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pro vyhledávání: '"Randolph D. Thompson"'
Publikováno v:
Archives of Toxicology. 68:332-337
Over the past 40 years, toxicologists and pharmacologists have used tables published by Weil for the determination of LD50 (or ED50) values and their associated 95% confidence intervals. With the advances in computer technology, it is now common for
Publikováno v:
Archives of Toxicology. 67:478-490
A system was developed for exposure of unanesthetized mice to airborne chemicals and for continuous measurement of their breathing pattern prior to, during and following exposure. By measuring inspiratory and expiratory airflows (VI and VE), and inte
Publikováno v:
American Industrial Hygiene Association journal. 55(10)
Mice were exposed to thermal decomposition products (TDP) released from acrylonitrile butadiene styrene (ABS), polypropylene-polyethylene copolymer (CP), polypropylene homopolymer (HP), or plasticized polyvinylchloride (PVC). These resins were heated
Autor:
Randolph D. Thompson, M.F. Stock, Lee Ann Boylstein, Michelle Schaper, Yves Alarie, J. E. Luo, Rajagopalan Vijayaraghavan
Publikováno v:
Archives of toxicology. 68(8)
The pattern and timing of a normal breath in unanesthetized mice was analyzed from measurement of inspiratory and expiratory airflows (VI and VE). Airflow was measured via a differential pressure transducer, attached to a pneumotachograph, which itse
Publikováno v:
Toxicology and applied pharmacology. 79(2)
Guinea pigs inhaling 10% CO2, 19% O2, and 71 N2 increase their tidal volume (VT) by a factor of 2 to 3 and their respiratory frequency (f) by a factor of 1.2 to 1.5 above their normal values while breathing room air. While exposing guinea pigs to 10%