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Autor:
T. Rosario-Jansen, Roy L. M. Dobson, L. I. Wu, Michael Wiard Scherz, D. E. Kellstein, Kenneth R. Wehmeyer, J. M. Ridgeway, Randall Stryker Matthews, Lixian Gan, I. J. Magrisso, Debra L. Kuhlenbeck, D. Hennes, P. A. Young, K. Enzweiler, J. L. Tulich, R. Darolia, S. A. Green, Thomas H. Eichhold, John Michael Janusz, S. P. Sirko, R. W. Farmer
Publikováno v:
Journal of Medicinal Chemistry. 41:1112-1123
A series of 5-keto-substituted 7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofurans (DHDMBFs) were prepared and evaluated as potential nonsteroidal antiinflammatory and analgesic agents. Interest in this class of compounds arose when a DHDMBF was found t