Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Randall T. Moon"'
Autor:
Benjamin Cyge, Vera Voronina, Mohammed Hoque, Eunice N. Kim, Jason Hall, Jennifer M. Bailey-Lundberg, Gregory J. Pazour, Howard C. Crawford, Randall T. Moon, Feng-Qian Li, Ken-Ichi Takemaru
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Primary cilia protrude from the apical surface of many cell types and act as a sensory organelle that regulates diverse biological processes ranging from chemo- and mechanosensation to signaling. Ciliary dysfunction is associated with a wide
Externí odkaz:
https://doaj.org/article/887b15da67ff49449b0c627a4c5d0c9c
Autor:
Jason W. Miklas, Shiri Levy, Peter Hofsteen, Diego Ic Mex, Elisa Clark, Jeanot Muster, Aaron M. Robitaille, Gargi Sivaram, Lauren Abell, Jamie M. Goodson, Inez Pranoto, Anup Madan, Michael T. Chin, Rong Tian, Charles E. Murry, Randall T. Moon, Yuliang Wang, Hannele Ruohola-Baker
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103574- (2022)
Summary: Heart disease is the leading cause of death with no method to repair damaged myocardium due to the limited proliferative capacity of adult cardiomyocytes. Curiously, mouse neonates and zebrafish can regenerate their hearts via cardiomyocyte
Externí odkaz:
https://doaj.org/article/642e6fbe603b46798aadc2710661e1bb
Autor:
Peter Hofsteen, Aaron Mark Robitaille, Nicholas Strash, Nathan Palpant, Randall T. Moon, Lil Pabon, Charles E. Murry
Publikováno v:
iScience, Vol 2, Iss , Pp 88-100 (2018)
Summary: Cardiac development requires coordinated biphasic regulation of the WNT/β-catenin signaling pathway. By intersecting gene expression and loss-of-function siRNA screens we identified Alpha Protein Kinase 2 (ALPK2) as a candidate negative reg
Externí odkaz:
https://doaj.org/article/7af71fc9827042cf9fe6669709f29e0f
Autor:
Inchul Lee, Kyuyoung Song, Randall T. Moon, Hyunlyoung Koo, Juhee Park, Jungtae Kim, Youngmi Kim, Eunsoon Kim, Kyungho Choi, Seunghyun Bang, Yusun Jung
Supplementary Figure S2 from TC1 (C8orf4) Enhances the Wnt/β-Catenin Pathway by Relieving Antagonistic Activity of Chibby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebcde6684f84c1c8bae2a4eee6d5683
https://doi.org/10.1158/0008-5472.22366554.v1
https://doi.org/10.1158/0008-5472.22366554.v1
Autor:
Inchul Lee, Kyuyoung Song, Randall T. Moon, Hyunlyoung Koo, Juhee Park, Jungtae Kim, Youngmi Kim, Eunsoon Kim, Kyungho Choi, Seunghyun Bang, Yusun Jung
The Wnt/β-catenin pathway has been implicated in human cancers. Here, we show that TC1 (C8orf4), a small protein present in vertebrates, functions as a positive regulator of the pathway. TC1 interacts with Chibby (Cby) and thereby enhances the signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c37b356334ac7c85ed0b1960bdac859
https://doi.org/10.1158/0008-5472.c.6495195
https://doi.org/10.1158/0008-5472.c.6495195
Autor:
Feng-Qian Li, Mohammed Hoque, Benjamin Cyge, Howard C. Crawford, Eunice N Kim, Randall T. Moon, Ken-Ichi Takemaru, Gregory J. Pazour, Jennifer M. Bailey-Lundberg, Jason C. Hall, Vera Voronina
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Primary cilia protrude from the apical surface of many cell types and act as a sensory organelle that regulates diverse biological processes ranging from chemo- and mechanosensation to signaling. Ciliary dysfunction is associated with a wide array of
Publikováno v:
Stem Cell Reports, Vol 5, Iss 2, Pp 291-304 (2015)
The in vitro derivation of hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) is complicated by the existence of multiple overlapping embryonic blood cell programs called primitive, erythromyeloid progenitor (EMP), and definitive. As
Externí odkaz:
https://doaj.org/article/da508e4d3c664f6a95b26428137b103d
Autor:
Nicholas C. Robin, Zsuzsa Agoston, Travis L. Biechele, Richard G. James, Jason D. Berndt, Randall T. Moon
Publikováno v:
Stem Cell Reports, Vol 2, Iss 1, Pp 9-17 (2014)
Statins improve recovery from traumatic brain injury and show promise in preventing Alzheimer disease. However, the mechanisms by which statins may be therapeutic for neurological conditions are not fully understood. In this study, we present the ini
Externí odkaz:
https://doaj.org/article/d20a855c8bf24cb5bde1c04817b11d3a
Autor:
Jason W. Miklas, Shiri Levy, Peter Hofsteen, Diego Ic Mex, Elisa Clark, Jeanot Muster, Aaron M. Robitaille, Gargi Sivaram, Lauren Abell, Jamie M. Goodson, Inez Pranoto, Anup Madan, Michael T. Chin, Rong Tian, Charles E. Murry, Randall T. Moon, Yuliang Wang, Hannele Ruohola-Baker
Publikováno v:
iScience
iScience, Vol 25, Iss 1, Pp 103574-(2022)
iScience, Vol 25, Iss 1, Pp 103574-(2022)
Summary Heart disease is the leading cause of death with no method to repair damaged myocardium due to the limited proliferative capacity of adult cardiomyocytes. Curiously, mouse neonates and zebrafish can regenerate their hearts via cardiomyocyte d
Publikováno v:
Cancers, Vol 2, Iss 2, Pp 1000-1012 (2010)
Given the pivotal roles of morphogen pathways including Wnt, Notch, Hedgehog, and BMP pathways in the development of the neural crest lineage, it is not surprising that these signaling networks have also been implicated in the biology of malignant me
Externí odkaz:
https://doaj.org/article/b7b28ee8dcf34b17a3f9fe9b51d92768