Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Randy W. Cohen"'
Autor:
Wesley M. Tierney, Toni L. Uhlendorf, Aaron J.J. Lemus, Bianca A. Ortega, Jesse Magaña, Jessica Ochoa, William Van Trigt, Angelica Cruz, Alex Kopyov, Oleg V. Kopyov, Randy W. Cohen
Publikováno v:
Cell Transplantation, Vol 29 (2020)
The spastic Han Wistar (sHW) rat serves as a model for human ataxia presenting symptoms of motor deterioration, weight loss, shortened lifespan, and Purkinje neuron loss. Past studies revealed that human neural progenitor cells (NPCs) improved ataxic
Externí odkaz:
https://doaj.org/article/f98e01d0561b4ba7be40a22ae64194ad
Autor:
Ruslan L. Nuryyev, Toni L. Uhlendorf, Wesley Tierney, Suren Zatikyan, Oleg Kopyov, Alex Kopyov, Jessica Ochoa, William Van Trigt, Cindy S. Malone, Randy W. Cohen
Publikováno v:
Cell Transplantation, Vol 26 (2017)
The use of regenerative medicine to treat nervous system disorders like ataxia has been proposed to either replace or support degenerating neurons. In this study, we assessed the ability of human neural progenitor cells (hNPCs) to repair and restore
Externí odkaz:
https://doaj.org/article/3d78eecc73714e53b5092f2b2a69e96a
Autor:
Toni L. Uhlendorf, Ruslan L. Nuryyev, Alex O. Kopyov, Jessica Ochoa, Shahab Younesi, Randy W. Cohen, Oleg V. Kopyov
Publikováno v:
Cell Transplantation, Vol 26 (2017)
An emerging avenue for recalcitrant neurodegenerative disease treatment is neural progenitor cell (NPC) transplantation. In this study, we investigated the effectiveness of two different delivery routes of human-derived NPC inoculation: injection int
Externí odkaz:
https://doaj.org/article/e7b0417e0504429a8987b144120e78d4
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 7, Pp 1413-1414 (2021)
Externí odkaz:
https://doaj.org/article/e04a898e34a2477a9e403baa5551e9da
Autor:
Cindy S. Malone, Jacqueline Saenz, William Van Trigt, Ruslan L Nuryyev, Randy W. Cohen, Jessica Ochoa, Menaga Shanmugam, Andrew P St. Julian, Celavie Biosciences Llc, Oxnard, Ca Usa, Toni L. Uhlendorf, Alex Kopyov, Sabrina K Uppal, Oleg V. Kopyov
Publikováno v:
AIMS Medical Science. 8:252-268
It has been established that the CA3 region of the hippocampus is involved in consolidating short-term memory to long-term memory and aids in spatial navigation retention. Seizures and many neurologic diseases induce damage to that region of the hipp
Autor:
Jesse Magaña, Jessica Ochoa, Aaron J J Lemus, Wesley M Tierney, William Van Trigt, Alex Kopyov, Angelica Cruz, Toni L. Uhlendorf, Oleg V. Kopyov, Randy W. Cohen, Bianca A Ortega
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Cell Transplantation
Cell Transplantation
The spastic Han Wistar (sHW) rat serves as a model for human ataxia presenting symptoms of motor deterioration, weight loss, shortened lifespan, and Purkinje neuron loss. Past studies revealed that human neural progenitor cells (NPCs) improved ataxic
Publikováno v:
Biology letters. 14(5)
Vestigial morphological traits are common and well known in a variety of taxa. Identification of vestigial genes has illustrated the potential for evolutionary reversals and the re-expression of atavistic traits. Here we induce expression of a behavi
Autor:
Randy W. Cohen, M. S. Shanmugam, Ricardo Hernandez, Toni L. Uhlendorf, A. Cruz, William M. Tierney
Population studies in the United States indicate that there are over 40 million people over 65 years of age. Age-related cognitive decline and their associated neuronal disorders have been shown to disturb neurological processes such as memory, learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6f3c57ba1bc98bdbc8f2b66628266b
https://doi.org/10.1016/b978-0-12-805094-1.00009-5
https://doi.org/10.1016/b978-0-12-805094-1.00009-5
Publikováno v:
Journal of Experimental Biology. 214:3843-3849
SUMMARYInsects, including cockroaches, self-select a balanced diet when faced with different nutrient choices. For self-selection to be carried out effectively, insects possess neuroregulatory systems to control their food intake. In the present stud
Publikováno v:
Brain Research. 1369:216-222
Research has shown that physical exercise may reduce degeneration in certain brain regions experiencing ataxia. Our laboratory utilized mutant spastic Han–Wistar rats (sHW) that display developmental abnormalities, including spastic paresis, fore l