Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Randy F Crossland"'
Autor:
Randy F Crossland, Alfred Balasa, Rajesh Ramakrishnan, Sangeetha K Mahadevan, Marta L Fiorotto, Ignatia B Van den Veyver
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201079 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0170127.].
Externí odkaz:
https://doaj.org/article/41363022c8d44a8d80a02d73aafeb9ed
Autor:
Randy F Crossland, Alfred Balasa, Rajesh Ramakrishnan, Sangeetha K Mahadevan, Marta L Fiorotto, Ignatia B Van den Veyver
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170127 (2017)
Offspring of murine dams chronically fed a protein-restricted diet have an increased risk for metabolic and neurobehavioral disorders. Previously we showed that adult offspring, developmentally exposed to a chronic maternal low-protein (MLP) diet, ha
Externí odkaz:
https://doaj.org/article/d8abca3f127a47bd8d7c07d465f9ef5d
Autor:
Forest R. Sheppard, Antoni R. Macko, James K. Aden, Randy F. Crossland, James E. Campbell, Alex Mitchell
Publikováno v:
Journal of Trauma and Acute Care Surgery. 80:610-616
BACKGROUND Heart rate (HR), systolic blood pressure (SBP) and mean arterial pressure (MAP) are traditionally used to guide patient triage and resuscitation; however, they correlate poorly to shock severity. Therefore, improved acute diagnostic capabi
Autor:
Eric E. Lloyd, Sharon C. Phillips, Robert M. Bryan, Randy F. Crossland, David J. Durgan, Sean P. Marrelli, Anilkumar K. Reddy
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 305:R334-R342
Obstructive sleep apnea (OSA), a condition in which the upper airway collapses during sleep, is strongly associated with metabolic and cardiovascular diseases. Little is known how OSA affects the cerebral circulation. The goals of this study were 1)
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 37(8)
Circadian clock components oscillate in cells of the cardiovascular system. Disruption of these oscillations has been observed in cardiovascular diseases. We hypothesized that obstructive sleep apnea, which is associated with cerebrovascular diseases
Autor:
James K. Aden, Antoni R. Macko, Forest R. Sheppard, Alexander J. Burdette, Ruth Madelaine Paredes, Randy F. Crossland
Publikováno v:
Shock (Augusta, Ga.). 46(3 Suppl 1)
BACKGROUND Uncontrolled hemorrhage (UH), the leading cause of potentially survivable combat-related death, elicits a deleterious inflammatory response. Our group previously reported an increased secretion of pro-inflammatory cytokines in a novel non-
Autor:
Darren M. Fryer, Forest R. Sheppard, Thomas A. Mitchell, Antoni R. Macko, Randy F. Crossland, Andrew P. Cap, Anthony E. Pusateri
Publikováno v:
The journal of trauma and acute care surgery. 80(4)
BACKGROUND Hemorrhage remains the leading cause of potentially survivable trauma mortality. Recent reports indicate that injuries sustained in noncompressible anatomic locations (i.e., truncal and junctional) account for 86.5% of hemorrhage-related d
Autor:
George E. Taffet, Craig J. Hartley, Khodadad Namiranian, Robert M. Bryan, Randy F. Crossland, Eric E. Lloyd, Anilkumar K. Reddy, Sean P. Marrelli
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 299:R461-R469
We tested the hypothesis that TREK-1, a two-pore domain K channel, is involved with dilations in arteries. Because there are no selective activators or inhibitors of TREK-1, we generated a mouse line deficient in TREK-1. Endothelium-mediated dilation
Publikováno v:
The FASEB Journal. 29
Background: Restoration of oxygen carrying capacity (OCC) is essential to adequately treat hemorrhagic shock. Multifunctional resuscitation fluids (MRFs) containing oxygen carrier (OC) molecules are being developed to improve OCC. However, adverse va
Autor:
Alexander K. Brown, Darren M. Fryer, Forest R. Sheppard, Douglas K. Tadaki, Randy F. Crossland, Antoni Macko, Kassandra M. Ozuna
Publikováno v:
Shock (Augusta, Ga.). 44
Hemorrhage is the leading cause of potentially survivable trauma mortality, necessitating the development of improved therapeutic interventions. The objective of this study was to develop and characterize a reproducible clinically translatable nonhum