Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Randall W. Whitcomb"'
Autor:
Mahmoud N. Ghazzi, Richard S. Legro, Anita Gmerek Fereshetian, Ricardo Azziz, Mary O’Keefe, Randall W. Whitcomb, Rochelle Hanley, David A. Ehrmann
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:1626-1632
We hypothesized that the administration of troglitazone, an insulin-sensitizing agent of the thiazolidinedione class, would improve the ovulatory dysfunction, hirsutism, hyperandrogenemia, and hyperinsulinemia of polycystic ovary syndrome (PCOS) pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6557bd9b27b75db061190647303539a
https://doi.org/10.1210/jcem.86.4.7375
https://doi.org/10.1210/jcem.86.4.7375
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:3169-3176
To assess the effects of troglitazone monotherapy on glycemic control in patients with type 2 diabetes mellitus, we carried out a 6-month, randomized, double-blind, placebo-controlled study in 24 hospital and outpatient clinics in the United States a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed0dfadd9b51cfb9c5d5d46b0fbffeb3
https://doi.org/10.1210/jcem.83.9.5123
https://doi.org/10.1210/jcem.83.9.5123
Autor:
Rebecca Bakker-Arkema, Randall W. Whitcomb, Donald M. Black, Jonathan L. Isaacsohn, Rana Fayyad
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 2:243-249
Background: Atorvastatin calcium (Lipitor) is a new 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The present study was conducted to examine the effect of pronounced cholesterol lowering on adrenal function in patients with sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b464f47e13535876410830d3f772f70
https://doi.org/10.1177/107424849700200402
https://doi.org/10.1177/107424849700200402
Autor:
Alan R. Saltiel, Randall W. Whitcomb
Publikováno v:
Expert Opinion on Investigational Drugs. 4:1299-1309
To date, the treatment of Non-Insulin Dependent Diabetes Mellitus (NIDDM) has focused primarily on attempts to correct some of the metabolic abnormalities commonly associated with the disease. Insulin and/or insulin secretagogues, such as sulphonylur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5658fd2630cb41d638b3394e661eea3
https://doi.org/10.1517/13543784.4.12.1299
https://doi.org/10.1517/13543784.4.12.1299
Autor:
Jose M. Colon, Randall W. Whitcomb, Laura T. Goldsmith, Gerson Weiss, Denise Musket, Nanette Santoro
Publikováno v:
Biology of Reproduction. 50:187-192
To investigate the control of relaxin (Rlx) secretion in men, we studied seminal plasma RIx concentrations after physiologic and supraphysiologic gonadal stimulation. In the first experiment, 14 men with idiopathic hypogonadotropic hypogonadism provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d5a079728692c236ceb998b3e504ce
https://doi.org/10.1095/biolreprod50.1.187
https://doi.org/10.1095/biolreprod50.1.187
Autor:
Patrick M. Sluss, William F. Crowley, Sprengel R, Randall W. Whitcomb, Kathryn A. Martin, Alan L. Schneyer
Publikováno v:
Endocrinology
Although several forms of monomeric alpha-inhibin have been isolated from follicular fluid, no biological function has yet been ascribed to these posttranslationally processed forms of the alpha-subunit precursor protein. Moreover, previous studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4e1eadacfae37dadb7073faff40f93
https://doi.org/10.1210/endo-129-4-1987
https://doi.org/10.1210/endo-129-4-1987
Autor:
David A. Schoenfeld, Joel S. Finkelstein, William F. Crowley, Louis St. L. O’Dea, Christopher Longcope, Randall W. Whitcomb
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 73:609-620
The precise sites of action of the negative feed-back effects of gonadal steroids in men remain unclear. To determine whether testosterone (T) administration can suppress gonadotropin secretion directly at the level of the pituitary, the pituitary re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e5a5861099b189799850b9d99065e4
https://doi.org/10.1210/jcem-73-3-609
https://doi.org/10.1210/jcem-73-3-609
Autor:
Randall W. Whitcomb
Publikováno v:
The Endocrinologist. 1:125-130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1fa13507da55d3293c8eb91e234f17
https://doi.org/10.1097/00019616-199104000-00010
https://doi.org/10.1097/00019616-199104000-00010
Autor:
Ruth Freeman, Randall W. Whitcomb, Janet E. Hall, Patrick M. Sluss, Alan L. Schneyer, William F. Crowley
Publikováno v:
Clinical Chemistry. 37:508-514
We have developed a radioligand receptor assay (RRA) with sufficient sensitivity and specificity for quantifying follitropin (FSH) in unextracted serum samples. Standard curves prepared by adding pituitary FSH to either buffer or gonadotropin-free se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec28020a2116ac6b4a834f278400d73b
https://doi.org/10.1093/clinchem/37.4.508
https://doi.org/10.1093/clinchem/37.4.508
Autor:
Randall W. Whitcomb, Alan L. Schneyer
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 71:591-595
Studies of circulating LH physiology and pathophysiology are dependent upon measurements of immuno- and bioactivity, both of which have methodologic limitations. We have developed and validated a RRA which allows direct measurement of receptor-bindab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e4b3d5aa821db37a99ef3e702e357c
https://doi.org/10.1210/jcem-71-3-591
https://doi.org/10.1210/jcem-71-3-591