Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Randy Robinson"'
Autor:
Victor M. Villalobos, Anthony Tolcher, James P. Allison, Padmanee Sharma, Randy Robinson, James W. Purcell, Akshanth R. Polepally, Huibin Yue, Dominic W. Lai, Hua Fang, Chris Chen, Louie Naumovski, Vivek Subbiah, Alexander I. Spira, John D. Powderly, Antoine Hollebecque, Jason J. Luke, George D. Demetri
Supplementary Table S2 shows LRRC15 IHC expression in tumor and stroma of patients with sarcoma treated ABBV-085 monotherapy at 3.6 or 4.2 mg/kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2759a945219be6472c0fcb49ad3fe7
https://doi.org/10.1158/1078-0432.22479056.v1
https://doi.org/10.1158/1078-0432.22479056.v1
Autor:
Victor M. Villalobos, Anthony Tolcher, James P. Allison, Padmanee Sharma, Randy Robinson, James W. Purcell, Akshanth R. Polepally, Huibin Yue, Dominic W. Lai, Hua Fang, Chris Chen, Louie Naumovski, Vivek Subbiah, Alexander I. Spira, John D. Powderly, Antoine Hollebecque, Jason J. Luke, George D. Demetri
Supplementary Figure S1 shows the study design.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f740555983e19b1c823b9f0c6228f7
https://doi.org/10.1158/1078-0432.22479068.v1
https://doi.org/10.1158/1078-0432.22479068.v1
Autor:
Victor M. Villalobos, Anthony Tolcher, James P. Allison, Padmanee Sharma, Randy Robinson, James W. Purcell, Akshanth R. Polepally, Huibin Yue, Dominic W. Lai, Hua Fang, Chris Chen, Louie Naumovski, Vivek Subbiah, Alexander I. Spira, John D. Powderly, Antoine Hollebecque, Jason J. Luke, George D. Demetri
Supplementary Figure S2 shows LRRC15 RNA data from NanoString and clinical response in nonresponder (n=19) and responder (n=5) patients with sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e1099c95f3a5a148e0cf0c9c91a441
https://doi.org/10.1158/1078-0432.22479065.v1
https://doi.org/10.1158/1078-0432.22479065.v1
Autor:
Victor M. Villalobos, Anthony Tolcher, James P. Allison, Padmanee Sharma, Randy Robinson, James W. Purcell, Akshanth R. Polepally, Huibin Yue, Dominic W. Lai, Hua Fang, Chris Chen, Louie Naumovski, Vivek Subbiah, Alexander I. Spira, John D. Powderly, Antoine Hollebecque, Jason J. Luke, George D. Demetri
Supplementary Table S3 shows patient demographics and baseline characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596ca27dac132e213a281b945c1080b7
https://doi.org/10.1158/1078-0432.22479053.v1
https://doi.org/10.1158/1078-0432.22479053.v1
Autor:
Victor M. Villalobos, Anthony Tolcher, James P. Allison, Padmanee Sharma, Randy Robinson, James W. Purcell, Akshanth R. Polepally, Huibin Yue, Dominic W. Lai, Hua Fang, Chris Chen, Louie Naumovski, Vivek Subbiah, Alexander I. Spira, John D. Powderly, Antoine Hollebecque, Jason J. Luke, George D. Demetri
Supplementary Table S1 shows inclusion and exclusion criteria for each treatment arm that enrolled patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271adc4d902f52091fabcde75c704e43
https://doi.org/10.1158/1078-0432.22479059.v1
https://doi.org/10.1158/1078-0432.22479059.v1
Autor:
Victor M. Villalobos, Anthony Tolcher, James P. Allison, Padmanee Sharma, Randy Robinson, James W. Purcell, Akshanth R. Polepally, Huibin Yue, Dominic W. Lai, Hua Fang, Chris Chen, Louie Naumovski, Vivek Subbiah, Alexander I. Spira, John D. Powderly, Antoine Hollebecque, Jason J. Luke, George D. Demetri
Supplementary Figure S3 shows T-cell infiltration in patients with breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3d3a93d3d0519de697eca7b99fa362
https://doi.org/10.1158/1078-0432.22479062.v1
https://doi.org/10.1158/1078-0432.22479062.v1
Autor:
Vivek Subbiah, Louie Naumovski, Hua Fang, Antoine Hollebecque, George D. Demetri, Chris Chen, Victor M. Villalobos, Jason J. Luke, Alexander I. Spira, Padmanee Sharma, Dominic W. Lai, James P. Allison, James W. Purcell, Anthony W. Tolcher, Randy Robinson, Akshanth R. Polepally, Huibin Yue, John D. Powderly
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(13)
Purpose:Leucine-rich repeat containing 15 (LRRC15) is expressed on stromal fibroblasts in the tumor microenvironment of multiple solid tumor types and may represent an interesting target for therapy, particularly in patients with sarcomas where LRRC1
Autor:
Randy Robinson, Wanda Castro-Borrero, Sami Fam, Becky Parks, Douglas L. Arnold, Shan Xiao, Ludwig Kappos, Joan Holman, Stanley Cohan
Publikováno v:
Therapeutic Advances in Neurological Disorders
Therapeutic Advances in Neurological Disorders, Vol 14 (2021)
Therapeutic Advances in Neurological Disorders, Vol 14 (2021)
Background: EXTEND (NCT01797965), an open-label extension study, evaluated the safety and efficacy of daclizumab beta in participants with relapsing multiple sclerosis (MS) who had completed the randomized DECIDE study. Methods: Eligible participants
Publikováno v:
International Journal of MS Care. 19:141-147
Background: For patients with relapsing-remitting multiple sclerosis (RRMS) undergoing continuous immunomodulatory therapy, understanding whether vaccinations can be performed safely and effectively is important. We tested the immune response to inac
Autor:
Louie Naumovski, JuDee Fischer, Peter Ansell, Christine M. Bestvina, Joseph Thaddeus Beck, Amber Wong, Benedito A. Carneiro, Janet Yikai Jin, Einat Shacham Shmueli, Hui K Gan, Randy Robinson, Kyriakos P. Papadopoulos
Publikováno v:
Journal of Clinical Oncology. 38:TPS3649-TPS3649
TPS3649 Background: ABBV-321 (serclutamab talirine) is an epidermal growth factor receptor (EGFR)-targeted antibody-drug conjugate that consists of a humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD