Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Randolf, Kerschbaumer"'
Autor:
Barbara Maurer, Irina Mirkina, Julia Mayer, Christine Landlinger, Alexander Schinagl, Michael Thiele, Randolf Kerschbaumer
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf31c0b2bb5395cdecfb8f77db373fa
https://doi.org/10.1136/jitc-2022-sitc2022.1059
https://doi.org/10.1136/jitc-2022-sitc2022.1059
Autor:
Peter Goettig, Julia Hollerweger, Peter Scholz, Dirk Voelkel, Hans Brandstetter, Patrice Douillard, Nicolas Sabarth, Randolf Kerschbaumer, Friedrich Scheiflinger, Alexander Schinagl, Michael Thiele
Publikováno v:
Biochemistry. 57:1523-1532
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory and tumor-promoting cytokine that occurs in two redox-dependent immunologically distinct conformational isoforms. The disease-related structural isoform of MIF (oxMIF) can be specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc29482d441d76423d11bab395a40e0
https://doi.org/10.1021/acs.biochem.7b01156
https://doi.org/10.1021/acs.biochem.7b01156
Autor:
Daniel Fleischanderl, Randolf Kerschbaumer, Gerhard Antoine, Dirk Voelkel, Peter Matthiessen, Nicolas Sabarth, Friedrich Scheiflinger, Patrice Douillard, Michael Freissmuth, Michael Thiele
Publikováno v:
Antibodies
Volume 8
Issue 3
Antibodies, Vol 8, Iss 3, p 46 (2019)
Volume 8
Issue 3
Antibodies, Vol 8, Iss 3, p 46 (2019)
Efficacy, safety, and manufacturability of therapeutic antibodies are influenced by their biopharmaceutical and biophysical properties. These properties can be optimized by library approaches or rationale protein design. Here, we employed a protein e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58f3dbe83a16ee4043b1ac1da0e532d
Autor:
Patrice Douillard, Lukas Kenner, Michael Thiele, Randolf Kerschbaumer, Dirk Völkel, Zahra Kazemi, Alexander Schinagl, Friedrich Scheiflinger, Michael Freissmuth
Publikováno v:
Oncotarget
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine, which was shown to be upregulated in cancers and to exhibit tumor promoting properties. Unlike other cytokines, MIF is ubiquitously present in the circulation and tissue of healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed4e25514961c6810005a3c9e3642b6
http://europepmc.org/articles/PMC5341993
http://europepmc.org/articles/PMC5341993
Autor:
Michael Thiele, Patrick Thurner, Dirk Völkel, Filza Hussain, Randolf Kerschbaumer, Patrice Douillard, Hartmut J. Ehrlich, Friedrich Scheiflinger, Gerhard Antoine, Michael Freissmuth, Hans-Peter Schwarz
Publikováno v:
Molecular Cancer Therapeutics. 12:1223-1234
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine, originally discovered for its eponymous effect and now known for pleiotropic biologic properties in immunology and oncology. Circulating MIF levels are elevated in several ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387ff33028dd40cb857b21f12ba97552
https://doi.org/10.1158/1535-7163.mct-12-0988
https://doi.org/10.1158/1535-7163.mct-12-0988
Autor:
Jurate Garbaraviciene, Thierry Calandra, Gerhard Antoine, Didier Le Roy, Wolf-Henning Boehncke, Michael Thiele, Clive R. Wood, Hartmut J. Ehrlich, Randolf Kerschbaumer, Thierry Roger, Manfred Rieger, Dirk Völkel, Jürgen Müllberg, Rene Hoet, Michael Dockal, Friedrich Scheiflinger, Helga Savidis-Dacho
Publikováno v:
The Journal of biological chemistry
JOURNAL OF BIOLOGICAL CHEMISTRY
Journal of Biological Chemistry, Vol. 287, No 10 (2012) pp. 7446-7455
JOURNAL OF BIOLOGICAL CHEMISTRY
Journal of Biological Chemistry, Vol. 287, No 10 (2012) pp. 7446-7455
The macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that recently emerged as an attractive therapeutic target for a variety of diseases. A diverse panel of fully human anti-MIF antibodies was generated by selection from a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd75e6ea654d84e80bd66d12ab78738a
https://doi.org/10.1074/jbc.m111.329664
https://doi.org/10.1074/jbc.m111.329664
Autor:
Erica Magelky, Michael Thiele, Manfred Rieger, Hartmut J. Ehrlich, Frederick W.K. Tam, Mei-Ching Yu, John P. McDaid, Bernd Jilma, Friedrich Scheiflinger, Cox Terhorst, Alexander R. Moschen, Alexander Schinagl, Geert C. Mudde, Herbert Tilg, Randolf Kerschbaumer, Jennifer Smith, Atul K. Bhan, H. Terence Cook, Charles D. Pusey, Patrice Douillard, Harald Kühnel, Josef Kovarik, Dirk Völkel, G. Bhangal
Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine and counterregulator of glucocorticoids, is a potential therapeutic target. MIF is markedly different from other cytokines because it is constitutively expressed, stored in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87c3d184f5938784d2b75f1a157050b
https://europepmc.org/articles/PMC4543907/
https://europepmc.org/articles/PMC4543907/
Autor:
Peter Turecek, Meinhard Hasslacher, Herbert Gritsch, Friedrich Scheiflinger, Klaus Zimmermann, Michael Dockal, Hans Peter Schwarz, Randolf Kerschbaumer, Simone M. Schatz, Friedrich Dorner
Publikováno v:
British Journal of Haematology. 125:629-637
The C2 domain of factor VIII (FVIII) is important for FVIII-phospholipid (PL) and FVIII-von Willebrand factor (VWF) interactions. A FVIII structural model, derived by electron crystallography, suggests four hydrophobic loops at the FVIII C2 domain-PL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22245825f1de990c1214d0bf82c562ef
https://doi.org/10.1111/j.1365-2141.2004.04959.x
https://doi.org/10.1111/j.1365-2141.2004.04959.x
Autor:
Friedrich Scheiflinger, Simone M. Schatz, Friedrich Dorner, Randolf Kerschbaumer, Gabriele Gerstenbauer, Martina Kral
Publikováno v:
Biotechnology and Bioengineering. 84:433-438
A chimeric Fab was expressed in Chinese hamster ovary cells under the control of the CMV promoter in a two-stage production process. Cells were first grown to 90% confluence at 37 degrees C in a proliferation phase, followed by a production phase at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0884fefd182535c0c6933ad4646d21
https://doi.org/10.1002/bit.10793
https://doi.org/10.1002/bit.10793
Autor:
Jasgit C. Sachdev, Ramesh K. Ramanathan, X. Liu, Apostolia-Maria Tsimberidou, Lowell L. Hart, Deyaa Adib, Salim Yazji, Manish R. Patel, Dirk Jäger, G.Ç. Manzur, John Sarantopoulos, M. Yoon, Niels Halama, Devalingam Mahalingam, Randolf Kerschbaumer
Publikováno v:
Annals of Oncology. 27:vi116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77c131cbb3430723bab2a4281dfe6d08
https://doi.org/10.1093/annonc/mdw368.08
https://doi.org/10.1093/annonc/mdw368.08