Zobrazeno 1 - 10
of 1 801
pro vyhledávání: '"Rands, E"'
Autor:
Piffero, Luiza de Menezes
Publikováno v:
Biblioteca Digital de Teses e Dissertações da UFRGSUniversidade Federal do Rio Grande do SulUFRGS.
A presente pesquisa problematiza a noção de paisagem na arte contemporânea a partir da fotografia. Para tanto, analisa trabalhos fotográficos de três artistas: Efêmera Paisagem, do paraense Alberto Bitar, West Solent Coastline Rhythm, do inglê
Externí odkaz:
http://hdl.handle.net/10183/122554
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1970 Dec . 67(4), 1789-1796.
Externí odkaz:
https://www.jstor.org/stable/60570
Autor:
S J deSolms, Rands E, Jackson B. Gibbs, Catherine M. Wiscount, Scholz Th, Robert L. Smith, Kenneth S. Koblan, Nancy E. Kohl, E A Giuliani, David L. Pompliano, Scott D. Mosser, Oliff Allen I, Samuel L. Graham
Publikováno v:
Journal of Medicinal Chemistry. 41:2651-2656
Inhibitors of Ras protein farnesyltransferase are described which are reduced pseudopeptides related to the C-terminal tetrapeptide of the Ras protein that signals farnesylation. Reduction of the carbonyl groups linking the first three residues of th
Autor:
Theresa M. Williams, Rands E, Nancy E. Kohl, George D. Hartman, Samuel L. Graham, Kelly Hamilton, Timothy J. O'Neill, Oliff Allen I, Christopher J. Dinsmore, Kenneth S. Koblan, Jackson B. Gibbs
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:1345-1348
The design and synthesis of simple nonpeptide inhibitors of farnesyl-protein transferase (FTase) are described. Cysteine-derived diarylether frameworks are appropriate structural replacements for the C -terminal tetrapeptide portion of the Ras protei
Autor:
Dona L. Bamberger, Jackson B. Gibbs, Oliff Allen I, Nancy E. Kohl, Samuel L. Graham, Rands E, Thorsten E. Fisher, Robert L. Smith, Scott D. Mosser, John S. Wai, David L. Pompliano
Publikováno v:
Bioorganic & Medicinal Chemistry. 2:939-947
Replacement of the central amino methylene linkage of C[psi CH2NH]A[psi CH2NH]AX tetrapeptide inhibitors with carbon tethers led to compounds with potency in the nanomolar range. Some of the more potent olefinic compounds inhibit Ras processing in in
Autor:
Michael J. Breslin, Samuel L. Graham, Scott D. Mosser, Deana Aa, Rands E, Oliff Allen I, S J deSolms, Nancy E. Kohl, David L. Pompliano, E A Giuliani
Publikováno v:
Journal of Medicinal Chemistry. 37:725-732
Inhibitors of Ras farnesyl-protein transferase are described. These are reduced pseudopeptides related to the C-terminal tetrapeptide of the Ras protein that signals farnesylation. Deletion of the carbonyl groups between the first two residues of the
Autor:
Sarkar, Anushka1 (AUTHOR), Hildebrandt, Emily R1 (AUTHOR), Patel, Khushi V1 (AUTHOR), Mai, Emily T1 (AUTHOR), Shah, Sumil A1 (AUTHOR), Kim, June H1 (AUTHOR), Schmidt, Walter K1 (AUTHOR) wschmidt@uga.edu
Publikováno v:
G3: Genes | Genomes | Genetics. Aug2024, Vol. 14 Issue 8, p1-14. 14p.
Autor:
Galenko-Yaroshevsky, Pavel A.1 galenko.yarochevsky@gmail.com, Torshin, Ivan Yu.2 tiy135@yahoo.com, Gromov, Andrei N.2 gromlogin@gmail.com, Reyer, Ivan A.2 reyer@forecsys.ru, Gromova, Olga A.2 unesco.gromova@gmail.com, Glechyan, Tereza R.1 t_g91@mail.ru, Suzdalev, Konstantin F.3 konsuz@gmail.com, Zadorozhniy, Andrey V.4 stomvr1@gmail.com, Zelenskaya, Anait V.1 anait_06@mail.ru
Publikováno v:
Research Results in Pharmacology. 2024, Vol. 10 Issue 3, p1-9. 9p.
Autor:
Scott D. Mosser, Sheo B. Singh, Russell B. Lingham, Jackson B. Gibbs, Rands E, Edward M. Scolnick, David L. Pompliano, Oliff Allen I, Nancy E. Kohl
Publikováno v:
Journal of Biological Chemistry. 268:7617-7620
The ras oncogene product, Ras, is synthesized in vivo as a precursor protein that requires post-translational processing to become biologically active and to be capable of transforming mammalian cells. Farnesylation appears to be a critical modificat
Autor:
Robert B. Lobell, J. Christopher Culberson, Jackson B. Gibbs, Christopher J. Dinsmore, Kenneth S. Koblan, Theresa M. Williams, Nancy E. Kohl, Dongming Liu, Rands E, Timothy J. O'Neill
Publikováno v:
ChemInform. 31