Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Randall T, Peterson"'
Autor:
Junyan Ma, Weiting Zhang, Simin Rahimialiabadi, Nikkitha Umesh Ganesh, Zhengwang Sun, Saba Parvez, Randall T. Peterson, Jing-Ruey Joanna Yeh
Publikováno v:
Biology Open, Vol 13, Iss 9 (2024)
Externí odkaz:
https://doaj.org/article/406817cbd67f49b0a8db399159b68807
Akademický článek
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Autor:
Tejia Zhang, Ivy Alonzo, Chris Stubben, Yijie Geng, Chelsea Herdman, Nancy Chandler, Kim P. Doane, Brock R. Pluimer, Sunia A. Trauger, Randall T. Peterson
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/065ca1ea11a045ab97d6f22af2ea1fea
Autor:
Brock R. Pluimer, Devin L. Harrison, Chanon Boonyavairoje, Eric P. Prinssen, Mark Rogers-Evans, Randall T. Peterson, Summer B. Thyme, Anjali K. Nath
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107099- (2023)
Summary: DISC1 is a genetic risk factor for multiple psychiatric disorders. Compared to the dozens of murine Disc1 models, there is a paucity of zebrafish disc1 models—an organism amenable to high-throughput experimentation. We conducted the longit
Externí odkaz:
https://doaj.org/article/b4147e26af0a467eae8c8a1f5c5fdeeb
Autor:
Jason R. Nielson, Anjali K. Nath, Kim P. Doane, Xu Shi, Jangwoen Lee, Emily G. Tippetts, Kusumika Saha, Jordan Morningstar, Kevin G. Hicks, Adriano Chan, Yanbin Zhao, Amy Kelly, Tara B. Hendry-Hofer, Alyssa Witeof, Patrick Y. Sips, Sari Mahon, Vikhyat S. Bebarta, Vincent Jo Davisson, Gerry R. Boss, Jared Rutter, Calum A. MacRae, Matthew Brenner, Robert E. Gerszten, Randall T. Peterson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Although cyanide’s biological effects are pleiotropic, its most obvious effects are as a metabolic poison. Cyanide potently inhibits cytochrome c oxidase and potentially other metabolic enzymes, thereby unleashing a cascade of metabolic pe
Externí odkaz:
https://doaj.org/article/cb54f482aaef485c9442a4f1d31f3076
Publikováno v:
PLoS Genetics, Vol 18, Iss 6 (2022)
NGLY1 deficiency, a rare disease with no effective treatment, is caused by autosomal recessive, loss-of-function mutations in the N-glycanase 1 (NGLY1) gene and is characterized by global developmental delay, hypotonia, alacrima, and seizures. We use
Externí odkaz:
https://doaj.org/article/a3ea1336b01f4a54b35171cbefbf3fc4
Efficacy of Ciprofloxacin/Celecoxib combination in zebrafish models of amyotrophic lateral sclerosis
Autor:
Hagit Goldshtein, Alexandre Muhire, Virginie Petel Légaré, Avital Pushett, Ron Rotkopf, Jeremy M. Shefner, Randall T Peterson, Gary A. B. Armstrong, Niva Russek‐ Blum
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 10, Pp 1883-1897 (2020)
Abstract Objective To evaluate the efficacy of a fixed‐dose combination of two approved drugs, Ciprofloxacin and Celecoxib, as a potential therapeutic treatment for amyotrophic lateral sclerosis (ALS). Methods Toxicity and efficacy of Ciprofloxacin
Externí odkaz:
https://doaj.org/article/b113a40b6b6d4087b0de396e6c9a5c30
Autor:
Matthew N. McCarroll, Leo Gendelev, Reid Kinser, Jack Taylor, Giancarlo Bruni, Douglas Myers-Turnbull, Cole Helsell, Amanda Carbajal, Capria Rinaldi, Hye Jin Kang, Jung Ho Gong, Jason K. Sello, Susumu Tomita, Randall T. Peterson, Michael J. Keiser, David Kokel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Some anesthetics despite being generally associated with sedation, can also increase brain activity—a phenomenon called paradoxical excitation. The authors identified dozens of compounds that generally decrease neuronal activity, but increase activ
Externí odkaz:
https://doaj.org/article/800557a8a9ec49a7a80e98ddf53a8be2
Autor:
Calum A, MacRae, Randall T, Peterson
Publikováno v:
Annual Review of Pharmacology and Toxicology. 63:43-64
Pharmacology and toxicology are part of a much broader effort to understand the relationship between chemistry and biology. While biomedicine has necessarily focused on specific cases, typically of direct human relevance, there are real advantages in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caccecbf696df4ab001e4d66b27e2231
https://doi.org/10.1146/annurev-pharmtox-051421-105617
https://doi.org/10.1146/annurev-pharmtox-051421-105617
Autor:
Vik S Bebarta, Xu Shi, Shunning Zheng, Tara B Hendry-Hofer, Carter C Severance, Matthew M Behymer, Gerry R Boss, Sari Mahon, Matthew Brenner, Gregory T Knipp, Vincent Jo Davisson, Randall T Peterson, Calum A MacRae, Jared Rutter, Robert E Gerszten, Anjali K Nath
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology, vol 191, iss 1
Cyanide—a fast-acting poison—is easy to obtain given its widespread use in manufacturing industries. It is a high-threat chemical agent that poses a risk of occupational exposure in addition to being a terrorist agent. FDA-approved cyanide antido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a5665cbc5902db4af2577274e5b564
https://doi.org/10.1093/toxsci/kfac116
https://doi.org/10.1093/toxsci/kfac116