Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Randell G. Young"'
Publikováno v:
Cell Transplantation, Vol 1 (1992)
Cultured-expanded rat marrow-derived mesenchymal cells differentiate into osteoblasts when combined with a porous calcium phosphate delivery vehicle and subsequently implanted in vivo. In this study, the effects of ceramic pretreatment with the cell-
Externí odkaz:
https://doaj.org/article/eafe0890d6b34037ac9df379080393f5
Autor:
Arnold I. Caplan, Alisher Dadabayev, Marc S. Penn, Lori Duesler, Thomas J. Kean, Randell G. Young, David J. Fink, Andrey Olenyik, Joseph Wagner, James E. Dennis
Publikováno v:
J Drug Target
Directing stem cells to the heart is critical in producing an effective cell therapy for myocardial infarction (MI). Mesenchymal stem cells (MSCs) offer an exquisite drug delivery platform with environment-sensing cytokine release and MSCs have shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783b8731172e5d34b2aa0cccfbf4169c
https://doi.org/10.3109/1061186x.2011.622398
https://doi.org/10.3109/1061186x.2011.622398
Autor:
Jeff W.M. Bulte, Randell G. Young, Piotr Walczak, Jian Zhang, Mark F. Pittenger, Dorota A. Kedziorek, Jesús Ruiz-Cabello, Assaf A. Gilad, Peter C.M. van Zijl, Judy Huang
Publikováno v:
Stroke. 39:1569-1574
Background and Purpose— In animal models of stroke, functional improvement has been obtained after stem cell transplantation. Successful therapy depends largely on achieving a robust and targeted cell engraftment, with intraarterial (IA) injection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e4669e0670c49e17c94086f91dece0
https://doi.org/10.1161/strokeaha.107.502047
https://doi.org/10.1161/strokeaha.107.502047
Autor:
Alan W. Heldman, Karl H. Schuleri, Matthew R Gutman, Anastasios Saliaris, Andrew J. Boyle, Randell G. Young, Marco Centola, Luciano C. Amado, Albert C. Lardo, Joshua M. Hare, Behzad N. Oskouei, Jeffrey M. Zimmet, Konstantinos E. Hatzistergos
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 294:H2002-H2011
The underlying mechanism(s) of improved left ventricular function (LV) due to mesenchymal stem cell (MSC) administration after myocardial infarction (MI) remains highly controversial. Myocardial regeneration and neovascularization, which leads to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d7c10143a50ae97ab8924a967b01ce
https://doi.org/10.1152/ajpheart.00762.2007
https://doi.org/10.1152/ajpheart.00762.2007
Autor:
Marian K Rippy, Harold Litt, Seyed M. Hashemi, Susan Ghods, Renu Virmani, Frank D. Kolodgie, Randell G. Young, Kambiz Parcham-Azad, Damir Hamamdzic, Robert L. Wilensky, Martin G. Keane
Publikováno v:
European Heart Journal. 29:251-259
Aims Although mesenchymal stem cells (MSCs) show promising signs in reducing myocardial infarct (MI) size, the safety of endomyocardial delivery and the most efficacious dose is unknown. Methods and results Three days after MI, female Yorkshire swine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a48d7a72bed1725aa6bf2318009c759
https://doi.org/10.1093/eurheartj/ehm559
https://doi.org/10.1093/eurheartj/ehm559
Autor:
Craig A. Thompson, Toby Freyman, Kurt G. Barringhaus, Randell G. Young, Erik Sperry, Kian Keong Poh
Publikováno v:
International Journal of Cardiology. 117:360-364
Background Efficacy of cellular cardiomyoplasty seems to occur in a dose-related manner. However, the safety of multiple transendomyocardial transplantation procedures to administer high cell dosages has not been previously reported. The aims of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff4017ff06a52d88c9179f2ab024cd7
https://doi.org/10.1016/j.ijcard.2006.04.092
https://doi.org/10.1016/j.ijcard.2006.04.092
Autor:
Ronald Hoffman, Robert Dodds, Randell G. Young, Julius V. Turian, Carrington Cobbs, Alastair Morgan Mackay, Prasad Alur, Steven M. Devine, Michael P. Archambault, Jade Borneman, Amelia Bartholomew, Wenxin Pang, Nadim Mahmud, Padmavathy Vanguri
Publikováno v:
Experimental Hematology. 32:494-501
Objective The aim of this study was to examine the effects of the route of administration [intrabone marrow (IBM) vs intravenous (IV)] and the role of conditioning with irradiation in optimizing mesenchymal stem cell (MSC) transplantation. Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4082320b1f3e62e8da12565e6f4e4db5
https://doi.org/10.1016/j.exphem.2004.02.010
https://doi.org/10.1016/j.exphem.2004.02.010
Autor:
Hani A. Awad, Sudha Kadiyala, Randell G. Young, Rania Ibrahim, David L. Butler, Matthew T. Harris, Ying Wu, Gregory P. Boivin
Publikováno v:
Journal of Biomedical Materials Research. 51:233-240
Mesenchymal stem cells (MSCs) were isolated from bone marrow, culture-expanded, and then seeded at 1, 4, and 8 million cells/mL onto collagen gel constructs designed to augment tendon repair in vivo. To investigate the effects of seeding density on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e601040332bd8f7a0af1da5b71961c34
https://doi.org/10.1002/(sici)1097-4636(200008)51:2<233::aid-jbm12>3.0.co
https://doi.org/10.1002/(sici)1097-4636(200008)51:2<233::aid-jbm12>3.0.co
Publikováno v:
Cell Transplantation, Vol 6 (1997)
Mesenchymal Stem Cells (MSCs) possessing the capacity to differentiate into various cell types such as osteoblasts, chondrocytes, myoblasts, and adipocytes have been previously isolated from the marrow and periosteum of human, murine, lapine, and avi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af438332082eb28aeba20f2119cd52e5
https://doi.org/10.1177/096368979700600206
https://doi.org/10.1177/096368979700600206
Autor:
James E. Dennis, Stephen E. Haynesworth, Donald P. Lennon, Arnold I. Caplan, Randell G. Young
Publikováno v:
Experimental Cell Research. 219:211-222
Among the stromal elements in mammalian and avian bone marrow there exists a pluripotent subset of cells which we refer to as mesenchymal stem cells (MSCs). These cells can be isolated and will proliferate in culture. When such subcultured cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8e94f9ae022fcd84ff760960f35a68
https://doi.org/10.1006/excr.1995.1221
https://doi.org/10.1006/excr.1995.1221