Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Randall W. Alfano"'
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Samuel H. Davis, Arlynn F. Mulne, Terry C. Lairmore, Cynthia J. Meininger, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Solid tumor growth is dependent on angiogenesis, the formation of neovasculature from existing vessels. Endothelial activation of the extracellular signal–regulated kinase 1/2, c-jun NH2-terminal kinase, and p38 mitogen-activated protein kinase pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03886c14138c70a9b7f91f12afb7edb8
https://doi.org/10.1158/1541-7786.c.6542080
https://doi.org/10.1158/1541-7786.c.6542080
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Samuel H. Davis, Arlynn F. Mulne, Terry C. Lairmore, Cynthia J. Meininger, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Data from Matrix Metalloproteinase–Activated Anthrax Lethal Toxin Inhibits Endothelial Invasion and Neovasculature Formation during In vitro Morphogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36db606e85f5ec378b3043d47300b02b
https://doi.org/10.1158/1541-7786.22518703.v1
https://doi.org/10.1158/1541-7786.22518703.v1
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Samuel H. Davis, Arlynn F. Mulne, Terry C. Lairmore, Cynthia J. Meininger, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Figures S1-S3 from Matrix Metalloproteinase–Activated Anthrax Lethal Toxin Inhibits Endothelial Invasion and Neovasculature Formation during In vitro Morphogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05495904eb369ab159c26e652d76956f
https://doi.org/10.1158/1541-7786.22518700
https://doi.org/10.1158/1541-7786.22518700
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Jennifer L. Bromberg-White, Keiran S. Smalley, Meenhard Herlyn, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Anthrax lethal toxin (LeTx) shows potent mitogen-activated protein kinase pathway inhibition and apoptosis in melanoma cells that harbor the activating V600E B-RAF mutation. LeTx is composed of two proteins, protective antigen and lethal factor. Upta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf49ee34c5b925ff95f8e167b17aaa7
https://doi.org/10.1158/1535-7163.c.6531849
https://doi.org/10.1158/1535-7163.c.6531849
Autor:
Arthur E. Frankel, Fiemu Nwariaku, Ian C. Mitchell, Nicholas S. Duesbery, Terry C. Lairmore, Janelle M. Ortiz, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Figure 2 from Inhibition of Tumor Angiogenesis by the Matrix Metalloproteinase–Activated Anthrax Lethal Toxin in an Orthotopic Model of Anaplastic Thyroid Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920285fdef28def6f5b8860d66e624c6
https://doi.org/10.1158/1535-7163.22484922.v1
https://doi.org/10.1158/1535-7163.22484922.v1
Autor:
Arthur E. Frankel, Fiemu Nwariaku, Ian C. Mitchell, Nicholas S. Duesbery, Terry C. Lairmore, Janelle M. Ortiz, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Patients with anaplastic thyroid carcinoma (ATC) typically succumb to their disease months after diagnosis despite aggressive therapy. A large percentage of ATCs have been shown to harbor the V600E B-Raf point mutation, leading to the constitutive ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2d30c3526e7719da86d68350687e40
https://doi.org/10.1158/1535-7163.c.6531657.v1
https://doi.org/10.1158/1535-7163.c.6531657.v1
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Jennifer L. Bromberg-White, Keiran S. Smalley, Meenhard Herlyn, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Fig. S2 from Cytotoxicity of the matrix metalloproteinase–activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ca161c3a538d6cee920159db0ec85a
https://doi.org/10.1158/1535-7163.22485246
https://doi.org/10.1158/1535-7163.22485246
Autor:
Arthur E. Frankel, Fiemu Nwariaku, Ian C. Mitchell, Nicholas S. Duesbery, Terry C. Lairmore, Janelle M. Ortiz, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Figure 1 from Inhibition of Tumor Angiogenesis by the Matrix Metalloproteinase–Activated Anthrax Lethal Toxin in an Orthotopic Model of Anaplastic Thyroid Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75094790305f33a2f5a3ebffad0b621d
https://doi.org/10.1158/1535-7163.22484925.v1
https://doi.org/10.1158/1535-7163.22484925.v1
Autor:
Arthur E. Frankel, Nicholas S. Duesbery, Jennifer L. Bromberg-White, Keiran S. Smalley, Meenhard Herlyn, Thomas H. Bugge, Shihui Liu, Stephen H. Leppla, Randall W. Alfano
Supplementary Fig. S1 from Cytotoxicity of the matrix metalloproteinase–activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48dd353b1f6258b380b812e911ada523
https://doi.org/10.1158/1535-7163.22485249.v1
https://doi.org/10.1158/1535-7163.22485249.v1
Autor:
Christopher F. MacManus, Randall W Alfano, Paul Jedlicka, Tom T. Nguyen, Colm B. Collins, Edwin F. de Zoeten
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Inflammatory bowel disease [IBD] is characterised by a disruption of immune homeostasis, which is tightly regulated to protect against harmful pathogens yet not react to commensal antigens. Animal studies indicate that regulatory