Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Randy, Caliliw"'
Autor:
Noah Trac, Hyun Seok Oh, Leila Izzy Jones, Randy Caliliw, Shinji Ohtake, Brian Shuch, Eun Ji Chung
Publikováno v:
Molecules, Vol 27, Iss 23, p 8457 (2022)
The majority of clear cell renal cell carcinomas (ccRCCs) are characterized by mutations in the Von Hippel–Lindau (VHL) tumor suppressor gene, which leads to the stabilization and accumulation of the HIF2α transcription factor that upregulates key
Externí odkaz:
https://doaj.org/article/29cb2d18a90548f181d9087a1dd0b060
Autor:
Lin Lin, Neal Patel, Blake Wilde, Lucia Fernandez-del-Rio, Eirini Christodoulou, Shinji Ohtake, Randy Caliliw, Orian Shirihai, Xiaowu Gai, Heather Christofk, David Shackelford, Brian Shuch
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12eaf3ef20272c397e6e9f0afd618e9f
https://doi.org/10.1097/ju.0000000000003272.02
https://doi.org/10.1097/ju.0000000000003272.02
Autor:
Daiki Ueno, Juan C. Vasquez, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Sam Friedman, Randy Caliliw, Shinji Ohtake, Xun Bao, Jing Li, Huihui Ye, Karla Boyd, Rong Rong Huang, Jack Dodson, Paul Boutros, Ranjit S. Bindra, Brian Shuch
Publikováno v:
Oncotarget, vol 13, iss 1
Loss-of-function mutations in genes encoding the Krebs cycle enzymes Fumarate Hydratase (FH) and Succinate Dehydrogenase (SDH) induce accumulation of fumarate and succinate, respectively and predispose patients to hereditary cancer syndromes includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bdace8f551663a705132bbe1be851c
https://escholarship.org/uc/item/3nj6b2ht
https://escholarship.org/uc/item/3nj6b2ht
Autor:
Daiki Ueno, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Randy Caliliw, Huihui Ye, Rong Rong Huang, Jing Li, Karla Boyd, Ranjit S. Bindra, Juan C. Vasquez, Brian M. Shuch
Publikováno v:
Molecular Cancer Therapeutics. 20:P055-P055
Loss-of-function mutations in genes encoding the Krebs cycle enzymes fumarate hydratase (FH) and succinate dehydrogenase (SDH) lead to excess accumulation of fumarate and succinate, respectively. Germline mutations in FH lead to a genetic predisposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c564a9f8e91cfe714d857aea04856665
https://doi.org/10.1158/1535-7163.targ-21-p055
https://doi.org/10.1158/1535-7163.targ-21-p055
Autor:
Allan J. Pantuck, Fairooz F. Kabbinavar, Michela de Martino, Arie S. Belldegrun, Jeffrey LaRochelle, Randy Caliliw, Brian Shuch, Tobias Klatte, Zhenhua Li, David Seligson
Publikováno v:
Journal of Urology. 182:728-734
We assessed CA9 single nucleotide polymorphisms and mutations, and their association with CAIX protein expression, overall survival and response to interleukin-2 in white patients with metastatic clear cell renal cell carcinoma.Genomic DNA was extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b758da677756d71a683887339b78ce09
https://doi.org/10.1016/j.juro.2009.03.077
https://doi.org/10.1016/j.juro.2009.03.077
Autor:
Gang Zeng, Nicolette Janzen, John T. Leppert, Randy Caliliw, Robert A. Figlin, Oleg Shvarts, Arie S. Belldegrun, John S. Lam
Publikováno v:
Urology. 68:1132-1138
Objectives Carbonic anhydrase-IX (CA-IX) is a cell surface tumor-associated antigen expressed by most clear cell renal cell carcinomas (RCCs). The specificity and the prognostic value of CA-IX provide impetus to create a mouse model of CA-IX-expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795d4a78ece3649c2c7e6da07e6ba15a
https://doi.org/10.1016/j.urology.2006.08.1073
https://doi.org/10.1016/j.urology.2006.08.1073
Autor:
Allan J. Pantuck, Randy Caliliw, Arie S. Belldegrun, Jean B. deKernion, Scott Sheriff, Amnon Zisman, Belur J. Patel, Cho-Lea Tso, Lily Wu, Ke-Hung Tsui, Sun H. Paik
Publikováno v:
Journal of Urology. 164:1420-1425
Purpose: The mechanisms responsible for tumor progression to androgen independence in prostate cancer (CaP) remain unknown. To characterize these changes and provide a basis for rational therapeutic strategies for advanced CaP, an in vivo model from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41117f0db9a82dff59cbc4c88e2d4d30
https://doi.org/10.1016/s0022-5347(05)67210-2
https://doi.org/10.1016/s0022-5347(05)67210-2
Autor:
Jose M. Hernandez, Randy Caliliw, Arie S. Belldegrun, John S. Lam, Robert A. Figlin, Hideki Mukouyama, Allen Y. Wang, Nicolette Janzen, Gang Zeng
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(4)
Purpose: Carbonic anhydrase 9 (CA9) is the most promising molecular marker described for renal cell carcinoma (RCC) to date. We investigated whether transduction of monocytes from peripheral blood with adenovirus encoding the CA9 gene (AdV-CA9) could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f02e4d64a11d44c9d019e76ea8d418c
https://pubmed.ncbi.nlm.nih.gov/14977845
https://pubmed.ncbi.nlm.nih.gov/14977845
Autor:
José M, Hernández, Matthew H T, Bui, Ken-Ryu, Han, Hideki, Mukouyama, Danielo G, Freitas, David, Nguyen, Randy, Caliliw, Peter I, Shintaku, Sun H, Paik, Cho-Lea, Tso, Robert A, Figlin, Arie S, Belldegrun
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(5)
We investigated the ability of the fusion protein granulocyte-macrophage colony-stimulating factor and carbonic anhydrase IX (GMCA-9)(1) to induce an immune response in vitro and in vivo for the development of a GMCA-9-based kidney cancer vaccine.Hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a47c440e659cface292bb1ac37e009cb
https://pubmed.ncbi.nlm.nih.gov/12738749
https://pubmed.ncbi.nlm.nih.gov/12738749
Immunosensitization of resistant human tumor cells to cytotoxicity by tumor infiltrating lymphocytes
Publikováno v:
International Journal of Oncology.
Most anti-cancer therapies induce apoptotic cell death, but a major barrier to long-term cancer treatments is the generation of apoptosis-resistant tumor cells. Tumor cells that become resistant to one therapy are usually cross-resistant to subsequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1103beb686b0e3f1030b865bc0b30792
https://doi.org/10.3892/ijo.22.2.431
https://doi.org/10.3892/ijo.22.2.431