase; E.C. 5.5.1.4), encoded by ISYNA1 , catalyzes the de novo synthesis of inositol 1-phosphate from glucose 6-phosphate. It is a potential target for mood-stabilizing drugs such as lithium and valpro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d608b53dfa911ef25c964c637f6fa46
https://doi.org/10.1016/j.abb.2004.08.002
https://doi.org/10.1016/j.abb.2004.08.002