Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Randall Moreadith"'
Publikováno v:
Movement Disorders. 35:1055-1061
Background Extensive scientific and clinical evidence indicates that continuous delivery of a dopaminergic agent is associated with significant reduction in motor complications compared with intermittent oral dosing with the same agent. There has bee
Autor:
Randall Moreadith, Leslie E. Grayson, E. Martina Bebin, Steve B. Ampah, Tyler E. Gaston, Kathleen A. Hernando, Jerzy P. Szaflarski
Publikováno v:
Epilepsy & Behavior. 95:131-136
The objective of this study was to determine the relationship between cannabidiol (CBD) dose, CBD plasma level, and seizure control in a large open-label single-center study.All participants with treatment-refractory epilepsy participating in our exp
Autor:
Xiuling Li, Michael D. Bentley, Christoph Rader, Rebecca Weimer, Warren Olanow, Bekir Dizman, Tacey X. Viegas, Kunsang Yoon, J. Milton Harris, Zhihao Fang, Brendan P. Rae, Randall Moreadith, David G. Standaert
Publikováno v:
European Polymer Journal. 88:524-552
The potential of poly (2-oxazoline) or POZ to be a versatile and broad based platform for drug delivery with wide utility in multiple therapeutic areas has long been recognized by experts in the field. This feature article provides a case study which
Autor:
Tacey X. Viegas, Randall Moreadith
Publikováno v:
Polymers for Biomedicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8df4558a56b3cff39c6e6cc9530cdec3
https://doi.org/10.1002/9781118967904.ch3
https://doi.org/10.1002/9781118967904.ch3
Autor:
Tom H. Johnston, Bekir Dizman, David G. Standaert, Michael D. Bentley, Zhihao Fang, Michael Hill, Randall Moreadith, Kunsang Yoon, Rebecca Weimer, Karen L. Eskow Jaunarajs, Jonathan M. Brotchie, Paula Ravenscroft, Tacey X. Viegas
Publikováno v:
Movement Disorders. 28:1675-1682
Currently available dopaminergic drugs such as levodopa and dopamine (DA) receptor agonists impart considerable improvement in Parkinson's disease (PD) motor symptoms but often lead to signifi- cant motor complications including "wearing-off" and dys
Autor:
Cindy L. Grines, Randall Moreadith, Timothy D. Henry, Matthew W. Watkins, Nabil Dib, Gérald Barbeau, Tony Andrasfay, Robert L. Engler
Publikováno v:
Journal of the American College of Cardiology. 50:1038-1046
Objectives The goal of this study was to explore the effects of angiogenic gene therapy. Background Preclinical studies with intracoronary administration of Ad5FGF-4 (alferminogene tadenovec, Generx, Berlex Biosciences, Richmond, California) suggeste
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 28:953-963
Staphylokinase, a bacterially-derived protein which functions as a plasminogen activator, has potential utility as a human therapeutic for thrombotic disorders. A recombinant version of this protein, SY161, contains 13 amino acid substitutions design
Autor:
Timothy D, Henry, Cindy L, Grines, Matthew W, Watkins, Nabil, Dib, Gerald, Barbeau, Randall, Moreadith, Tony, Andrasfay, Robert L, Engler
Publikováno v:
Journal of the American College of Cardiology. 50(11)
The goal of this study was to explore the effects of angiogenic gene therapy.Preclinical studies with intracoronary administration of Ad5FGF-4 (alferminogene tadenovec, Generx, Berlex Biosciences, Richmond, California) suggested it could induce angio
Autor:
Siddharth J. Advant, Frank K. Bedu-Addo, Randall Moreadith, Greg Conn, Min Wan, Mabel Royal, Catharine Johnson
Publikováno v:
Biomedical chromatography : BMC. 17(5)
Staphylokinase variant SY161 is a recombinant mutant of the Staphylococcus aureus polypeptide staphylokinase (Sak), and is currently in human clinical trials as a thrombolytic agent. The 15 kDa single chain SY161 protein is expressed as a soluble cyt
Autor:
Sophie Danloy, Veerle Kreemers, Desire Collen, Luc Schoonjans, Yves Laroche, Randall Moreadith
Publikováno v:
Stem cells (Dayton, Ohio). 21(1)
Genetically altered mice may exhibit highly variable phenotypes due to the variation in genetic background, which can only be circumvented by generation of inbred, isogenic gene-targeted and control mice. Here we report that an embryonic stem (ES) ce