Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Rang Woon Park"'
Multifunctional elastin-like polypeptide nanocarriers for efficient miRNA delivery in cancer therapy
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background The exogenous delivery of miRNA to mimic and restore miRNA-34a activity in various cancer models holds significant promise in cancer treatment. Nevertheless, its effectiveness is often impeded by challenges, including a short half
Externí odkaz:
https://doaj.org/article/d8f88be1330842fbaaca5ff448507bb2
Autor:
Jaebeom Cho, Hye-Young Min, Ho Jin Lee, Seung Yeob Hyun, Jeong Yeon Sim, Myungkyung Noh, Su Jung Hwang, Shin-Hyung Park, Hye-Jin Boo, Hyo-Jong Lee, Sungyoul Hong, Rang-Woon Park, Young Kee Shin, Mien-Chie Hung, Ho-Young Lee
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/b6b023cda3b74a22bcca808bf29b5323
Autor:
Hye‐Young Min, Jaebeom Cho, Jeong Yeon Sim, Hye‐Jin Boo, Ji‐Sun Lee, Seon‐Boon Lee, Young‐Jin Lee, Sung Joo Kim, Kyu‐Pyo Kim, In‐Ja Park, Seung‐Mo Hong, Xue‐Li Zhang, Zhi‐Gang Zhang, Rang‐Woon Park, Ho‐Young Lee
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background Programmed death‐ligand 1 (PD‐L1) has functional roles in cancer stem‐like cell (CSC) phenotypes and chemoresistance besides immune evasion. Chemotherapy is a common treatment choice for colorectal cancer (CRC) patients; how
Externí odkaz:
https://doaj.org/article/7c30c7044e43480a9579cda7dfd51674
Publikováno v:
Biomaterials and Biosystems, Vol 6, Iss , Pp 100050- (2022)
Successful gene delivery depends on the entry of negatively charged DNAs and oligonucleotides across the various barriers of the tumor cells and localization into the nucleus for its transcription and protein translation. Here, we have reported a the
Externí odkaz:
https://doaj.org/article/876c039849de46c5aa8f0c90c9c3c127
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appears as most efficient a
Externí odkaz:
https://doaj.org/article/177d5d071832423dbaf4264fde0e3407
Autor:
Hye-Jin Boo, Hye-Young Min, Choon-Sik Park, Jong-Sook Park, Ji Yun Jeong, Shin Yup Lee, Woo-Young Kim, Jae-Won Lee, Sei-Ryang Oh, Rang-Woon Park, Ho-Young Lee
Publikováno v:
Cancer Research. :OF1-OF18
Pulmonary emphysema is a destructive inflammatory disease primarily caused by cigarette smoking (CS). Recovery from CS-induced injury requires proper stem cell (SC) activities with a tightly controlled balance of proliferation and differentiation. He
Autor:
Vijaya Sarangthem, Harshita Sharma, Mohini Mendiratta, Ranjit Kumar Sahoo, Rang-Woon Park, Lalit Kumar, Thoudam Debraj Singh, Sujata Mohanty
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1151 (2022)
Regenerative medicine using stem cells offers promising strategies for treating a variety of degenerative diseases. Regulation of stem cell behavior and rejuvenate senescence are required for stem cells to be clinically effective. The extracellular m
Externí odkaz:
https://doaj.org/article/2e7aae115e2848188b76b08f8156bec9
Autor:
Ho-Young Lee, Rang-Woon Park, Sei-Ryang Oh, Jae-Won Lee, Woo-Young Kim, Shin Yup Lee, Ji Yun Jeong, Jong-Sook Park, Choon-Sik Park, Hye-Young Min, Hye-Jin Boo
Supplementary Methods, Tables, and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2c714c4b2d2583b717d6c1224b8b75
https://doi.org/10.1158/0008-5472.22929944
https://doi.org/10.1158/0008-5472.22929944
Autor:
Ho-Young Lee, Rang-Woon Park, Sei-Ryang Oh, Jae-Won Lee, Woo-Young Kim, Shin Yup Lee, Ji Yun Jeong, Jong-Sook Park, Choon-Sik Park, Hye-Young Min, Hye-Jin Boo
Pulmonary emphysema is a destructive inflammatory disease primarily caused by cigarette smoking (CS). Recovery from CS-induced injury requires proper stem cell (SC) activities with a tightly controlled balance of proliferation and differentiation. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075456cf85c9a66e40f9e894b93dcc04
https://doi.org/10.1158/0008-5472.c.6653426.v1
https://doi.org/10.1158/0008-5472.c.6653426.v1
Autor:
Su Jung Hwang, Hye-Young Min, Rang Woon Park, Jaebeom Cho, Ho-Young Lee, Mien Chie Hung, Hyo Jong Lee, Ho Jin Lee, Jeong Yeon Sim, Myungkyung Noh, Shin-Hyung Park, Seung Yeob Hyun, Hye-Jin Boo, Sungyoul Hong, Young Kee Shin
Publikováno v:
J Clin Invest
Slow-cycling/dormant cancer cells (SCCs) have pivotal roles in driving cancer relapse and drug resistance. A mechanistic explanation for cancer cell dormancy and therapeutic strategies targeting SCCs are necessary to improve patient prognosis, but ar