Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Randy M Bruno"'
Publikováno v:
eLife, Vol 10 (2021)
Neocortical sensory areas have associated primary and secondary thalamic nuclei. While primary nuclei transmit sensory information to cortex, secondary nuclei remain poorly understood. We recorded juxtasomally from secondary somatosensory (POm) and v
Externí odkaz:
https://doaj.org/article/9f6f1becbeb44737be89b591505a3fe3
Autor:
Richard A Warren, Qianyun Zhang, Judah R Hoffman, Edward Y Li, Y Kate Hong, Randy M Bruno, Nathaniel B Sawtell
Publikováno v:
eLife, Vol 10 (2021)
Skilled motor behavior requires rapidly integrating external sensory input with information about internal state to decide which movements to make next. Using machine learning approaches for high-resolution kinematic analysis, we uncover the logic of
Externí odkaz:
https://doaj.org/article/32673067c59c48ae84788c9011dc1bd8
Autor:
Wanying Zhang, Randy M Bruno
Publikováno v:
eLife, Vol 8 (2019)
Layer (L) 2/3 pyramidal neurons in the primary somatosensory cortex (S1) are sparsely active, spontaneously and during sensory stimulation. Long-range inputs from higher areas may gate L2/3 activity. We investigated their in vivo impact by expressing
Externí odkaz:
https://doaj.org/article/aac4e55fc1c0455cac8323f4d8fcee26
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Activity in the superficial layers of the sensory cortex is believed to be largely driven by incoming sensory stimuli. Here the authors demonstrate how learning changes neural responses to sensations according to both behavioral relevance and timing,
Externí odkaz:
https://doaj.org/article/1ab7f442d9c34997ac4fe3397eaba62e
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2000-2008.e2 (2019)
Summary: The mammalian brain can form associations between behaviorally relevant stimuli in an animal’s environment. While such learning is thought to primarily involve high-order association cortex, even primary sensory areas receive long-range co
Externí odkaz:
https://doaj.org/article/3af0ff659f344830b7b2b9b3818695b1
Publikováno v:
Nature communications. 13(1)
Primary sensory cortex has long been believed to play a straightforward role in the initial processing of sensory information. Yet, the superficial layers of cortex overall are sparsely active, even during sensory stimulation; additionally, cortical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9056acb1d4922b473dbe33582b4b2b14
https://pubmed.ncbi.nlm.nih.gov/36127340
https://pubmed.ncbi.nlm.nih.gov/36127340
Primary sensory cortex has long been believed to play a straightforward role in the initial processing of sensory information. Yet, the superficial layers of cortex overall are sparsely active, even during sensory stimulation; moreover, cortical acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ada38d9a1780a1ade4d68a9b48f54c80
https://doi.org/10.1101/2021.12.23.474000
https://doi.org/10.1101/2021.12.23.474000
SUMMARYLearning alters cortical representations and improves perception. Apical tuft dendrites in Layer 1, which are unique in their connectivity and biophysical properties, may be a key site of learning-induced plasticity. We used both two-photon an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437d42bda996ac0ef7a6bcdafc537a28
https://doi.org/10.1101/2021.11.10.468144
https://doi.org/10.1101/2021.11.10.468144
Autor:
Jacob B. Dahan, Franck Polleux, Mario Dipoppa, Randy M. Bruno, Elizabeth M. C. Hillman, Ewoud R.E. Schmidt, Mauro M. Monsalve-Mercado, Jung M. Park, Hanzhi T. Zhao, Amélie Lejeune, Kenneth D. Miller, Chris C. Rodgers
Publikováno v:
Nature
The cognitive abilities that characterize humans are thought to emerge from unique features of the cortical circuit architecture of the human brain, which include increased cortico–cortical connectivity. However, the evolutionary origin of these ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580c94ba48ec06619f0ff10745b13e76
https://europepmc.org/articles/PMC9161439/
https://europepmc.org/articles/PMC9161439/