Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Raneen Rahhal"'
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2851-2865.e3 (2018)
Summary: The protein deacetylase SIRT1 (Sirtuin 1) regulates many cellular processes, including cell-cycle progression, DNA damage response, and metabolism. Although the centrosome is a key regulator of cell-cycle progression and genome stability, li
Externí odkaz:
https://doaj.org/article/0245e75d417345d48993aae2d8ff7d8e
Autor:
Giuseppe Giaccone, Udayan Guha, Yu-Wen Zhang, Yisong Wang, Anna T. Alberobello, Raneen Rahhal, Justine N. McCutcheon, Jose Antonio Rodriguez, Yoko Yonemori, Tommaso De Pas, Guanhua Rao, Xu Zhang, Fabio Conforti
Affected pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27290e341242a2fa157fc78be77fa645
https://doi.org/10.1158/0008-5472.22414037
https://doi.org/10.1158/0008-5472.22414037
Autor:
Giuseppe Giaccone, Udayan Guha, Yu-Wen Zhang, Yisong Wang, Anna T. Alberobello, Raneen Rahhal, Justine N. McCutcheon, Jose Antonio Rodriguez, Yoko Yonemori, Tommaso De Pas, Guanhua Rao, Xu Zhang, Fabio Conforti
Exportin 1 (XPO1) mediates nuclear export of many cellular factors known to play critical roles in malignant processes, and selinexor (KPT-330) is the first XPO1-selective inhibitor of nuclear export compound in advanced clinical development phase fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207e2fbbfddd5ec463c3021b691f96ad
https://doi.org/10.1158/0008-5472.c.6508871
https://doi.org/10.1158/0008-5472.c.6508871
Autor:
Giuseppe Giaccone, Udayan Guha, Yu-Wen Zhang, Yisong Wang, Anna T. Alberobello, Raneen Rahhal, Justine N. McCutcheon, Jose Antonio Rodriguez, Yoko Yonemori, Tommaso De Pas, Guanhua Rao, Xu Zhang, Fabio Conforti
Effects of XPO1 knockdown on NF-κB and cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516e25ad386f9dcdacdc2412f155a045
https://doi.org/10.1158/0008-5472.22414055
https://doi.org/10.1158/0008-5472.22414055
Autor:
Gray W. Pearson, Rolf A. Brekken, Anna T. Riegel, Tuyen T. Dang, Raneen Rahhal, Molly E. Huysman, Apsra Nasir, Sharon Camacho, Jill M. Westcott
Live imaging of explants containing MCFDCISO cells (H2B:mCherry, red, nuclei) with or without 578T cells (H2B:GFP, green, nuclei) showing cell motility.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29feb68f8f44bf4d2ac4f08dae2f5322
https://doi.org/10.1158/0008-5472.22426362.v1
https://doi.org/10.1158/0008-5472.22426362.v1
Autor:
Gray W. Pearson, Rolf A. Brekken, Anna T. Riegel, Tuyen T. Dang, Raneen Rahhal, Molly E. Huysman, Apsra Nasir, Sharon Camacho, Jill M. Westcott
Defining how interactions between tumor subpopulations contribute to invasion is essential for understanding how tumors metastasize. Here, we find that the heterogeneous expression of the transcription factor ΔNp63 confers distinct proliferative and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e8684518175a50c92c429f17cec3fc
https://doi.org/10.1158/0008-5472.c.6512316.v1
https://doi.org/10.1158/0008-5472.c.6512316.v1
Autor:
Gray W. Pearson, Rolf A. Brekken, Anna T. Riegel, Tuyen T. Dang, Raneen Rahhal, Molly E. Huysman, Apsra Nasir, Sharon Camacho, Jill M. Westcott
Supplemental Figures S1-S5 and Supplemental Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de6f84a5b7e78996b6725b376f14b9e
https://doi.org/10.1158/0008-5472.22426383
https://doi.org/10.1158/0008-5472.22426383
Autor:
Gregory T. Gallanis, Ghada M. Sharif, Marcel O. Schmidt, Benjamin N. Friedland, Rohith Battina, Raneen Rahhal, John E. Davis, Irfan S. Khan, Anton Wellstein, Anna T. Riegel
Publikováno v:
Cancers; Volume 15; Issue 6; Pages: 1908
Background: CDK4/6 inhibitors (CDKi) have improved disease control in hormone-receptor-positive, HER2-negative metastatic breast cancer, but most patients develop progressive disease. Methods: We asked whether host stromal senescence after CDK4/6 inh
Autor:
Jill M. Westcott, Raneen Rahhal, Anna T. Riegel, Sharon Camacho, Rolf A. Brekken, Gray W. Pearson, Molly E. Huysman, Tuyen T. Dang, Apsra Nasir
Publikováno v:
Cancer Res
Defining how interactions between tumor subpopulations contribute to invasion is essential for understanding how tumors metastasize. Here, we find that the heterogeneous expression of the transcription factor ΔNp63 confers distinct proliferative and
Autor:
Raneen Rahhal, Edward Seto
Publikováno v:
Nucleic Acids Research
Histone modifications and RNA splicing, two seemingly unrelated gene regulatory processes, greatly increase proteome diversity and profoundly influence normal as well as pathological eukaryotic cellular functions. Like many histone modifying enzymes,