Pesticide chlorpyrifos acts as an endocrine disruptor in adult rats causing changes in mammary gland and hormonal balance

Autor: Ventura, Clara, Ramos Nieto, María Rosa, Bourguignon, Nadia, Lux, Victoria Adela R., Rodriguez, Horacio Adolfo, Cao, Gabriel Fernando, Randi, Andrea Silvana, Cocca, Claudia Marcela, Núñez, Mariel Alejandra

Endocrine disruptors (EDs) are compounds that interfere with hormone regulation and influence mammary carcinogenesis. We have previously demonstrated that the pesticide chlorpyrifos (CPF) acts as an ED in vitro, since it induces human breast cancer c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3498::caa996888134b4153f907a8c57fcce9d
https://www.sciencedirect.com/science/article/abs/pii/S0960076015301126

Mechanism of action of hexachlorobenzene no growth factors receptors signal transduction pathway in rat liver

Autor: Randi, Andrea Silvana

Publikováno v: Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN

Elhexaclorobenceno (HCB)es un tóxico ambiental ampliamente distribuidoen la biósfera. La exposición crónica de animales de laboratorio al HCB,produce porfiria, inducción de enzimas microsomales hepáticas, disfuncionestiroideas, inmunosupresión

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::255b8a313d5fc4cb033c325c4691bd25

Hexachlorobenzene promotes angiogenesis in vivo, in a breast cancer model and neovasculogenesis in vitro, in the human microvascular endothelial cell line HMEC-1.

Autor: Pontillo, Carolina¹ caroponti@hotmail.com, Español, Alejandro² aespan_1999@yahoo.com, Chiappini, Florencia^1,2 florenciachiappini@hotmail.com, Miret, Noelia¹ noeliamiret@hotmail.com.ar, Cocca, Claudia³ cm_cocca@hotmail.com, Alvarez, Laura¹ laura6alvarez@yahoo.com.ar, Kleiman de Pisarev, Diana¹ dianakleiman@yahoo.com.ar, Sales, María Elena² malegazpio@yahoo.com.ar, Randi, Andrea Silvana¹ andybiol@yahoo.com.ar

Publikováno v: Toxicology Letters. Nov2015, Vol. 239 Issue 1, p53-64. 12p.

Action of endocrine disruptors in breast cancer - Role of the transforming growth factor-beta 1 and the aryl hydrocarbon receptor

Autor: Miret, Noelia Victoria

Publikováno v: Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

La incidencia de cáncer de mama está aumentando a nivel mundial y la exposición a disruptores endocrinos ha cobrado importancia, como un potencial factor de riesgo. El Hexaclorobenceno (HCB) fue utilizado como fungicida y, a pesar de estar prohibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::70c20f31d18ccbdad31cfe1b76ef2d37

Hexachlorobenzene as a differential modulator of the conventional and metronomic chemotherapy response in triple negative breast cancer cells.

Autor: Sanchez Y; Center of Pharmacological and Botanical Studies (CEFYBO)-National Council for Science and Technology (CONICET)-University of Buenos Aires, Buenos Aires C1121ABG, Argentina., Vasquez Callejas MA; Center of Pharmacological and Botanical Studies (CEFYBO)-National Council for Science and Technology (CONICET)-University of Buenos Aires, Buenos Aires C1121ABG, Argentina., Miret NV; Laboratory of Biological Effects of Environmental Pollutants, Department of Human Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires C1121ABG, Argentina., Rolandelli G; Center of Pharmacological and Botanical Studies (CEFYBO)-National Council for Science and Technology (CONICET)-University of Buenos Aires, Buenos Aires C1121ABG, Argentina., Costas C; Center of Pharmacological and Botanical Studies (CEFYBO)-National Council for Science and Technology (CONICET)-University of Buenos Aires, Buenos Aires C1121ABG, Argentina., Randi AS; Laboratory of Biological Effects of Environmental Pollutants, Department of Human Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires C1121ABG, Argentina., Español A; Center of Pharmacological and Botanical Studies (CEFYBO)-National Council for Science and Technology (CONICET)-University of Buenos Aires, Buenos Aires C1121ABG, Argentina.; Department of Pharmacology, School of Medicine, University of Buenos Aires, Buenos Aires C1121ABG, Argentina.

Publikováno v: Exploration of targeted anti-tumor therapy [Explor Target Antitumor Ther] 2024; Vol. 5 (2), pp. 278-295. Date of Electronic Publication: 2024 Mar 21.