Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Randy D. Rutkowske"'
Publikováno v:
Magnetic Resonance in Chemistry. 46:558-563
We describe here new versions of the DEPT phase-encoded HMQC experiment that offer robust performance and improved sensitivity. The new sequences rely on frequency-swept proton and carbon pulses to minimize signal losses from miscalibrated pulses whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a32033a5ffa744390bec9e562dabe87
https://doi.org/10.1002/mrc.2214
https://doi.org/10.1002/mrc.2214
Publikováno v:
Magnetic Resonance in Chemistry. 46:564-570
This article describes new versions of the DEPT phase-edited heteronuclear single quantum correlation (HSQC) pulse sequence with sensitivity enhancement. The sequences incorporate frequency-swept carbon and proton pulses. The new experiments are inhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51915741f1a6f21d52c448cd78de62af
https://doi.org/10.1002/mrc.2215
https://doi.org/10.1002/mrc.2215
Autor:
Randy D. Rutkowske, Sergey S. Golotvin, Antony J. Williams, Timothy D. Spitzer, Brent A. Lefebvre, Rostislav Pol, Eugene Vodopianov
Publikováno v:
Magnetic Resonance in Chemistry. 45:803-813
A method for structure validation based on the simultaneous analysis of a 1D 1H NMR and 2D 1H13C single-bond correlation spectrum such as HSQC or HMQC is presented here. When compared with the validation of a structure by a 1D 1H NMR spectrum alone,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8063258fc4d9acaad1567e6a8d5e16
https://doi.org/10.1002/mrc.2034
https://doi.org/10.1002/mrc.2034
Publikováno v:
Synlett. :1394-1398
A stereoselective synthesis of 2-carbonitrile and 2-aminomethyl-substituted 5-phenylbenzazepine derivatives was developed starting from [4-hydroxy-3-(methyloxy)phenyl]acetic acid. The key step in the synthesis is a stereoselective addition of cyanide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398d8796fd4a367cfd3fe839b2008e5e
https://doi.org/10.1055/s-2004-825618
https://doi.org/10.1055/s-2004-825618
Publikováno v:
Magnetic Resonance in Chemistry. 39:539-543
Two new pulse sequences are presented for the acquisition of DEPT–HMQC spectra, based on the original experiment of Kessler et al. The new sequences employ modifications intended to make the experiment well suited for high-throughput acquisition an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98a1f83fbd2972224f519f5093a4641d
https://doi.org/10.1002/mrc.883
https://doi.org/10.1002/mrc.883
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4a35c1aa6be94b7869287f55ed854d
https://doi.org/10.1002/chin.199611199
https://doi.org/10.1002/chin.199611199
Autor:
Royston C. B. Copley, Szewczyk Jerzy Ryszard, Randy D. Rutkowske, Luke A. D. Miller, Douglas J. Minick
Publikováno v:
Chirality. 19(9)
GT-2331 [(+)-1] is one of the most potent members of a class of chiral drug substances used to regulate the synthesis and release of histamine by the histamine H3 receptor, and as such, is an important biomarker for pharmaceutical companies conductin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c81d68ace99fac147c1bc6865591f18
https://pubmed.ncbi.nlm.nih.gov/17575572
https://pubmed.ncbi.nlm.nih.gov/17575572
Publikováno v:
ChemInform. 35
A stereoselective synthesis of 2-carbonitrile and 2-aminomethyl-substituted 5-phenylbenzazepine derivatives was developed starting from [4-hydroxy-3-(methyloxy)phenyl]acetic acid. The key step in the synthesis is a stereoselective addition of cyanide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a12da62f0e1798c89a0579513bf02d
https://doi.org/10.1002/chin.200445187
https://doi.org/10.1002/chin.200445187
Autor:
Ronda G. Davis-Ward, Andrew Spaltenstein, C. Webster Andrews, Ronald George Sherrill, Randy D. Rutkowske, Lois L. Wright, William J. Bock, Richard J. Hazen, Furfine Eric Steven
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(1)
Optimization of P1-substituted pyrrolidinone based HIV protease inhibitors has yielded analogs with very potent antiviral activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ecf083146eceeb459f4f4fa34b712c2
https://pubmed.ncbi.nlm.nih.gov/15582415
https://pubmed.ncbi.nlm.nih.gov/15582415
Publikováno v:
The Journal of Organic Chemistry. 60:7063-7065
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7300f2bc7f5f07d211c1f8a18a9319ba
https://doi.org/10.1021/jo00126a077
https://doi.org/10.1021/jo00126a077