Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Randy F. Stout"'
Autor:
Raddy L. Ramos, Maider Michelena Beltran De Heredia, Yongwei Zhang, Randy F. Stout, Jaafar O. Tindi, Liching Wu, Gary J. Schwartz, Yair M. Botbol, Simone Sidoli, Ankita Poojari, Tammy Rakowski-Anderson, Bridget Shafit-Zagardo
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106594- (2024)
Aims: Cytoplasmic dynein heavy chain (DYNC1H1) is a multi-subunit protein complex that provides motor force for movement of cargo on microtubules and traffics them back to the soma. In humans, mutations along the DYNC1H1 gene result in intellectual d
Externí odkaz:
https://doaj.org/article/6c07a9ad44774ed0968d3018b7640dc1
Autor:
Ciaran Murphy-Royal, April D. Johnston, Andrew K. J. Boyce, Blanca Diaz-Castro, Adam Institoris, Govind Peringod, Oliver Zhang, Randy F. Stout, David C. Spray, Roger J. Thompson, Baljit S. Khakh, Jaideep S. Bains, Grant R. Gordon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Enduring changes in synaptic efficacy are highly sensitive to stress. Here, the authors show that astrocytic delivery of metabolites has an important role in the stress-mediated impairment of synaptic plasticity.
Externí odkaz:
https://doaj.org/article/a10e4cb6fa8941679643d05fade21f65
Autor:
Antonio Cibelli, Sandra Veronica Lopez-Quintero, Sean Mccutcheon, Eliana Scemes, David C. Spray, Randy F. Stout, Sylvia O. Suadicani, Mia M. Thi, Marcia Urban-Maldonado
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
We transduced mouse cortical astrocytes cultured from four litters of embryonic wildtype (WT) and connexin43 (Cx43) null mouse pups with lentiviral vector encoding hTERT and measured expression of astrocyte-specific markers up to passage 10 (p10). Th
Externí odkaz:
https://doaj.org/article/8040b483b6574b3d9e818fbff5a9e81b
Autor:
Ciaran Murphy-Royal, April D. Johnston, Andrew K. J. Boyce, Blanca Diaz-Castro, Adam Institoris, Govind Peringod, Oliver Zhang, Randy F. Stout, David C. Spray, Roger J. Thompson, Baljit S. Khakh, Jaideep S. Bains, Grant R. Gordon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/8bda98defbca4cc1bc9e39c6a3583bab
Autor:
Randy F. Stout, Elena Ivanova, Cyril G. Eleftheriou, Jakob Körbelin, Botir T. Sagdullaev, Carlo Corona
Publikováno v:
J Comp Neurol
Endothelial cells (ECs) are key players in the development and maintenance of the vascular tree, the establishment of the blood brain barrier and control of blood flow. Disruption in ECs is an early and active component of vascular pathogenesis. Howe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
Gap junction (GJ) channels permit molecules, such as ions, metabolites and second messengers, to transfer between cells. Their function is critical for numerous cellular interactions. GJ channels are composed of Connexin (Cx) hexamers paired across e
Autor:
Gerald Seifert, Antonio Cibelli, Guo P, Randy F. Stout, David C. Spray, Steinhaeuser C, Karen Maass, Eliana Scemes, de Menezes L, Aline Timmermann
The neurovascular unit (NVU) consists of cells intrinsic to the vessel wall, the endothelial cells and pericytes, and astrocyte endfeet that surround the vessel but are separated from it by basement membrane. Endothelial cells are primarily responsib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c937373f3c8a78059c0bbb26ed296d
https://doi.org/10.1101/2021.09.30.462547
https://doi.org/10.1101/2021.09.30.462547
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Glial cells of C. elegans can modulate neuronal activity and behavior, which is the focus of this review. Initially, we provide an overview of neuroglial evolution, making a comparison between C. elegans glia and their genealogical counterparts. What
Externí odkaz:
https://doaj.org/article/909089f5566b4ca59a9a45feb5f2af5a
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81771 (2013)
Transgene technology is one of the most heavily relied upon tools in modern biological research. Expression of an exogenous gene within cells, for research and therapeutic applications, nearly always includes promoters and other regulatory sequences.
Externí odkaz:
https://doaj.org/article/7ed541e8b3804b1a9688cf78240e341b
Autor:
Simran Bhatti, Kaihao Wang, Jerrin Peter, Randy F. Stout, Kaie Ojamaa, Adam Muncan, Shimin An, A. Martin Gerdes, Nimra Gilani, Yi-Da Tang, Khushbu Pandya, Youhua Zhang
Publikováno v:
J Mol Cell Cardiol
Subclinical hypothyroidism and low T3 syndrome are commonly associated with an increased risk of cardiovascular disease (CVD) and mortality. We examined effects of T3 on T-tubule (TT) structures, Ca2+ mobilization and contractility, and clustering of