Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies

Autor: Mann, Graham J., Cust, Anne E., Schmid, Helen, Hopper, John L., Aitken, Joanne F., Armstrong, Bruce K., Giles, Graham G., Holland, Elizabeth, Kefford, Richard F., Jenkins, Mark A., Newton Bishop, Julia A., Affleck, Paul, Barrett, Jennifer H., Bishop, D. Timothy, Harrison, Jane, Iles, Mark M., Randerson-Moor, Juliette, Harland, Mark, Taylor, John C., Whittaker, Linda, Kukalizch, Kairen, Leake, Susan, Karpavicius, Birute, Haynes, Sue, Mack, Tricia, Chan, May, Taylor, Yvonne, Davies, John, King, Paul, Drummond, Martin, Kanetsky, Peter A., Goldstein, Alisa M., MacGregor, Stuart, Law, Matthew H., Bui, Minh, Brossard, Myriam, Demenais, Florence, Hoggart, Clive, Brown, Kevin M., Landi, Maria Teresa, Newton-Bishop, Julia A.

Publikováno v: In Journal of Investigative Dermatology December 2018 138(12):2617-2624

The determinants of serum vitamin D levels in participants in a melanoma case-control study living in a temperate climate

Autor: Davies, John R., Chang, Yu-Mei, Snowden, Helen, Chan, May, Leake, Susan, Karpavicius, Birute, Haynes, Sue, Kukalizch, Kairen, Randerson-Moor, Juliette, Elliott, Faye, Barth, Julian, Kanetsky, Peter A., Harland, Mark, Bishop, D. Timothy, Barrett, Jennifer H., Newton-Bishop, Julia A.

Publikováno v: Cancer Causes & Control, 2011 Oct 01. 22(10), 1471-1482.

Externí odkaz: https://www.jstor.org/stable/41485232

β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas

Autor: Nsengimana, Jérémie, Laye, Jon, Filia, Anastasia, O’Shea, Sally, Muralidhar, Sathya, Poźniak, Joanna, Droop, Alastair, Chan, May, Walker, Christy, Parkinson, Louise, Gascoyne, Joanne, Mell, Tracey, Polso, Minttu, Jewell, Rosalyn, Randerson-Moor, Juliette, Cook, Graham P., Bishop, D. Timothy, Newton-Bishop, Julia

Publikováno v: The Journal of Clinical Investigation

Immunotherapy prolongs survival in only a subset of melanoma patients, highlighting the need to better understand the driver tumor microenvironment. We conducted bioinformatic analyses of 703 transcriptomes to probe the immune landscape of primary cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a831d062399dabd3e897ec41507d7609
http://europepmc.org/articles/PMC5919828

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Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Autor: Duffy, David L., Zhu, Gu, Li, Xin, Sanna, Marianna, Jacobs, Leonie C., Evans, David M., Yazar, Seyhan, Beesley, Jonathan, Lawrence, Matthew H., Kraft, Peter, Visconti, Alessia, Taylor, John C., Lui, Fan, Wright, Margaret J., Henders, Anjali K., Bowdler, Lisa, Glass, Dan, Ikram, Arfan M., Uitterlinden, André G., Madden, Pamela A., Heath, Andrew C., Nelson, Elliot C., Green, Adele C., Chanock, Stephen, Barrett, Jennifer H., Brown, Matthew A., Hayward, Nicholas K., MacGregor, Stuart, Sturm, Richard A., Hewitt, Alex W., Leenhardt, Jeffrey E., Brossard, Myriam, Moses, Eric K., Song, Fengju, Kumar, Rajiv, Easton, Douglas F., Pharoah, Paul D. P., Swerdlow, Anthony J., Kypreou, Katerina P., Harland, Mark, Randerson-Moor, Juliette, Akslen, Lars A., Andresen, Per A., Avril, Marie-Françoise, Azizi, Esther, Scarrà, Giovanna Bianchi, Brown, Kevin M., Dębniak, Tadeusz, Elder, David E., Fang, Shenying, Friedman, Eitan, Galan, Pilar, Ghiorzo, Paola, Gillanders, Elizabeth M., Goldstein, Alisa M., Gruis, Nelleke A., Hansson, Johan, Helsing, Per, Hočevar, Marko, Höiom, Veronica, Ingvar, Christian, Kanetsky, Peter A., Chen, Wei V., Landi, Maria Teresa, Lang, Julie, Lathrop, G. Mark, Lubiński, Jan, Mackie, Rona M., Mann, Graham J., Molven, Anders, Novaković, Srdjan, Olsson, Håkan, Puig, Susana, Puig-Butille, Joan Anton, Radford-Smith, Graham L., van Doorn, Remco, Whiteman, David C., Craig, Jamie E., Schadendorf, Dirk, Simms, Lisa A., Burdon, Kathryn P., Nyholt, Dale R., Pooley, Karen A., Orr, Nicholas, Stratigos, Alexander J., Cust, Anne E., Ward, Sarah V., Schulze, Hans-Joachim, Dunning, Alison M., Demenais, Florence, Amos, Christopher I., Kayser, Manfred, Hunter, David J., Newton Bishop, Julia A., Spector, Timothy D., Montgomery, Grant W., Mackey, David A., Smith, George Davey, Nijsten, Tamar E., Bishop, D. Timothy, Bataille, Veronique, Falchi, Mario, Han, Jiali, Martin, Nicholas G.

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-3 (2019)
Nature Communications

The total number of acquired melanocytic nevi on the skin is strongly correlated with melanoma risk. Here we report a meta-analysis of 11 nevus GWAS from Australia, Netherlands, UK, and USA comprising 52,506 individuals. We confirm known loci includi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f47828bc1464fa2cac3bac1339b30ae
https://eprints.whiterose.ac.uk/184029/1/s41467-018-08078-w.pdf